Nucleosides and Analogues
Medchemexpress LLC Adenosine, 8-bromo-2'-deoxy- | 14985-44-5 | ≥98.0% | 330.14 | 10 MM 1 ML
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 25 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This product is for research use only and not for sale to patients.
- Treatment results in rapid cell death for the vast majority of cancer cell lines tested, with IC50s between 0.7-2.9 μM.
- In A549 lung cancer cell-based mouse xenograft studies, it causes a decrease of the tumor growth rate, superior to that observed with 6-thioguanine treatment.
- It increases telomere dysfunction in tumor cells in vivo.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 99.9% | 267.25 | 10 G
2'-Deoxyguanosine is a purine nucleoside with diverse biological activities, known to induce DNA division in mouse thymus cells and act as a potent cell division inhibitor in plant cells. It also demonstrates inhibitory effects on the clonal growth of HL-60 and K562 leukemia cells, with observed IC50 values of 50 and 80 μM, respectively. This compound typically appears as a solid, ranging from white to off-white in color.
- Endogenous metabolite
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC 2'-Deoxyguanosine-d13 | 961-07-9 | 99.9% | 280.32 | 5 MG
2'-Deoxyguanosine-d13 is a deuterium-labeled version of 2'-Deoxyguanosine. It is intended for research use only and can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC N6-Threonylcarbamoyladenosine | 24719-82-2 | 99.6% | 412.35 | 1 MG
N6-Threonylcarbamoyladenosine is a common nucleoside that can decorate and become tRNA. It is for research use only.
- Purity of 99.62%
- Molecular weight of 412.35
- Chemical formula: C15H20N6O8
- Appearance: Solid
- Color: Off-white to light brown
- Storage conditions: -20°C for powder, -80°C for 6 months in solvent
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 25mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Sigma Aldrich Fine Chemicals Biosciences Beta-Nicotinamide Adenine Dinucleotide Hydrate | 53-84-9 | MFCD00036253 | 1g
Beta-Nicotinamide Adenine Dinucleotide Hydrate | Purity: 99% | Mol Wt: 663.43 (anhydrous basis) | 53-84-9 | MFCD00036253 | 1g
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5 monophosphate25G
REAGENT Adenosine 5 monophosphate25G
Sigma Aldrich Fine Chemicals Biosciences β-Nicotinamide adenine dinucleotide hydrate | 53-84-9 | MFCD00036253 | 5g
β-Nicotinamide adenine dinucleotide hydrate | Purity: ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), | MW:663.43 (anhydrous basis) | 53-84-9 | MFCD00036253 | 5g
Sigma Aldrich Fine Chemicals Biosciences 5-Bromo-2′-deoxyuridine | 59-14-3 | MFCD00006529 | 500mg
5-Bromo-2′-deoxyuridine | Purity: ≥99% (HPLC) | MW:307.1 | 59-14-3 | MFCD00006529 | 500mg
Sigma Aldrich Fine Chemicals Biosciences Adenosine-13C1015N5 5-mono1MG
REAGENT Adenosine-13C1015N5 5-mono1MG
Sigma Aldrich Fine Chemicals Biosciences 3'-Azido-3'-deoxythymidine >=98% (HPLC) | 30516-87-1 | MFCD00006536 | 250MG
3'-Azido-3'-deoxythymidine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 267.24 | 30516-87-1 | MFCD00006536 | 250MG
Sigma Aldrich Fine Chemicals Biosciences beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | 53-84-9 | MFCD00036253 | 25G
beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | Purity: >=96.5% (HPLC); >=96.5% (spectrophotometric assay) | 53-84-9 | MFCD00036253 | 25G
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine100MG
beta Nicotinamide adenine100MG
Sigma Aldrich Fine Chemicals Biosciences 5-Fluoro-2′-deoxyuridine | 50-91-9 | MFCD00006530 | 100mg
5-Fluoro-2′-deoxyuridine | MW:246.19 | 50-91-9 | MFCD00006530 | 100mg