Glycosyl compounds
Medchemexpress LLC D-2-amino-5-phosphonovaleric acid | 79055-68-8 | MFCD00078839 | 99.9% | 197.13 g/mol | C5H12NO5P | 1 MG
D-AP5 is a selective, competitive antagonist of NMDA-type ionotropic glutamate receptors. It binds the glutamate recognition site to inhibit NMDA receptor-mediated synaptic transmission and is widely used in neuroscience research for studying excitatory signaling and synaptic plasticity.
- Selective, competitive NMDA receptor antagonist.
- Suitable for in vitro and in vivo studies of NMDA-mediated signaling.
- Solubility: water soluble (~2 mg/mL with ultrasonic); poor solubility in DMSO and ethanol.
- Storage: powder stable at -20°C for up to 3 years; store solutions at -80°C for long term.
- Includes molecular and identifier data to ensure accurate compound selection.
Medchemexpress LLC Isrib (trans-isomer) | 1597403-47-8 | 99.49% | 451.34 | 50 MG
ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. It effectively reverses the effects of eIF2α phosphorylation and reduces the viability of cells subjected to PERK-activation by chronic endoplasmic reticulum stress. This trans-isomer is 100-fold more potent than cis-ISRIB, demonstrating stereospecific interaction with its cellular target.
- Potently reverses eIF2α phosphorylation (IC50=5 nM)
- Blocks eIF2α phosphorylation-induced stress granule (SG) formation
- Increases long-term memory in rodents
- Readily crosses the blood-brain barrier
Medchemexpress LLC KI696 isomer | 1799974-69-8 | 99.3% | 550.63 | C28H30N4O6S | 25 MG
KI696 isomer is the less active stereoisomer of KI696, a high-affinity probe that disrupts the Keap1-NRF2 interaction. Supplied as a white to off-white solid for research use, it is offered in solid and DMSO solution formats; follow recommended storage conditions for stability.
- Less active stereoisomer that disrupts the Keap1-NRF2 interaction.
- High purity (99.3%).
- White to off-white solid physical form.
- Molecular formula C28H30N4O6S; molecular weight 550.63.
- Available as solids and 10 mM solutions in DMSO.
- Store powder at -20°C and solutions at -80°C for long-term stability.
Medchemexpress LLC D-α-Tocopherylquinone | 7559-04-8 | 5 MG
D-α-Tocopherylquinone is a quinone isolated from *Phaeodactylum tricornutum* and an oxidation product of α-Tocopherol (vitamin E). It functions as an anticoagulant and antioxidant, actively reducing cellular oxidative damage caused by oxidized lipids. The compound binds to a liver cytosolic protein (molecular mass ~40 kDa) and to glutathione-S-transferase (GST), which aids its transport to metabolism sites or excretion in bile.
- Isolated from *Phaeodactylum tricornutum*
- Oxidation product of α-tocopherol (vitamin E)
- Acts as an anticoagulant
- Acts as an antioxidant
- Reduces cellular oxidative damage from oxidized lipids
- Binds to a liver cytosolic protein
- Binds to glutathione-S-transferase (GST)
- Facilitates transport for metabolism or excretion
- Inhibits GST activity dose-dependently
TARGETMOL CHEMICALS INC beta-Glucogallin 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. beta-Glucogallin (beta-Glucogallin) is a selective aldose reductase (AKR1B1) inhibitor with antioxidant, anti-glycation, and anti-inflammatory properties. beta-Glucogallin is a naturally occurring compound derived from Emblica officinalis and is used in diabetes research. Vitamin B3-d4 Purity 99.14%
Sigma Aldrich Fine Chemicals Biosciences 4-Nitrophenyl beta-D-fucoÂpyranÂoside >=98% (TLC) | 1226-39-7 | MFCD00040651 | 100MG
4-Nitrophenyl beta-D-fucoÂpyranÂoside >=98% (TLC) | Purity: >=98% (TLC) | Mol Wt: 285.25 | 1226-39-7 | MFCD00040651 | 100MG
Medchemexpress LLC D-α-hydroxyglutaric acid disodium | 103404-90-6 | MFCD00069573 | 98.0% | 192.08 g/mol | C5H6Na2O5 | 1 ML
D-α-hydroxyglutaric acid disodium is the disodium salt of the D-enantiomer of 2-hydroxyglutaric acid, provided as a 10 mM solution (1 mL) or as solids. It is used as a biochemical research reagent to probe α-ketoglutarate-dependent enzymes, metabolic and mitochondrial function, and oncometabolite biology. Purity is typically 98.0%.
- Available as 10 mM solution in water (1 mL) or as solid quantities for flexibility.
- Useful for studies of α-ketoglutarate-dependent dioxygenases and epigenetic modifiers.
- Reported to increase reactive oxygen species and inhibit ATP synthase and mTOR signaling.
- High purity (98.0%) suitable for biochemical and cellular assays.
- Documents provided for quality and safety: data sheet, COA, and SDS.
Cayman Chemical n-Dodecyl-a-D-maltosIde 500mg
A nonionic detergent commonly used to solubilize integral membrane proteins and protein complexes; CMC = 0.15 mM; has been used to solubilize PSI and PSII complexes from plant thylakoid membranes, as well as intact grana
Medchemexpress LLC 2-(5-Phenyl-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-N-(5-phenylpyridin-2-yl)acetamide | 2074607-48-8 | 99.8% | 432.48 g·mol⁻1 | C26H20N6O | 25 MG
A potent small-molecule Porcn inhibitor for research use that blocks Wnt protein secretion and downstream signaling. It exhibits an EC50 of 80 pM in L-Wnt-STF cells and suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays. Supplied as a high-purity solid or as a 10 mM solution in DMSO for experimental convenience.
- Potent Porcn inhibition with an EC50 of 80 pM in L-Wnt-STF cells.
- Blocks secretion of Wnt proteins and downstream signaling pathways.
- Suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays.
- High purity (≈99.8%) suitable for biochemical and cellular studies.
- Available as solid quantities (including 25 mg) and as a 10 mM solution in DMSO.
- Recommended storage: solid at 4°C; in solvent at -80°C for long-term stability.
Medchemexpress LLC Physion 8-O-β-D-glucoside | 26296-54-8 | 5 MG
Physion 8-O-β-D-glucoside is a bioactive component derived from Fallopia multiflora. It is utilized in the research of dizziness and is intended for research use only, not for patient treatment.
- Molecular weight: 446.40
- Formula: C22H22O10
- Appearance: Yellow to orange solid
- Purity: 98.0%
- Used for dizziness research
- Bioactive component of Fallopia multiflora
- For research use only