Organometallic Compounds
![Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000210386.png-250.jpg)
Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG
m-PEG3-Tos is a tosyl-terminated polyethylene glycol (PEG) linker used as a reactive PEG3 spacer for conjugation and PROTAC synthesis. The tosyl leaving group enables nucleophilic substitution reactions to attach functional groups or linker arms in medicinal chemistry and bioconjugation workflows.
- Tosyl-terminated PEG3 linker for conjugation and PROTAC synthesis.
- Chemical name: 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate.
- CAS number: 62921-74-8.
- Molecular formula: C14H22O6S.
- Molecular weight: 318.39 g/mol.
- Purity: 98.8%.
- Package size: 500 MG.
Medchemexpress LLC 3,6,9,12,15-Pentaoxaheptadecane, 1,17-diazido- | 356046-26-9 | 100.0% | 332.36 | 250 MG
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. This product is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Reacts with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Reacts with molecules containing DBCO or BCN groups
Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | 97.0% | 751.42 | C38H59ClN4O7S | 1 G
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate designed as a building block for PROTAC synthesis and ligand-linker conjugate development in targeted protein degradation research. It contains an (S,R,S)-configured AHPC VHL ligand connected via a six-carbon PEG3 linker with a terminal chloro group to enable downstream conjugation.
- Useful as a VHL (E3 ligase) ligand building block for degrader design.
- C6-PEG3 linker provides flexibility and spacer length for bifunctional molecules.
- Terminal chloro group enables nucleophilic substitution or further functionalization.
- Characterized by analytical data including HPLC and LC-MS for batch confirmation.
- Provided as a solid suitable for synthetic chemistry workflows and storage under controlled conditions.
Medchemexpress LLC Boc-NH-PEG3-propargyl | 1333880-60-6 | 97.0% | C14H25NO5 | 100 MG
Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
Medchemexpress LLC m-PEG3-azide | 74654-06-1 | MFCD00020141 | >98% | C7H15N3O3 | 250 MG
m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in various cycloaddition reactions.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups.
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Medchemexpress LLC Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | 252881-73-5 | 303.3547 g/mol | C13H25N3O5 | 50 MG
N3-PEG3-CH2CH2-Boc is an azido-terminated PEG3 linker with a tert-butyl (Boc) protected carboxylic acid end, used as a cleavable PEG-based linker in antibody-drug conjugate and PROTAC synthesis, and as an azide reagent for click chemistry.
- Azide-terminated PEG3 linker suitable for click chemistry.
- tert-Butyl (Boc) protected carboxyl end for orthogonal deprotection.
- Used in ADC and PROTAC linker assembly.
- Available as a small pre-weighed laboratory pack for synthetic use.
Medchemexpress LLC (S)-17-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)-14-oxo-4,7,10-trioxa-13-azaoctadecane-1,18-dioic acid | 97.6% | C28H36N8O10 | 5 MG
Folate-PEG3-C2-acid is an acid fragment and PEG-type PROTAC linker used in the synthesis of Proteolysis-targeting Chimeras. It has a molecular weight of 644.63 and a purity of 97.56%.
- Stable under recommended storage conditions
- Consistent with structure based on 1H NMR Spectrum and LCMS
- Solid appearance
- For research use only
Medchemexpress LLC THP-PEG5-OH | 146395-14-4 | 25 MG
THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also described as a reference compound.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Reference compound
Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 100 MG
NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
Medchemexpress LLC Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | 60221-37-6 | 98.7% | 25 G
THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- High purity of 98.7%
- Molecular weight of 234.29
- Chemical formula is C11H22O5
- Appears as a liquid
- Colorless to light yellow
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 100 G
Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker
- Used in the synthesis of protacs
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports