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Filtered Search Results
Gold Biotechnology Inc EDTA Disodium dihydrate 1 kg
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EDTA (Ethylenediaminetetraacetic acid) is a chelating agent a general chemical and a sequestrant In molecular biology applications it is used to minimize metal ion contamination and prevent enzymatic activity
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Medchemexpress LLC Retagliptin phosphate | 1256756-88-3 | 99.7% | 562.36 | 100 MG
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Retagliptin phosphate is a selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It can be used for research related to type 2 diabetes mellitus (T2DM). This compound inhibits the degradation of GLP-1, thereby amplifying the incretin effect.
- Selective, competitive, and orally active
- Inhibits dipeptidyl peptidase-4 (DPP-4)
- For type 2 diabetes mellitus (T2DM) research
- Inhibits degradation of GLP-1
- Amplifies the incretin effect
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Medchemexpress LLC Eprodisate disodium | 36589-58-9 | 98.0% | 500 MG
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Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate. It is a negatively charged sulfonated inhibitor of fibrillogenesis that can be used in the treatment of amyloid A (AA) amyloidosis.
- Orally available disodium salt form of Eprodisate.
- Negatively charged sulfonated inhibitor of fibrillogenesis.
- Used in treatment of amyloid A (AA) amyloidosis.
- Targets Amyloid-β.
- Involves Neuronal Signaling pathway.
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Cayman Chemical UDPsodIum salt hydrate 500mg
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The diphosphate of uridine; a specific agonist of the P2Y purinoceptor P2Y6 (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction; an antagonist of P2Y14
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Medchemexpress LLC Ethylenediaminetetraacetic acid (disodium) | 139-33-3 | MFCD00070672 | 93.5% | 336.21 g·mol⁻1 | C10H14N2Na2O8 | 50 MG
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EDTA disodium is the disodium salt of ethylenediaminetetraacetic acid, a commonly used chelating agent and analytical reagent for biochemical and analytical workflows. Supplied as a solid standard, it is suitable for metal ion chelation, sample preparation, and method calibration in laboratory applications.
- Chelates divalent and trivalent metal ions.
- Serves as an analytical standard for calibration and validation.
- Suitable for biochemical assays and sample preparation.
- Available in small, laboratory-scale quantities for convenience.
- Reported purity approximately 93.5% for the standard material.
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Medchemexpress LLC N-(2-carboxyphenyl)-4-chloroanthranilic acid disodium salt | 64808-48-6 | MFCD00941422 | 99.9% | 335.65 | C14H8ClNNa2O4 | 100 MG
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Lobenzarit disodium is the disodium salt form of lobenzarit, an immunomodulatory compound with anti-arthritic and antioxidative activity. Supplied as a high-purity solid for research use, it is used in studies of immune modulation, inflammation, and oxidative stress, and is suitable for formulation in aqueous media for in vitro and exploratory in vivo work.
- High purity suitable for research applications.
- Molecular weight 335.65 for accurate dosing calculations.
- Disodium salt form improves water solubility and handling.
- Available in multiple small package sizes for dose flexibility.
- Commonly used in immunomodulation and anti-arthritic studies.
- Provided with batch-specific certificate of analysis.
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Medchemexpress LLC Lometrexol disodium | 120408-07-3 | MFCD00239212 | 98.0% | C21H23N5Na2O6 | 10MG
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Lometrexol disodium is an antifolate research reagent that inhibits glycinamide ribonucleotide formyltransferase (GARFT), disrupting de novo purine biosynthesis. Supplied as the disodium salt, it is intended for laboratory research use.
- Purity 98.0%.
- Chemical formula C21H23N5Na2O6.
- Molecular weight 487.42 g/mol.
- Appearance solid, white to light yellow.
- Available pack sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
- Research applications include study of purine biosynthesis inhibition.
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Selleck Chemical LLC Clodronate Disodium S4108-1g
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Clodronate Disodium a bisphosphonate is a potent antiosteolytic agent which inhibits bone resorption
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Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 98.0% | 503.42 | 50 MG
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NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases, with IC50 values of 0.318 μM and 0.355 μM for Shp2 and Shp1, respectively. It also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Inhibits dual-specificity phosphatase 26 (DUSP26)
- Inhibits DUSP26 function in NB cell lines
- Results in increased p53 phosphorylation and activation
- Possesses excellent anti-neuroblastoma activity in vivo
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Medchemexpress LLC Sitagliptin (phosphate) | 654671-78-0 | 99.6% | 505.31 | 1 ML
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Sitagliptin (MK-0431) phosphate is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. It blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (Kᵢ = 1 nM), thereby increasing the level of active incretin. Sitagliptin phosphate can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, independent of DPP-4. It shows protective effects on pancreatic islet grafts in type 1 diabetes models and can be used for the study of type 1 and type 2 diabetes.
- Orally active and highly selective DPP4 inhibitor
- Blocks degradation of GLP-1 and GIP
- Increases active incretin levels
- Directly stimulates GLP-1 secretion
- Protective effects on pancreatic islet grafts
- Useful for type 1 and type 2 diabetes research
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Sigma Aldrich Fine Chemicals Biosciences L-Rhamnose natural sourced, 99%, FG | 10030-85-0 | MFCD00149363 | 10KG
L-Rhamnose natural sourced, 99%, FG | Purity: 99% | Mol Wt: 182.17 | 10030-85-0 | MFCD00149363 | 10KG
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Medchemexpress LLC D-Glucose 6-phosphate sodium | 54010-71-8 | 98.0% | 282.12 | 5 G
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D-Glucose 6-phosphate sodium is an endogenous metabolite used for research purposes. It is not sold to patients.
- Endogenous metabolite
- For research use only
- Human endogenous metabolite
- Solid appearance
- White to off-white color
- Soluble in H2O (50 mg/mL)
- Store at 4°C under nitrogen
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Crescent Chemical Co Inc GLUCOSE ANHYDROUS
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Glucose anhydrous analytical grade Assay (titr.)Water (loss on drying) min. 99.5 %max. 0.5 % Size - 100G Storage Conditions - +15 °C TO +30 °C Catalog Number - 22700.01 CAS 50-99-7
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Medchemexpress LLC D-Glucose pentaacetate | 83-87-4 | 99.9% | 390.34 | 1 G
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D-Glucose pentaacetate is a sugar opening ring. It is for research use only and not intended for sale to patients.
- For research use only.
- Solid appearance.
- White to off-white color.
- Ships at room temperature in continental US; may vary elsewhere.
- Store powder at -20°C for 3 years; 4°C for 2 years.
- Store in solvent at -80°C for 6 months; -20°C for 1 month.
- Soluble in DMSO (200 mg/mL), requires ultrasonic, hygroscopic DMSO significantly impacts solubility, use newly opened DMSO.
- Stock solution storage: -80°C for 6 months; -20°C for 1 month.
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Medchemexpress LLC β-D-Glucose pentaacetate (Penta-O-acetyl-β-D-glucopyranose) | 604-69-3 | 98.0% | 390.34 | 50 G
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β-D-Glucose pentaacetate (Penta-O-acetyl-β-D-glucopyranose) is a glucose derivative primarily used to explore the mechanism of insulin secretion. In cellular assays, it showed an IC50 of > 200 μM against human A549, DU-145, HeLa, MCF7, and NIH3T3 cells after 48 hours. In vitro, it is slightly less potent than α-D-Glucose Pentaacetate in stimulating insulin secretion.
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