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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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A thymidine nucleoside derivative commonly used to identify proliferating cells; intraperitoneal injection of BrdU can be used in combination with neuronal markers to detect adult neurogenesis in animal models; commonly used as a marker of proliferation of cancer cells in vitro
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2'-Deoxycytidine-5'-monophosphate (also known as 2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. It is a deoxynucleotide building block that constitutes DNA. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thus supporting DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block of DNA
Can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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A derivative of uridine; hepatitis C polyU/UC RNA strands containing 2'-FdU bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells; has been used as a starting material in the synthesis of RSV polymerases inhibitors
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Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) . purity: 99%
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A nucleoside derivative; inhibits the proliferation of BHK-21 cells and Ehrlich ascites tumor cells (IC50s = 4 and 6 µM, respectively); reduces virus yield in psuedorabies-infected BHK-21 cells at 1 mM; a product of oxidative DNA damage in vitro
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