Organometallic Compounds
Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 25 MG
DNP-PEG3-azide is a PEG-based PROTAC linker crucial for the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an azide group that enables both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. It is a light yellow to yellow viscous liquid with a high purity of 99.18%.
Medchemexpress LLC m-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 25 G
m-PEG5-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by utilizing the intracellular ubiquitin-proteasome system. They achieve this by connecting two ligands: one for an E3 ubiquitin ligase and another for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG
Azido-PEG3-C3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC M-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 1 G
m-PEG3-Aminooxy is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. This product is intended strictly for research purposes and is not for patient use.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- For research use only
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 50 G
Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 10 G
m-PEG5-Br is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting the protein of interest. These compounds function by exploiting the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 100 MG
This compound serves as a PEG-based linker for assembling Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed with two distinct ligands connected by such a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This design enables PROTACs to leverage the cell's ubiquitin-proteasome system for the targeted degradation of proteins.
- Functions as a linker for PROTACs.
- Utilizes the ubiquitin-proteasome system.
- Enables targeted protein degradation.
Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | MFCD00010996 | 99.0% | C11H25NO5 | 1 G
m-PEG5-NH2 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs function by connecting two ligands-one for an E3 ubiquitin ligase and another for a target protein-to leverage the intracellular ubiquitin-proteasome system for selective protein degradation. The product has a purity of 99.02%.
- Peg-based protac linker
- Used in the synthesis of protacs
- Facilitates protein degradation via the ubiquitin-proteasome system
- High purity
Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 1 G
Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker designed for the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Suitable for PROTAC synthesis
- Molecular weight: 308.37
- Targeted for PROTAC linkers pathway
- Recommended storage: 4°C, sealed, away from moisture and light (solid); -80°C for 6 months or -20°C for 1 month (in solvent)
eMolecules Ambeed / 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate / 250mg / 525081440 / A165302 / / 77544-68-4 / MFCD18433414 / 304.360 / C13H20O6S
Ambeed / 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate / 250mg / 525081440 / A165302 / / 77544-68-4 / MFCD18433414 / 304.360 / C13H20O6S
Medchemexpress LLC Azido-PEG3-SSPy | 98.6% | 344.45 g·mol⁻¹ | C13H20N4O3S2 | 100 MG
Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG3) linker used for assembling antibody-drug conjugates (ADCs) and general bioconjugation. It contains an azide functional group enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN partners.
- Cleavable disulfide linker for controlled release.
- Azide-functionalized for CuAAC click chemistry.
- Compatible with SPAAC (DBCO and BCN) reactions.
- High purity suitable for conjugation workflows.
- Multiple pack sizes available for research use.
![eMolecules Broadpharm / m-PEG8-triethoxysilane / 250mg / 795361866 / BP-40222 / 95.000 / / [null] / 615.833 / C27H57NO12Si](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502472884.JPG-250.jpg)
eMolecules Broadpharm / m-PEG8-triethoxysilane / 250mg / 795361866 / BP-40222 / 95.000 / / [null] / 615.833 / C27H57NO12Si
Broadpharm / m-PEG8-triethoxysilane / 250mg / 795361866 / BP-40222 / 95.000 / / [null] / 615.833 / C27H57NO12Si
Medchemexpress LLC Fmoc-NH-PEG3-CH2CH2COOH | 867062-95-1 | 99.8% | 443.49 g/mol | C24H29NO7 | 5 G
Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected PEG3-based cleavable linker used for conjugation chemistry in research applications such as antibody-drug conjugates and PROTAC synthesis. It provides a short PEG spacer with an Fmoc-protected amino terminus and a terminal carboxylic acid for coupling reactions.
- High purity suitable for research use.
- PEG3 spacer provides solubility and flexibility.
- Fmoc protection enables standard amine deprotection workflows.
- Terminal carboxylic acid allows amide bond formation.
- Available in multiple pack sizes for synthesis scale-up.
Medchemexpress LLC BM-PEG3 | 86099-06-1 | 98.0% | 100 MG
BM-PEG3 is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling targeted degradation.
- PEG-based PROTAC linker
- For research use only
- Purity: 98.0%
- Molecular weight: 352.34
- Molecular formula: C16H20N2O7
- Appearance: White to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 100 mg/mL (in vitro)
- Solubility in 10% DMSO, 90% corn oil: ≥ 2.5 mg/mL (in vivo)
Medchemexpress LLC TFP-PEG3-TFP 50mg
TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]