Organometallic Compounds
Medchemexpress LLC I-PEG5-OH 100mg
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC HO-PEG3-(CH2)6-Cl | 1355955-95-1 | 95.0% | 268.78 g·mol⁻¹ | C12H25ClO4 | 10 MG
HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a 6-chlorohexyl group, designed for assembling PROTACs and other bifunctional molecules. It serves as a spacer to connect targeting ligands and E3 ligase binders in targeted protein degradation research and is supplied for research use only.
- Hydroxy-terminated PEG3 spacer with a 6-chlorohexyl terminus.
- Designed for synthesis of PROTACs and bifunctional conjugates.
- Molecular formula C12H25ClO4; molecular weight 268.78 g·mol⁻¹.
- CAS number 1355955-95-1 for unambiguous identification.
- Reported purity about 95% from suppliers' product listings.
- Supplied in small milligram-scale packages for research synthesis.
Medchemexpress LLC Bapta tetraethyl ester | 73630-07-6 | 588.65 | 250 MG
Bapta tetraethyl ester is a biochemical reagent primarily used as a cell-permeant calcium chelator in biological assays. It can cross cell membranes and is then hydrolyzed by intracellular esterases into its active form, BAPTA, to trap calcium within the cell. BAPTA is known for its high selectivity for calcium over other physiological ions, fast binding kinetics, and low pH sensitivity, making it suitable for buffering intracellular calcium concentrations without significantly affecting other ion levels.
- Biochemical reagent
- Used for research purposes only
- Cell-permeant calcium chelator
- High selectivity for calcium over other physiological ions
- Fast calcium binding kinetics
- Low pH sensitivity
- Buffers intracellular calcium concentrations
eMolecules 3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | 1204669-57-7 | MFCD27996217 | 1g
AstaTech | 3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | 1g | 410712794 | 75622 | 95.000 | 1204669-57-7 | MFCD27996217 | 513.066 | C12H11BrFIN6O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 100 MG
(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand that can be used for the synthesis of PROTACs. It is intended for research use only and is not for sale to patients. Its appearance is a solid, ranging from white to light yellow in color.
- VHL ligand
- Can be used for the synthesis of PROTACs
- Intended for research use only
- Solid, white to light yellow appearance
Medchemexpress LLC Bapta tetraethyl ester | 73630-07-6 | 588.65 | 1 G
Bapta tetraethyl ester is a biochemical reagent used in various research applications.
- For research use only
- Functions as a biochemical assay reagent
- Acts as a chelator
Medchemexpress LLC Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | 60221-37-6 | 98.7% | 25 G
THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- High purity of 98.7%
- Molecular weight of 234.29
- Chemical formula is C11H22O5
- Appears as a liquid
- Colorless to light yellow
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 1 G
Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate composed of a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. It can be utilized for the synthesis of PROTACs. This product is for research use only and not sold to patients.
- Molecular weight: 562.49
- Formula: C23H29F3N4O9
- Appearance: Solid-liquid mixture
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: 4°C, stored under nitrogen, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture).
Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 2 G
Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate, featuring a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is designed for the synthesis of PROTACs and is intended for research use only.
- Synthetic E3 ligase ligand-linker conjugate
- Features a Pomalidomide-based cereblon ligand and 3-unit PEG linker
- Utilized for the synthesis of PROTACs
- High purity: 99.0%
- Molecular weight: 562.49
- Chemical formula: C23H29F3N4O9
- Appears as a light yellow to yellow solid-liquid mixture
- Soluble in DMSO, ethanol, and water
- Offers multiple dissolution protocols for in vivo studies
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 100 MG
TBDMS-PEG3-OH is a tert-butyldimethylsilyl-protected PEG3-derived alcohol supplied for research use. It is used as a versatile linker and building block in medicinal chemistry, PROTAC synthesis, PEGylation, and drug-delivery conjugation, and is provided as a high-purity liquid suitable for synthetic applications.
- High purity (≥98.0%).
- Molecular weight 264.43 g/mol.
- Molecular formula C12H28O4Si.
- Suitable for linker and PEGylation chemistry.
- Available in small-scale packages for research (100 MG).
- For research use only; not for human use.
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 10 G
TBDMS-PEG3-OH is a polyethylene glycol (PEG) derivative used in chemical and pharmaceutical research, commonly as a linker or modifier in drug-delivery constructs and PROTAC synthesis. It is supplied as a colorless to light-yellow liquid and is typically provided at research-grade purity.
- Has a molecular weight of 264.43 g/mol.
- Chemical formula C12H28O4Si.
- CAS number 201037-95-8.
- Purity ≥98.0%.
- Supplied as a colorless to light-yellow liquid.
- Typical pack size 10 g.
- Useful as a PEG linker or modifier in drug-delivery and PROTAC synthesis.
Medchemexpress LLC Biotin-PEG3-OH | 1263044-40-1 | 98.0% | 375.48 g·mol⁻¹ | C16H29N3O5S | 5 MG
Biotin-PEG3-OH is a biotinylated polyethylene glycol (PEG3) linker designed for PROTAC synthesis and bioconjugation. It supplies a short, hydrophilic spacer with a terminal hydroxyl group and a biotin affinity handle for capture or detection in pull-down and labeling workflows.
- Biotin affinity tag for streptavidin-based capture and detection.
- PEG3 spacer provides hydrophilicity and flexible spacing.
- Terminal hydroxyl group enables further chemical modification.
- Available in small-scale quantities suitable for research workflows.
- Solid form with good solubility in DMSO for assay preparation.
Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 10 G
N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC DPC-681 | 284661-68-3 | 98.8% | 669.85 | 25 MG
DPC-681 is a potent and selective inhibitor of HIV protease. It is designed for research use only and not intended for patient use.
- Potent and selective inhibitor of HIV protease
- Active against wild-type HIV-1
- Retains potency against mutant HIVs with D30N mutation
- Shows minimal loss of potency against mutant variants with multiple amino acid substitutions
Medchemexpress LLC Azide-PEG3-Desthiobi 25mg
Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups