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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Flavin adenine dinucleotide (Standard) is the analytical standard of Flavin adenine dinucleotide. Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. This product is intended for research and analytical applications.
Used as a reference standard assay
Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Involved in important enzymatic reactions in metabolism
Functions as a redox cofactor
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Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor and a prosthetic group of a protein. It is involved in several important enzymatic reactions in metabolism.
Endogenous metabolite
Redox cofactor
Prosthetic group of a protein
Involved in several enzymatic reactions in metabolism
Appearance: solid
Color: yellow to orange
Molecular weight: 829.51
Formula: C27H31N9Na2O15P2
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3AE-phosphoadenosine 5AE-phosphate (PAP) a 3AE-phosphorylated nucleotide is found in almost all organisms and is obtained as a by-product of sulfur and lipid metabolism.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor. purity: 98%
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Glutathione oxidized is produced by the oxidation of glutathione. It is involved in the detoxification of reactive oxygen species and can be used for research on sickle cells and erythrocytes.
Involved in the detoxification of reactive oxygen species.
Applicable for research involving sickle cells and erythrocytes.
Formulated as 10 mM in 1 mL of water.
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7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog is a potent cap-dependent translation inhibitor.
Potent cap-dependent translation inhibitor.
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Exists as a 557AkDa hexadecamer composed of eight heavy chains each with a molecular weight of approximately 56AkDa and eight light chains of molecular weight 14AkDa. Each molecule contains one magnesium ion. pH optimum ~7.9. KM for CO2 ~0.45 mM. Ribulose diphosphate becomes inhibitory at concentrations exceeding 0.7 mM. Orthophosphate and ammonium sulfate are competitive inhibitors. 3-Phosphoglycerate is a noncompetitive inhibitor.
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Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
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Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 3'-Deoxyguanosine is a ligand that can be complexed with enzymes such as purine nucleoside phosphorylase and receptors. purity: 98%
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Flavin-Containing Monooxygenase-3 (FMO3) is a member of the flavin-containing monooxygenase (FMO) family of enzymes. It is highly expressed in the human liver.
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7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
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