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RKH acetate exerts protective effects against sepsis-induced death and organ damage. It directly binds to Toll-like receptor 4 (TLR4) and blocks TLR4 signal transduction in immune cells. It is for research use only.
Target: TLR4
Appearance: Solid
Color: White to off-white
Sequence: Arg-Lys-His
Solubility in DMSO: 200 mg/mL
Solubility in H2O: ≥ 30 mg/mL
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Vitamin D receptor (VDR) acts as a nuclear receptor for calcitriol the active form of vitamin D3 triggering cellular effects After vitamin D3 binding VDR translocates to the nucleus and forms a heterodimer with the retinoid X receptor (RXR) Vitamin D Receptor/VDR Protein Human (sf9 His) is the recombinant human-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-10 His labeled tag
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Glatiramer acetate (GA) is a synthetic immunomodulatory polypeptide structurally composed of random sequences of four amino acids GA modulates immune responses mainly through affecting dendritic cell (DC) function In vitro studies indicate GA suppresses IL-12p70 secretion in immature DC following lipopolysaccharide stimulation promoting DC differentiation favoring Th2 lineage cells and elevated IL-10 production Further in vivo studies reveal GA treatment alters cytokine profiles and enhances expression of neurotrophic factors such as BDNF NT-3 and NT-4 within specific brain regions of experimental autoimmune encephalomyelitis mouse models highlighting its utility in immune research and autoimmune disease investigations
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sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. It stimulates growth hormone secretion and can also be used as an inducer of ovulation by artificial insemination. This product is intended for research use only.
Increases GH mRNA levels
Stimulates GH secretion in a dose-dependent manner
Induces growth hormone levels in common carp pituitary fragments
Serves as an inducer of ovulation by artificial insemination
Intended for research use only
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GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that blocks the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). This compound enhances free thrombin generation and has demonstrated significant therapeutic potential in animal models, alleviating DSS-induced colitis by improving body weight loss and mortality.