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Filtered Search Results
Medchemexpress LLC Glucose 6 phosphate dehydrogenase antibody (YA411, rabbit) | 10 UL
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Glucose 6 phosphate dehydrogenase antibody (YA411) is a rabbit-derived and non-conjugated IgG monoclonal antibody that targets glucose 6 phosphate dehydrogenase.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets glucose 6 phosphate dehydrogenase
- Applications include metabolism-sugar/lipid metabolism
- Antibody host is rabbit
- Target is endogenous metabolite; GLUT
- Antibody isotype is IgG
- Antibody type is primary antibody; recombinant
- Stored at -20°C for 1 year
- Shipped on blue ice
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Medchemexpress LLC Calcium disodium edetate hydrate | 23411-34-9 | MFCD00149454 | 98.0% | 410.3 g·mol⁻¹ | C10H16CaN2Na2O10 | 500 MG
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Calcium disodium edetate hydrate is the calcium disodium salt of ethylenediaminetetraacetic acid (EDTA). It is a metal-chelating reagent for life-science and analytical workflows, used to sequester divalent and trivalent metal ions and to control metal availability in assays and buffer systems.
- Purity 98.0%.
- White to off-white solid, hydrate form.
- Effective chelator of Ca2+, Pb2+, Cd2+, and other metal ions.
- Useful for buffer preparation and metal sequestration in biochemical assays.
- Available in common laboratory pack sizes including 500 MG.
- Store sealed away from moisture and light; recommended 4°C for solids.
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Medchemexpress LLC Crocetin (disodium) | 591230-99-8 | 99.3% | 372.37 | 1 ML
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Crocetin disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. It is a saffron metabolite originating from the crocin apocarotenoids and has been shown to exert strong NMDA receptor affinity, which is thought to be responsible for the CNS activity of saffron. This solid, orange to reddish brown compound is for research use only.
- Acts as an NMDA receptor antagonist with high affinity.
- Derived from saffron (Crocus sativus L.) and is a saffron metabolite.
- Responsible for CNS activity of saffron.
- Soluble in H2O: ≥ 4.56 mg/mL (12.25 mM).
- Solid appearance, orange to reddish brown color.
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Medchemexpress LLC Lometrexol disodium | 120408-07-3 | 98.0% | 487.42 | C21H23N5Na2O6 | 5 MG
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Lometrexol disodium is an antipurine antifolate research compound that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and serine hydroxymethyltransferase 1/2 (hSHMT1/2), disrupting de novo purine synthesis and leading to cell cycle arrest and apoptosis. It is supplied as a disodium salt for biochemical and cellular studies.
- Potent GARFT and hSHMT1/2 inhibitor used to study purine metabolism.
- High purity: 98.0% suitable for analytical and biological assays.
- Molecular formula C21H23N5Na2O6 and molecular weight 487.42.
- Provided as a solid powder in small research pack sizes for convenience.
- Documentation available: data sheet, certificate of analysis, and safety data sheet.
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Medchemexpress LLC Cyclic GMP-AMP (disodium); 3',3'-cGAMP (disodium) | 2407516-83-8 | 98.47% | 718.37 | 1 MG
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cGAMP disodium is an endogenous second messenger that triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), leading to a signaling cascade that produces type I interferons and other immune mediators. This product is suitable for various research applications.
- Promotes antigen-specific proliferation capacity of spleen cells
- Directly activates murine and human dendritic cells in vitro
- Increases transcription of IFNB1 in stimulated fibroblasts
- Induces an antiviral state and type I IFN secretion by activating ER-resident receptor STING
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Apexbio Technology LLC Pamidronate Disodium 57248-88-1 50mg
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Pamidronate Disodium (CAS 57248-88-1) is a small-molecule inhibitor targeting osteoclastic bone resorption It is designed to inhibit osteoclast-mediated bone degradation thereby regulating bone metabolism Pamidronate Disodium exerts its biological activity primarily through selective binding to hydroxyapatite crystals in bone followed by suppression of osteoclast activity and induction of osteoclast apoptosis In in vitro studies Pamidronate Disodium demonstrates inhibitory activity on osteoclastic bone resorption with an IC50 in the micromolar range (varying according to experimental conditions) Based on these pharmacological properties Pamidronate Disodium holds research potential in studies of bone density disorders osteoporosis hypercalcemia of malignancy and metastatic bone diseases
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Medchemexpress LLC ERRα Ligand-Linker Conjugates 1 | 98.8% | 50 MG
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ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. It can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1. This product is for research use only.
- Incorporates a ligand for estrogen-related receptor alpha (ERRα)
- Includes a PROTAC linker
- Recruits E3 ligases MDM2
- Can be used in the synthesis of PROTACs
- For research use only
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Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 50X1ml.
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Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
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Medchemexpress LLC Lometrexol disodium | 120408-07-3 | 98.0% | C21H23N5Na2O6 | 1 MG
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Lometrexol disodium is an antipurine antifolate that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and human Serine hydroxymethyltransferase1/2 (hSHMT1/2). This leads to the inhibition of de novo purine synthesis, causing abnormal cell proliferation, apoptosis, and cell cycle arrest, thus exhibiting anticancer activity.
- Inhibits purine synthesis.
- Induces cell apoptosis.
- Causes cell cycle arrest.
- Demonstrates anticancer properties.
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Selleck Chemical LLC Fosfomycin Disodium S5048-1g
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Fosfomycin (Phosphonemycin) is a bactericidal low-molecular weight broad-spectrum antibiotic with putative activity against several bacteria including multidrug-resistant Gram-negative bacteria by irreversibly inhibiting an early stage in cell wall synthesis
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Selleck Chemical LLC Pemetrexed Disodium Hydrate
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Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS DHFR and GARFT with Ki of 1 3 nM 7 2 nM and 65 nM respectively Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis
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Medchemexpress LLC Piperaquine phosphate | 85547-56-4 | 98.6% | 5 MG
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Piperaquine phosphate is an antimalarial bisquinoline agent primarily used in antimalarial research. It is often studied in combination with Artemisinin.
- Used in antimalarial research.
- Acts as a bisquinoline antimalarial agent.
- Can be combined with Artemisinin for research purposes.
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Gold Biotechnology Inc EDTA Disodium dihydrate 500 g
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EDTA (Ethylenediaminetetraacetic acid) is a chelating agent a general chemical and a sequestrant In molecular biology applications it is used to minimize metal ion contamination and prevent enzymatic activity
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Apexbio Technology LLC Phosphatase Inhibitor Cocktail (1 Tube, EDTA-Free, 100X)(Synonyms: Phosphatase Inhibitor Cocktail, Phosphatase Inhibitor Mix, Phosphatase Inhibitor Set), 100X1ml.
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Phosphatase Inhibitor Cocktail (1 Tube EDTA-Free 100X) provides comprehensive inhibition of various phosphatases including acid and alkaline phosphatases serine/threonine phosphatases (e g PP1 PP2A PP2B) and protein tyrosine phosphatases (PTPs) By suppressing phosphatase enzymatic activities it preserves phosphorylation states of proteins in lysates from mammalian plant yeast insect or bacterial samples ensuring more accurate downstream analysis It is applicable in protein lysate preparations immunoprecipitations nuclear extracts and processing of fixed tissues (e g FFPE) to maintain phosphorylation modifications
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Medchemexpress LLC Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate | 29932-54-5 | MFCD03414198 | 99.0% | 430.56 g/mol | C10H20MgN2Na2O12 | 100 G
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Magnesium disodium EDTA tetrahydrate is the magnesium salt of ethylenediaminetetraacetic acid used as a chelating reagent in biochemical and analytical applications. It binds divalent and trivalent metal ions, functions as a reversible activator of fructose diphosphatase, and is supplied as a high-purity solid suitable for laboratory assays and metal-ion control.
- High purity (≈99.0%) suitable for analytical use.
- Effective chelator of divalent and trivalent metal ions.
- Reversible activator of fructose diphosphatase in biochemical assays.
- Solid, easy-to-weigh tetrahydrate form for reproducible results.
- Available in convenient laboratory pack sizes.
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