Nucleosides and Analogues
Medchemexpress LLC Recombinant human adenosine kinase | >95.0% | 50 UG
Recombinant human adenosine kinase (ADK) is a full-length, tag-free enzyme produced in HEK293 cells for biochemical and enzymatic research. Supplied as a filtered solution with stabilizers, it offers consistent activity and low endotoxin for reliable assay results.
- Full-length human sequence (M1-H345).
- Expressed in HEK293 mammalian cells for native folding.
- Tag free to minimize assay interference.
- Purity >95% as determined by reducing SDS-PAGE.
- Formulated in 20 mM Tris, 300 mM NaCl, pH 8.0, with stabilizers and 20% glycerol.
- Endotoxin <1 EU/μg and measured specific activity for activity-based assays.
- Supplied as a frozen solution and shipped on dry ice to preserve activity.
Abcam Iodotubercidin, adenosine kinase inhibitor, 1MG
MW 392.15 Da, Purity >95%. Potent, specific adenosine kinase inhibitor (IC₅₀ = 26 nM). Inhibits platelet aggregation and spreading, and interferes with adenosine and adenine nucleotide metabolism. Additionally inhibits other kinases such as ERK2 (Ki = 525 nM).
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Rhodizonic acid diso 5g
Rhodizonic acid disodium (Sodium rhodizonate dibasic) can be used as an indicator in the volumetric determination of barium and sulfates Rhodizonic acid disodium is a kind of biological materials or organic compounds that are widely used in life science research[1]
Medchemexpress LLC Uridine | 58-96-8 | 100.0% | 5 G
Uridine is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. This compound is used for research purposes and has demonstrated various biological activities.
- Inhibits the proliferation of HL-60 leukemia cells
- Alleviates CCl4-induced liver fibrosis in mice
- Shows anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models
Medchemexpress LLC 2'-Deoxyguanosine 5'-monophosphate disodium hydrate | 146877-98-7 | 99.0% | C10H14N5O7.H2O.2Na | 50 MG
2'-Deoxyguanosine 5'-monophosphate (dGMP) disodium hydrate is an oxidizable target of pterin (PT) used to evaluate the photosensitizing properties of biopterins. Pterin induces a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage via two primary mechanisms: electron transfer (type I) and singlet molecular oxygen production (type II).
- Oxidizable target of pterin (PT).
- Evaluates photosensitizing properties of biopterins.
- Induces DNA damage under UV-A radiation.
- Functions through Type I (electron transfer) and Type II (singlet molecular oxygen production) mechanisms.
- Relevant to cell cycle and DNA damage studies.
- Involved in DNA/RNA synthesis research.
Medchemexpress LLC 7-Methyl-guanosine-5'-triphosphate sodium | 5 MG
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog is a potent cap-dependent translation inhibitor.
- Potent cap-dependent translation inhibitor.
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5'-triphosphate sodium salt hydrate >=95% (HPLC), powder | 36051-31-7 | MFCD00077781 | 1G
Guanosine 5'-triphosphate sodium salt hydrate >=95% (HPLC), powder | Purity: >=95% (HPLC) | 36051-31-7 | MFCD00077781 | 1G
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5′-triphosphate sodium salt hydrate | 36051-31-7 | MFCD00077781 | 25mg
Guanosine 5′-triphosphate sodium salt hydrate | 36051-31-7 | MFCD00077781 | 25mg
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5′-triphosphate sodium salt hydrate powder | 36051-31-7 | MFCD00077781 | 100mg
Guanosine 5′-triphosphate sodium salt hydrate powder | Purity: 95% | Mol Wt: 523.18 | 36051-31-7 | MFCD00077781 | 100mg
Medchemexpress LLC D-(+)-glucosamine hydrochloride | 66-84-2 | 215.63 | 50 MG
Glucosamine hydrochloride is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, also used as a dietary supplement. It is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, exerting pharmacological effects on osteoarthritic cartilage and chondrocytes. This product exhibits dose-dependent DPPH antioxidant activity and inhibits HIF-1α at the protein level.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 251.24 g/mol | C10H13N5O3 | 50 MG
2'-Deoxyadenosine is an adenine nucleoside used as a research reagent and analytical standard. It inhibits glucose-stimulated insulin release, modulates islet cAMP, activates caspase-3, and has been reported to inhibit S-adenosyl-L-homocysteine hydrolase; it is used in analytical and biochemical studies.
- intended for research and analytical applications
- inhibits glucose-stimulated insulin release
- modulates islet cyclic AMP and activates caspase-3
- reported inhibitor of S-adenosyl-L-homocysteine hydrolase
- available in labeled and standard variants for analytical use
Apexbio Technology LLC Lamivudine 134678-17-4 50mg
Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses