Sphingolipids
Medchemexpress LLC C20 Ceramide (N-Arachidoyl-D-sphingosine) | 7344-02-7 | 99.1% | 594.01 | 25 MG
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a natural 20:0 ceramide and a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. C20 Ceramide acts as a key signal molecule mediating biological processes. It is for research use only and not sold to patients.
- Natural 20:0 ceramide
- N-acylsphingosine with eicosanoyl N-acyl group
- Acts as a key signal molecule
- Mediates cell growth, differentiation, senescence, and apoptosis
- For research use only
Avanti Polar Lipids C18:0-d7 GD3 Ceramide (d18:1/18:0-d7), synthetic, 100ug
GD3 ceramide is the main ganglioside within human breast milk. GD3 Ceramides are critical for apoptosis and present in high quantities in various tumor species. This GD2 Ceramide is the deuterated version, which will enable the easier study of structure, dynamics, and function of cell membranes.
Medchemexpress LLC N-hexanoylsphingosine | 124753-97-5 | 99.8% | 397.63 | C24H47NO3 | 10 MG
C6 ceramide is a short-chain, cell-permeable ceramide pathway activator used in cell-based research to induce apoptosis and modulate signaling pathways relevant to cancer progression and chemosensitivity.
- Induces apoptosis and cell cycle arrest in cancer cells.
- Enhances chemosensitivity in drug-resistant models.
- Soluble in DMSO at high concentrations for in vitro use.
- High purity for reproducible experimental results.
- Stable when stored as a powder at recommended temperatures.
- Available in multiple pack sizes for experimental flexibility.
Cayman Chemical C16 Ceramide d18 1 16 0
A sphingolipid; levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis; accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension; plasma levels are increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events; levels are increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer
Medchemexpress LLC 17:1 Lyso PC | 1246304-62-0 | C25H50NO7P | 25 MG
17:1 Lyso PC is a liposome designed to simulate biological phospholipid membranes. These liposomes, comprising concentric phospholipid bilayer membranes, are utilized in drug delivery systems for anti-cancer and anti-infection applications. It effectively encapsulates water-soluble payloads in its aqueous core and integrates lipophilic payloads into its lipid bilayer, proving particularly effective for antisense oligonucleotide delivery by overcoming issues like inefficient cellular uptake and rapid loss in the body.
- Simulates biological phospholipid membranes
- Forms concentric phospholipid bilayer vesicles
- Used in drug delivery systems for anti-cancer and anti-infection fields
- Encapsulates water-soluble payloads in aqueous core
- Integrates lipophilic payloads into lipid bilayer
- Addresses inefficient cellular uptake and rapid loss for antisense oligonucleotide delivery
Medchemexpress LLC C2 ceramide (ceramide 2) | 3102-57-6 | MFCD00153903 | 99.9% | 341.53 g/mol | C20H39NO3 | 10 MG
C2 ceramide (N-acetylsphingosine) is a short-chain ceramide used in biochemical and cell biology research as a lipid signaling molecule and protein phosphatase activator. It modulates cellular processes such as apoptosis, autophagy, and differentiation, and is applied in studies of mitochondrial function and epidermal barrier biology.
- Activates protein phosphatases PP1 and PP2A.
- Modulates apoptosis, autophagy, and cell differentiation.
- Cell-permeable short-chain ceramide for signaling studies.
- High reported purity for reproducible experiments.
- Applicable to mitochondrial function and skin barrier assays.