Lipids and Lipid Derivatives
Medchemexpress LLC Guaiacol-d3 | 74495-69-5 | 127.16 | 50 MG
Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cortodoxone-d2 | 1271728-08-5 | 99.0% | C21H28D2O4 | 1 MG
Cortodoxone-d2 is a deuterium labeled glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). It is suitable for use as a tracer or an internal standard for quantitative analysis in various analytical techniques.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation in drug development.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC HY-10001 5mg Medchemexpress, Calcipotriol CAS:112965-21-6 Purity:>98%
Medchemexpress, HY-10001 5mg Calcipotriol CAS:112965-21-6 Calcipotriol is a synthetic VitD 3 analogue with a high affinity for the vitamin D receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 | C15H22ClN3O | 5 MG
Dopamine D2 receptor agonist-3 is a small-molecule research compound that acts as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist, with reported in vitro potency and demonstrated brain penetration in vivo. It is supplied as a solid (white to off-white) with high stated purity for laboratory use.
- Selective D2 partial agonist and D3 antagonist activity.
- Potency reported as pEC50 D2 = 8.3; D3 < 5.5 (approx. D2 EC50 ≈ 5 nM).
- Demonstrated brain penetration (brain:blood ratio 5.5; Tmax 0.5 h at 3 mg/kg, s.c.).
- High purity (98.3%) suitable for research applications.
- Solid, white to off-white appearance, available in small research pack sizes.
Medchemexpress LLC HY-15398 1g Medchemexpress, Vitamin D3 CAS:67-97-0 Purity:>98%
Medchemexpress, HY-15398 1g Vitamin D3 CAS:67-97-0 Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502479365.JPG-250.jpg)
eMolecules 54668-67-6 | CHOL-5-ENE-3-BETA,24-DIOL | AstaTech360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657
CHOL-5-ENE-3-BETA,24-DIOL | AstaTech | 54668-67-6360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657
Medchemexpress LLC Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-d3, sodium salt (1:1) | 1219805-09-0 | 99.2% | C₁₃H₁₄D₃NaO₂ | 1 MG
This Ibuprofen-d3 sodium product is a white to off-white solid. It exhibits high purity and isotopic enrichment, complying with specified analytical standards.
- Appearance: White to off-white solid
- Purity (HPLC): 99.21%
- Isotopic enrichment: 99.9%
- Recommended storage: 4°C, sealed, away from moisture
- Recommended storage in solvent: -80°C for up to 6 months; -20°C for up to 1 month, sealed and away from moisture
Medchemexpress LLC Nudifloramide-d3 | 1207384-48-2 | 99.4% | 155.17 | 1 MG
Nudifloramide-d3 (2PY-d3) is a deuterium labeled Nudifloramide. It is an end product of nicotinamide-adenine dinucleotide (NAD) degradation and significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro. Deuteration, the incorporation of stable heavy isotopes, allows it to be used as a tracer during drug development, affecting pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
eMolecules 57333-96-7 | Medchem Express | Tacalcitol | 1mg | 446270814 | HY-32337 | MFCD00866623 | 416.646 | C27H44O3
Medchem Express | Tacalcitol | 1mg | 446270814 | HY-32337 | 57333-96-7 | MFCD00866623 | 416.646 | C27H44O3
Medchemexpress LLC HY-10002 2mg Medchemexpress, Calcitriol CAS:32222-06-3 Purity:>98%
Medchemexpress, HY-10002 2mg Calcitriol CAS:32222-06-3 Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Melatonin-d3 (N-acetyl-5-methoxytryptamine-d3) | 90735-69-6 | 99.2% | C13H13D3N2O2 | 1 MG
Melatonin-d3 is a deuterium-labeled form of Melatonin, a hormone produced by the pineal gland. Melatonin activates melatonin receptors and is known for its role in sleep, as well as its significant antioxidative and anti-inflammatory properties. It has been identified as a novel selective ATF-6 inhibitor and can induce apoptosis in human hepatoma cells by downregulating COX-2. Additionally, Melatonin has been shown to attenuate palmitic acid-induced mouse granulosa cell apoptosis through endoplasmic reticulum stress.
- Deuterium labeled
- Tracer
- Internal standard for quantitative analysis
- Pharmacokinetic studies
Sigma Aldrich Fine Chemicals Biosciences 24R2425 Dihydroxyvitamin D
(24R)-24 25-Dihydroxyvitamin D3 is a metabolite of vitamin D3. It is known to increase bone volume and mechanical strength.(24R) 24 25-Dihydroxyvitamin D3-26 26 26 27 27 27-d6nbspis a deuterated metabolite of vitamin D3 wherein methyl protons of C-26 C-27 carbons are replaced by deuterium.
Medchemexpress LLC D3/5-HT receptor modulator-1 | 898532-85-9 | 391.51 | 1 ML
D3/5-HT receptor modulator-1 (compound 5i) is a selective dopamine D3 receptor and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist. It has a low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels, and presents an atypical antipsychotic profile.
- Selective dopamine D3 receptor and 5-HT2A receptor antagonist.
- Partial 5-HT1A receptor agonist.
- Shows Ki values of 4.5 nM (D3), 11.9 nM (5-HT2A), and 15.3 nM (5-HT2A).
- Low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels.
- Atypical antipsychotic profile.
Medchemexpress LLC Verapamil-d3 hydrochloride | 2714485-49-9 | 99.57% | C27H36D3ClN2O4 | 5 MG
Verapamil-d3 hydrochloride is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride is a calcium channel blocker and a potent, orally active first-generation P-glycoprotein (P-gp) inhibitor. It also inhibits CYP3A4 and has potential for research into high blood pressure, heart arrhythmias, and angina.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC (R)-Vitamin D2 | 116559-84-3 | >98.6% | C28H44O | 50 MG
(R)-Vitamin D2 is an isomer of Vitamin D2 (HY-76542) and can be utilized as an experimental control. Vitamin D2 (Ergocalciferol), derived from plant sources or dietary supplements, can be employed as a Vitamin D supplement. This product is exclusively for research purposes and is not intended for patient use.
- Isomer of vitamin D2
- Can be used as an experimental control
- Derived from plant sources or dietary supplements
- Can be employed as a vitamin D supplement
- Exclusively for research purposes