Monosaccharides
Medchemexpress LLC Baricitinib phosphate | 1187595-84-1 | MFCD25976707 | 100.0% | 469.41 g/mol | C16H20N7O6PS | 10 MG
Baricitinib phosphate is the phosphate salt form of baricitinib, a selective, orally bioavailable inhibitor of JAK1 and JAK2 with low-nanomolar potency. It is supplied as a solid research reagent intended for in vitro and in vivo studies probing JAK-mediated signaling.
- Selective inhibitor of JAK1 and JAK2 (IC50: JAK1 5.9 nM; JAK2 5.7 nM; TYK2 53 nM; JAK3 560 nM).
- Molecular formula C16H20N7O6PS and molecular weight 469.41 g/mol.
- CAS number 1187595-84-1.
- Purity 99.97% as listed by manufacturer.
- High solubility in DMSO (250 mg/mL; 532.58 mM); in vivo formulations show solubility ≥2.08 mg/mL (4.43 mM).
- Appearance white to yellow solid suitable for research use.
- Store sealed at 4°C; in solvent store at -80°C (1 year) or -20°C (6 months).
Apexbio Technology LLC EPRODISATE-DISODIUM-100MG
Eprodisate disodium (CAS No 36589-58-9) is a compound studied primarily within the field of biomedical research It originates as a synthetic molecule designed for therapeutic intervention in amyloid-related diseases Eprodisate disodium functions by inhibiting the polymerization of amyloid fibrils specifically targeting the interaction between amyloid proteins and glycosaminoglycans which are crucial pathways in disease progression Its activity is commonly observed in the nanomolar to low micromolar range indicating potent efficacy The compound is frequently utilized in cell models and animal studies for investigating amyloid inhibition and can be instrumental in drug screening processes Experimental concentrations typically depend on the specific research design Such studies aim to validate its potential as a therapeutic agent enhancing the understanding of diseases characterized by amyloid accumulation
Medchemexpress LLC Glucose-6-phosphate dehydrogenase | 9001-40-5 | 108.6 kDa | 5KU
Glucose-6-phosphate dehydrogenase (G6PD) from a microorganism is the rate-limiting enzyme of the pentose phosphate pathway. Supplied as an enzymatic preparation (5 KU), it generates NADPH for biochemical and enzymatic assays and is intended for research applications including metabolic studies, antioxidant pathway analysis, and disease models such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy. Refer to the product data sheet and certificate of analysis for purity, storage, and handling instructions.
- Rate-limiting enzyme of the pentose phosphate pathway.
- Provides NADPH for antioxidant and metabolic assays.
- Enzyme activity ≥150 U/mg (solid).
- Specific activity ≥500 U/mg (protein).
- Unit definition: 1 μmol D-glucose 6-phosphate oxidized per min at pH 7.8, 37°C.
- Pack size: 5 KU.
- Source organism: microorganism.
- Purity and storage details available in data sheet and certificate of analysis.
Medchemexpress LLC D-xylulose 5-phosphate sodium | 105931-44-0 | MFCD00070073 | 95.0% | 252.09 g/mol | C5H10NaO8P | 5mg
D-Xylulose 5-phosphate (sodium) is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway D-xylulose-5-phosphate can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae) with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system[1]
Medchemexpress LLC Pemetrexed disodium | 150399-23-8 | MFCD07779402 | 99.8% | 471.37 g·mol⁻¹ | C20H19N5Na2O6 | 1 ML
Pemetrexed disodium is the disodium salt of pemetrexed, an antifolate antimetabolite used in research. Supplied as a ready-to-use 10 mM solution (1 mL) in water, this reagent is intended for biochemical and cell-based assays and analytical applications.
Apexbio Technology LLC Demethylcantharidate-disodium
Demethylcantharidate disodium (CAS No 129-67-9) is a compound studied in the context of biomedical research specifically in pharmacological studies It originates from the traditional toxin cantharidin and operates by inhibiting protein phosphatases impacting pathways involved in cell growth and apoptosis Its in vitro activity is usually observed in the nanomolar to low micromolar range This compound is commonly applied in various cell models animal studies and drug screening protocols to explore its potential therapeutic effects Experimental concentrations typically depend on the specific research design