Solvents
Revvity Health Sciences Inc Iodine-125 Radionuclide, 5mCi, Specific Activity: ~17Ci/mg, 10-5M NaOH (pH 8-11)
Iodine-125 Radionuclide, 5mCi, Specific Activity: ~17Ci/mg, 10-5M NaOH (pH 8-11)
![Revvity Health Sciences Inc Nociceptin, [Leucyl-3,4,5-<sup>3</sup>H], 50µCi (1.85MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812323.jpg-250.jpg)
Revvity Health Sciences Inc Nociceptin, [Leucyl-3,4,5-3H], 50µCi (1.85MBq)
Nociceptin, [Leucyl-3,4,5-3H], 50µCi (1.85MBq)
Sigma Aldrich Fine Chemicals Biosciences Indole-3-acetic-2,2-d2 acid 98 atom % D, 98% (CP) | 24420-86-8 | MFCD01075447 | 100MG
Indole-3-acetic-2,2-d2 acid 98 atom % D, 98% (CP) | Purity: 98% (CP) | Mol Wt: 177.2 | 24420-86-8 | MFCD01075447 | 100MG
Medchemexpress LLC 7-keto-Deoxycholic acid | 911-40-0 | 99.7% | 406.56 | 50 MG
7-keto-Deoxycholic acid is a metabolite of bile acids found in *Clostridium absonum*. It can also be converted from *Lactobacillus* and *Bifidobacterium* under specific conditions. It shows an increasing bioconversion rate with the addition of an equimolar concentration of deoxycholic acid and is induced by deoxycholic acid and then metabolized. *E. lentum*-like c-25 converts 81.7% of 2 mM cholic acid to deoxycholic acid and 3.7% to 7-keto-Deoxycholic acid under anaerobic incubation. *E. lentum*-like c-25 also converts 91.5% of 150 mg/mL cholic acid to deoxycholic acid and 1.1% to 7-keto-Deoxycholic acid under anaerobic incubation.
- Metabolite of bile acids
- Found in Clostridium absonum
- Converted from Lactobacillus and Bifidobacterium
- Solid appearance
- White to off-white color
- Classified as ketones, aldehydes, and acids
- Endogenous metabolite
- Soluble in DMSO at 100 mg/mL
Apexbio Technology LLC Maraviroc(Synonyms: Selzentry, Celsentri, UK-427857, MVC), 10mM (in 1mL DMSO), CAS: 376348-65-1.
Maraviroc (CAS 376348-65-1) is a potent selective antagonist of the chemokine receptor CCR5 CCR5 functions as a coreceptor expressed on immune cells and facilitates entry of certain HIV-1 virus strains (R5-tropic) By binding CCR5 maraviroc effectively blocks HIV-1 envelope protein gp120 anchoring and consequently prevents viral fusion and subsequent cell entry In cellular assays with CCR5-tropic HIV-1 maraviroc demonstrates substantial antiviral activity (IC50 approximately 2 0 nM) and efficiently inhibits gp120-CCR5 interaction Maraviroc serves as a valuable research tool to explore CCR5-mediated viral entry and HIV tropism dynamics
Medchemexpress LLC SIS17 | 2374313-54-7 | 99.4% | 100 MG
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. It is intended for research use only.
- Mammalian histone deacetylase 11 (HDAC 11) inhibitor
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other histone deacetylases
- Suitable for research use
- Inhibits HDAC11 with an IC50 value of 0.83 μM
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Exhibits synergistic cytotoxicity in K562 cells when combined with Oxaliplatin
Chemscene ChemScene | 2-(3,5-Dimethylphenyl)acetic acid | 10G | CS-W016090 | 0.98 | 42288-46-0| MFCD00082776 | 164.2
ChemScene | 2-(3,5-Dimethylphenyl)acetic acid | 10G | CS-W016090 | 0.98 | 42288-46-0| MFCD00082776 | 164.2
Genscript Corporation 25-OH Vitamin D3 HRP Conjugat
Vitamin D plays an important role in calcium homeostasis and metabolism Vitamin D3 and vitamin D2 are two forms of vitamin D in human body both of which only a few foods contain The deficiency of vitamin D in human body can cause a threat of diseases such as osteomalacia rickets and diabetes 25-OH Vitamin D2 and 25-OH Vitamin D3 as vitamin D metabolites are measured in human serum to evaluate vitamin D level Vitamin D supplements are considered as an effective way to treat or to prevent the diseases
Aqua Solutions Mobile Phase Acetonitrile, Methanol, Water (4L)
Mobile Phase Acetonitrile, Methanol, Water (4L)
Apexbio Technology LLC LY2157299(Synonyms: Galunisertib, LY-2157299, LY2157299 monohydrate, LY2157299 hydrate, LY2157299 free base), 10mM (in 1mL DMSO), CAS: 700874-72-2.
LY2157299 (CAS 700874-72-2) is a small-molecule antagonist that selectively targets the transforming growth factor-beta type I receptor (T RI) By blocking signaling through T RI it prevents phosphorylation of downstream effectors Smad2 and Smad3 thereby interfering with the TGF- signaling pathway Preclinical studies indicate LY2157299 inhibits 1-integrin activation reduces tumor cell invasion lowers connective tissue growth factor (CTGF) production and suppresses angiogenesis Currently in phase II clinical trials LY2157299 is being investigated primarily for therapeutic potential against hepatocellular carcinoma and glioblastoma
Medchemexpress LLC Risdiplam-d4 | 1825352-65-5 | 98.9% | 405.49 | 100 MG
Risdiplam-d4 is a deuterium-labeled version of Risdiplam. Risdiplam (RG7916) is an orally administered SMN2 pre-mRNA splicing modifier that is distributed both centrally and peripherally, and it works by increasing survival motor neuron (SMN) protein levels.
- This compound can be used as a tracer.
- It can serve as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
![Revvity Health Sciences Inc ATP, [γ-<sup>32</sup>P]- 3000Ci/mmol 5mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810382.jpg-250.jpg)
Revvity Health Sciences Inc ATP, [γ-32P]- 3000Ci/mmol 5mCi/ml EasyTide, 250 µCi
ATP, [γ-32P]- 3000Ci/mmol 5mCi/ml EasyTide, 250 µCi
eMolecules 2-(2-Propynyloxy)benzenecarbaldehyde | 29978-83-4 | 500MG
Matrix Scientific | 2-(2-Propynyloxy)benzenecarbaldehyde | 500MG | 29978-83-4 | MFCD06739289 | MW:156.61
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Medchemexpress LLC Dodecanoic-2,2-d2 acid | 64118-39-4 | MFCD00053326 | 99.8% | 202.33 | C12H22D2O2 | 100mg
Lauric acid-d2 is the deuterium labeled Lauric acid Lauric acid is a middle chain-free fatty acid with strong bactericidal properties The EC50s for P acnes S aureus S epidermidis are 2 6 4 g/mL respectively