Tricosanoic acid is an endogenous agonist of long-chain saturated fatty acids and free fatty acid receptor FFAR1, which can activate hair growth. It can improve cognitive function by regulating neuronal membrane fluidity, inhibiting neuroinflammatory response, participating in myelination, and neuronal energy metabolism. Levels are low in Alzheimer's disease (AD) models, while higher serum concentrations correlate with better cognitive performance. It can also be used as a biomarker for diseases related to cognitive decline.
- Target: Free Fatty Acid Receptor
- Research areas: Neurological disease, metabolic disease
- Structural classification: Ketones, aldehydes, acids
- Application fields: Metabolic disease, endogenous metabolite