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Filtered Search Results
Selleck Chemical LLC TL13-112-E1846-100MG
TL13-112 is a degrader of anaplastic lymphoma kinase (ALK) with an IC50 of 0 60 nM It demonstrates anti-proliferative activity in non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphoma (ALCL) cell lines
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Selleck Chemical LLC TL13-112-E1846-5MG
TL13-112 is a degrader of anaplastic lymphoma kinase (ALK) with an IC50 of 0 60 nM It demonstrates anti-proliferative activity in non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphoma (ALCL) cell lines
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Cambridge Isotope Laboratories Mono-n-octyl phthalate (ring-1 2-13C2 dicarboxyl-13C2 99%) 100 ug/mL in MTBE 1 2 mL
Mono-n-octyl phthalate (ring-1 2-13C2 dicarboxyl-13C2 99%) 100 ug/mL in MTBE 1 2 mL
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Apexbio Technology LLC Oxytocin acetate 6233-83-6 50mg
Oxytocin acetate (CAS 6233-83-6) is an acetate salt form of oxytocin a neuropeptide synthesized primarily in hypothalamic regions including the paraventricular and supraoptic nuclei Biologically oxytocin acts as a positive allosteric modulator of the -opioid receptor (MOR) enhancing receptor-mediated signaling without directly activating MOR or altering opioid ligand affinity In vitro studies with hMOR-expressing HEK293 cells indicate oxytocin augments signaling induced by MOR agonists such as endomorphin-1 morphine and fentanyl Its intracerebroventricular administration increases neuronal activity in rat nucleus accumbens shell highlighting potential roles in pain modulation social behavior and addiction research
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Apexbio Technology LLC Bradykinin (acetate) 6846-03-3 10mg
Bradykinin acetate (CAS 6846-03-3) is a peptide agonist targeting G protein-coupled B1 and B2 receptors It is designed to activate bradykinin receptors thereby modulating inflammatory responses vascular tone and endothelial signaling pathways Bradykinin acetate exerts its biological activity primarily through endothelium-dependent release of nitric oxide and prostacyclin leading to vasodilation Receptor activation also triggers non-vascular smooth muscle contraction increases vascular permeability and mediates pain signaling pathways Based on these pharmacological properties Bradykinin acetate holds research potential in studies of inflammation pain mechanisms and endothelial cell signaling
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Apexbio Technology LLC Ulipristal acetate 126784-99-4 50mg
Ulipristal acetate (126784-99-4) is a selective progesterone receptor modulator (SPRM) targeting progesterone receptors It is designed to modulate receptor-mediated signaling thereby regulating endometrial tissue proliferation and fibroid cell growth Ulipristal acetate exerts its biological activity primarily through reversible inhibition of progesterone-dependent signaling pathways Based on these pharmacological properties ulipristal acetate holds research potential in studies of progesterone signaling pathways uterine physiology hormonal regulation mechanisms and benign gynecological conditions such as uterine myoma
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Apexbio Technology LLC Leuprolide Acetate(Synonyms: GnRH receptor agonist, Gonadotropin-Releasing Hormone receptor agonist, GnRH agonist), 10mg, CAS: 74381-53-6.
A3551 is a small molecule compound designed to modulate specific cellular signaling pathways implicated in various pathological states It functions primarily by targeting kinase-mediated pathways thereby influencing intracellular signaling cascades associated with cell proliferation and differentiation Due to its pathway-specific mechanism of action A3551 is valuable for biomedical research examining signal transduction mechanisms oncogenesis processes and potential therapeutic intervention strategies
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Apexbio Technology LLC Abiraterone acetate 154229-18-2 50mg
Abiraterone acetate (CAS 154229-18-2) is the 3 -acetate ester prodrug of abiraterone a steroidal inhibitor of androgen biosynthesis Abiraterone selectively and irreversibly inhibits cytochrome P450 17 -hydroxylase/17 20-lyase (CYP17) an enzyme critical for the synthesis of androgen and cortisol This inhibition occurs via covalent binding and is characterized by a reported IC50 of 72 nM Abiraterone s potency attributed to its 3-pyridyl substituent exceeds that of ketoconazole by 10- to 30-fold in CYP17 inhibition Abiraterone acetate is widely used in research exploring mechanisms and interventions for castration-resistant prostate cancer
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Medchemexpress LLC Anecortave acetate 10mg | 7753-60-8 | 386.5 g/mol | C23H30O5 | 10 MG
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Anecortave acetate is a steroidal angiostatic agent used in research on ocular neovascularization and age-related macular degeneration. It is supplied as a high-purity research reagent with supporting analytical documentation and handling guidance.
- High reported purity, suitable for research use.
- Molecular weight 386.5 g/mol and formula C23H30O5.
- Available in a 10 mg research package.
- Analytical documentation available, including COA, HNMR, and LCMS.
- Used in studies of angiogenesis and retinal neovascular disorders.
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Medchemexpress LLC 1-O-n-Octyl-B-D-gluc 5mg | 129522-81-2 | 5 MG
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1-O-n-Octyl-β-D-glucopyranoside-d17 (CAS 129522-81-2) is a deuterium-labeled n-octyl β-D-glucopyranoside used as a non-ionic surfactant and analytical tracer in biochemical and biophysical research. Supplied as a solid in small mass packaging for analytical and tracer studies.
- Deuterium-labeled n-octyl β-D-glucopyranoside for tracer applications.
- Non-ionic surfactant useful for membrane protein solubilization.
- Provided as a solid in small-mass packaging suitable for analytical workflows.
- Molecular weight 309.47 g·mol⁻¹ and formula C14H11D17O6.
- Documentation available: data sheet and safety data sheet on request.
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Medchemexpress LLC Octyl-a-ketoglutarat 5mg | 876150-14-0 | 5 MG
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Octyl-α-ketoglutarate is a cell-permeable ester of α-ketoglutarate used in biochemical and cellular research to modulate HIF signaling and prolyl hydroxylase activity. It is used to probe metabolism, demethylation, and TCA cycle dysfunction in cell-based assays.
- Cell-permeable ester of α-ketoglutarate suitable for cell-based assays.
- Stimulates prolyl hydroxylase (PHD) activity and modulates HIF signaling.
- Useful for studies of metabolism, demethylation, and TCA cycle dysfunction.
- Available in small milligram quantities for research use.
- Provided with quality documentation and testing.
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Medchemexpress LLC Helenalin acetate 1mg | 10180-86-6 | 304.34 g/mol | 1 MG
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Helenalin acetate is a sesquiterpene lactone research compound that acts as a natural NF-κB inhibitor and a potent C/EBPβ inhibitor with reported anti-inflammatory and anticancer activity. It is supplied as a solid (white to off-white) at high purity for use in biochemical and cell-based studies.
- Acts as an NF-κB inhibitor and potent C/EBPβ inhibitor.
- Reported anti-inflammatory and anticancer activity.
- High purity (99.55%) suitable for research applications.
- Supplied in small-mass pack sizes for assay-scale experiments.
- Store protected from light at -20°C; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Orbofiban acetate | 163250-91-7 | 98.1% | 421.45 g/mol | C19H27N5O6 | 1 ML
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Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation and is supplied for research use only. It is available as a 10 mM solution in DMSO (1 mL) or as a solid in multiple milligram sizes.
- Orally active GPIIb/IIIa antagonist
- Inhibits platelet aggregation
- Available as 10 mM solution in DMSO (1 mL) and as solid in 5-100 mg sizes
- High purity (98.13%)
- Storage: solid at 4°C under nitrogen; in solvent at -80°C (up to 6 months) or -20°C (up to 1 month)
- Intended for research use only
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Indofine Chemical 7-AMINO-4-METHYLCOUMARIN, Flavonoid & Coumarins, 26093-31-2, 98+%, 250 mg
7-AMINO-4-METHYLCOUMARIN, Flavonoid & Coumarins, 26093-31-2, 98+%, 250 mg
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eMolecules 345633-76-3 | Ambeed | 44-Didodecyl-22-bithiophene | 1g | 490553312 | A315188 | MFCD24539449 | 502.9 | C32H54S2
ChemScene | (3-Bromo-5-ethoxyphenyl)boronic acid | 250mg | 569145745 | CS-0101385 | 849062-02-8 | MFCD07369739 | 244.880 | C8H10BBrO3
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