Sphingolipids
Abcam 3-Ketodihydrosphingosine hydrochloride, Ceramide biosynthesis intermediate, 10MG
MW 335.96 g/mol, Purity >98%. Necessary intermediate in ceramide (ab141745, ab141743) biosynthesis.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) | 74713-59-0 | 98.0% | 425.69 | 50 MG
C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. It possesses anti-proliferation properties and acts as a potent chemotherapeutic agent. It stimulates dendritic cells to promote T cell responses upon virus infections and induces slight activation of protein kinase (PKC) in vitro.
- Acts as a potent chemotherapeutic agent.
- Possesses anti-proliferation properties.
- Stimulates dendritic cells to promote T cell responses.
- Induces slight activation of protein kinase (PKC) in vitro.
- Irreversibly reduces tumor-cell proliferation.
- Can induce necrosis-like cell death.
- May increase endogenous ROS levels, causing anti-proliferation and triggering apoptosis.
- Increases CD8+ T cell response to influenza in mice.
Apexbio Technology LLC Ceramide(Synonyms: N-Acylsphingosine, Ceramides, Acylsphingosine, sphingosine N-acyl derivative, N-Acyl-D-sphingosine), 25mg, CAS: 3102-57-6.
Ceramide (CAS 3102-57-6) is a bioactive lipid molecule known to modulate diverse cellular processes including proliferation and differentiation It exerts its effects primarily by activating several serine/threonine protein phosphatases notably protein phosphatase-1 (PP1) protein phosphatase-2A (PP2A) and ceramide-activated protein phosphatase (CAPP) in vitro Due to its regulatory role in fundamental signaling pathways ceramide serves as a valuable research tool in investigations addressing cell cycle progression apoptosis and cellular homeostasis
Medchemexpress LLC N-(oleoyl)-ceramide | 5966-28-9 | MFCD01076442 | 99.9% | C36H69NO3 | 10MG
C18:1-ceramide is a naturally occurring ceramide subspecies used as a biochemical standard and research reagent in studies of lipid metabolism and metabolic disease, including type 2 diabetes. Supplied as solids and as a 10 mM solution in DMSO, it is intended for research use only.
- Ceramide subspecies involved in lipid signaling and metabolism.
- Used in studies of insulin resistance and type 2 diabetes.
- Available as solid quantities and as a ready-to-use DMSO solution.
- High purity (≈99.9%), suitable for analytical and biological assays.
- Molecular formula C36H69NO3; molecular weight 563.94 g/mol.
Avanti Polar Lipids Sphingomyelin (Egg, Chicken), Powder, 1 g
Sphingomyelin (Egg, Chicken), Powder, 1 g
Medchemexpress LLC DHA ceramide | 218608-43-6 | 98.7% | 609.96 | C40H67NO3 | 10 MG
DHA Ceramide (C22:6 Ceramide) is a high-purity ester-form ceramide supplied as a solid for biochemical and cell biology research. It is intended for in vitro use and is typically prepared in DMSO for cellular treatments. Store the dry material at -20°C protected from light and under nitrogen; reconstituted solutions have recommended cold storage lifetimes.
- High purity (98.65%) suitable for research applications.
- Available in small milligram-scale packages for flexible experimental use.
- Solid form soluble in DMSO at 100 mg/mL; ultrasonic treatment recommended.
- Provides molecular formula C40H67NO3 and molecular weight 609.96 g/mol for experimental planning.
- Recommended storage: store at -20°C protected from light and under nitrogen; solutions: -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Lyso-Tracker Red(Synonyms: LysoTracker Red DND-99, LysoTracker Red, LysoTracker Red fluorescent probe), 50ul, CAS: 231946-72-8.
Lyso-Tracker Red (CAS 231946-72-8) is a weakly basic fluorescent dye designed for labeling lysosomes in live cells. This cell-permeable molecule selectively accumulates within acidic lysosomal compartments due to protonation and subsequent entrapment in their low-pH environment. Unlike conventional lysosomal dyes such as neutral red and acridine orange, Lyso-Tracker Red displays superior organelle specificity, requiring nanomolar concentrations to clearly visualize lysosomes. Supplied as a 1 mM stock solution in DMSO, this probe is utilized for live-cell imaging studies investigating lysosomal function and trafficking pathways.
Cayman Chemical C162 S-hydroxy CeramIde 10mg
A synthetic ceramide; has no effect on C6 glioma cell viability at concentrations up to 20 µM
Apexbio Technology LLC Ceramide(Synonyms: N-Acylsphingosine, Ceramides, Acylsphingosine, sphingosine N-acyl derivative, N-Acyl-D-sphingosine), 5mg, CAS: 3102-57-6.
Ceramide (CAS 3102-57-6) is a bioactive lipid molecule known to modulate diverse cellular processes including proliferation and differentiation It exerts its effects primarily by activating several serine/threonine protein phosphatases notably protein phosphatase-1 (PP1) protein phosphatase-2A (PP2A) and ceramide-activated protein phosphatase (CAPP) in vitro Due to its regulatory role in fundamental signaling pathways ceramide serves as a valuable research tool in investigations addressing cell cycle progression apoptosis and cellular homeostasis
Cayman Chemical W-azIdo-C6 CeramIde 10mg
A clickable form of C6 ceramide; active against N. meningitidis and N. gonorrhoeae (MIC = 2 UG/ml for both); has been used to conjugate alkynylated fluorescent probes to liposomes containing ω-azido-C6 ceramide via a click reaction
Medchemexpress LLC C6 Ceramide | 124753-97-5 | 99.8% | 397.63 | 1 MG
C6 Ceramide | 124753-97-5 | 99.8% | 397.63 | 1 MG
Medchemexpress LLC Sphingomyelin (d18:1/12:0) | 474923-21-2 | 646.92 | C35H71N2O6P | 5mg
Sphingomyelin (d18 1/12 0) is a polar lipid with the activity of regulating cell signaling Sphingomyelin (d18 1/12 0) plays an important role in cell membranes affecting membrane fluidity and stability Sphingomyelin (d18 1/12 0) is also involved in lipid metabolism and has the potential to promote neuronal cell growth Sphingomyelin (d18 1/12 0) plays a key role in the function and development of the nervous system
Medchemexpress LLC N-Hexanoylsphingosine | 124753-97-5 | 99.8% | 397.63 | 100 MG
C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator exhibiting significant anticancer activity. It plays a role in mediating miR-29b expression, which is involved in suppressing the progression of multiple myeloma by targeting the Akt signal pathway. This compound demonstrates a range of anti-cancer properties and can enhance the effects of chemotherapy in drug-resistant cancer cells.
- Short-chain, cell-permeable ceramide pathway activator
- Possesses anticancer activity
- Mediates miR-29b expression
- Suppresses proliferation, migration, and angiogenesis of endothelial cells
- Targets the Akt signal pathway
- Induces cell cycle arrest and apoptosis
- Inhibits tumor growth
- Enhances chemotherapy effects in drug-resistant cancer cells
- Useful as an adjuvant for chemotherapeutic agents