Steroids and derivatives
Apexbio Technology LLC Dexamethasone (DHAP) 50-02-2 5g
Dexamethasone (DHAP) is a synthetic glucocorticoid commonly utilized in biomedical research due to its potent anti-inflammatory function and immunomodulatory effects It exerts its mechanism through glucocorticoid receptor-mediated transcriptional modulation resulting in reduced transcriptional activity of NF- B signaling pathways in dendritic cells (DC) thus inhibiting DC maturation and activation This compound is frequently employed in experiments investigating immune regulation inflammation and cell differentiation processes including induction of differentiation in human mesenchymal stem cells (MSCs) Additionally dexamethasone is used in cancer cell biology research as it promotes autophagy in acute lymphoblastic leukemia-derived cell lines Reported IC50 values for dexamethasone-mediated inhibition of cellular inflammation responses typically range from 2 50 nM depending on specific cellular models and experimental conditions
Selleck Chemical LLC Medroxyprogesterone S3635-25mg
Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone It is a potent progesterone receptor agonist
Sigma Aldrich Fine Chemicals Biosciences Glycocholic acid hydrate synthetic, >=97% (HPLC) | 1192657-83-2 | MFCD06408004 | 5G
Glycocholic acid hydrate synthetic, >=97% (HPLC) | Purity: >=97% (HPLC) | 1192657-83-2 | MFCD06408004 | 5G
Apexbio Technology LLC Dexamethasone phosphate disodium 2392-39-4 500mg
Dexamethasone phosphate disodium (CAS 2392-39-4) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid-mediated signaling pathways thereby regulating immune and inflammatory responses Dexamethasone phosphate disodium exerts its biological activity primarily by binding to the glucocorticoid receptor initiating nuclear translocation and influencing gene transcription to suppress the expression and secretion of pro-inflammatory cytokines and chemokines Based on these pharmacological properties dexamethasone phosphate disodium holds research potential in studying inflammatory conditions immune response processes and associated signaling cascades in vitro and in vivo
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Sigma Aldrich Fine Chemicals Biosciences 2 Keto 3 methyl d3 butyrc500MG
2 Keto 3 methyl d3 butyrc500MG
![eMolecules Medchem Express / U-73343 / 5mg / 482203907 / HY-108630 / / 142878-12-4 / [null] / 466.666 / C29H42N2O3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448083.PNG-250.jpg)
eMolecules Medchem Express / U-73343 / 5mg / 482203907 / HY-108630 / / 142878-12-4 / [null] / 466.666 / C29H42N2O3
Medchem Express / U-73343 / 5mg / 482203907 / HY-108630 / / 142878-12-4 / [null] / 466.666 / C29H42N2O3
Medchemexpress LLC α-cholestane-d4 | 205529-74-4 | MFCD00216162 | 99.0% | C27H44D4 | 10MG
α-Cholestane-d4 is a deuterium-labeled analogue of α-cholestane used as a stable isotope internal standard and tracer in analytical workflows. It supports accurate quantitation, method development, and tracer studies in mass spectrometry and isotope-dilution assays, with high isotopic and chemical purity for reliable results.
- Deuterium-labeled internal standard for mass spectrometry
- High isotopic and chemical purity for accurate quantitation
- Suitable for isotope-dilution assays and tracer studies
- Available in small pack sizes for analytical use
- Molecular formula C27H44D4 and CAS 205529-74-4 for identification
Medchemexpress LLC 7-methylguanosine-d3 | 00-00-0 | 98.5% | 301.29 g·mol⁻¹ | C11H13D3N5O5 | 5 MG
7-Methylguanosine-d3 is a deuterium-labeled stable isotope of 7-methylguanosine intended as a high-purity reference standard for analytical and biochemical applications. It is supplied in small-mass packages suitable for use in quantitative mass spectrometry, tracer studies, and method development. The unlabeled parent compound has reported activity against cNIIIB nucleotidase (IC50 = 87.8 ± 7.5 μM).
- High-purity deuterium-labeled isotopic standard for accurate mass spectrometry.
- Suitable as an internal standard for LC-MS or GC-MS quantitation.
- Useful for tracer studies and metabolic labeling experiments.
- Provided in small mass vials compatible with analytical workflows.
- Molecular formula C11H13D3N5O5; molecular weight 301.29 g·mol⁻¹.
Selleck Chemical LLC Fluorometholone
Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye