Steroids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Dexamethasone | 50-02-2 | MFCD00064136 | 25mg
Dexamethasone | Purity: 98% | Mol Wt: 392.46 | 50-02-2 | MFCD00064136 | 25mg
Apexbio Technology LLC Dexamethasone (DHAP) 50-02-2 5g
Dexamethasone (DHAP) is a synthetic glucocorticoid commonly utilized in biomedical research due to its potent anti-inflammatory function and immunomodulatory effects It exerts its mechanism through glucocorticoid receptor-mediated transcriptional modulation resulting in reduced transcriptional activity of NF- B signaling pathways in dendritic cells (DC) thus inhibiting DC maturation and activation This compound is frequently employed in experiments investigating immune regulation inflammation and cell differentiation processes including induction of differentiation in human mesenchymal stem cells (MSCs) Additionally dexamethasone is used in cancer cell biology research as it promotes autophagy in acute lymphoblastic leukemia-derived cell lines Reported IC50 values for dexamethasone-mediated inhibition of cellular inflammation responses typically range from 2 50 nM depending on specific cellular models and experimental conditions
Medchemexpress LLC Hydrocortisone acepo 10mg | 74050-20-7 | 460.56 | C26H36O7 | 10 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) analytical standard supplied as a 10 mg package with 97% purity for research and analytical applications. It is used as a topical glucocorticoid reference standard in chromatographic and mass-spectrometric methods and in dermatoses research.
- Analytical reference standard for HPLC, GC, and MS methods.
- High purity (97%) suitable for quantitative and qualitative analysis.
- Supplied as a 10 mg package for small-scale laboratory use.
- Molecular formula C26H36O7 and molecular weight 460.56 g/mol for identification and calculations.
- Intended for research use only; not for human or veterinary administration.
Sigma Aldrich Fine Chemicals Biosciences Hydrocortisone Impurity D100MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Sigma Aldrich Fine Chemicals Biosciences Aldosterone | 52-39-1 | MFCD00051136 | 5 mg
Aldosterone | Purity: ≥95% | Mol Wt: 360.44 | 52-39-1 | MFCD00051136 | 5 mg
Sigma Aldrich Fine Chemicals Biosciences Cortisone >=98% | 53-06-5 | MFCD00003610 | 250MG
Cortisone >=98% | Purity: >=98% | Mol Wt: 360.44 | 53-06-5 | MFCD00003610 | 250MG
Apexbio Technology LLC Dexamethasone phosphate disodium 2392-39-4 100mg
Dexamethasone phosphate disodium (CAS 2392-39-4) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid-mediated signaling pathways thereby regulating immune and inflammatory responses Dexamethasone phosphate disodium exerts its biological activity primarily by binding to the glucocorticoid receptor initiating nuclear translocation and influencing gene transcription to suppress the expression and secretion of pro-inflammatory cytokines and chemokines Based on these pharmacological properties dexamethasone phosphate disodium holds research potential in studying inflammatory conditions immune response processes and associated signaling cascades in vitro and in vivo
Medchemexpress LLC Dexamethasone palmitate | 14899-36-6 | 99.7% | 10 MG
Dexamethasone palmitate (DXP) is a proagent of Dexamethasone and can be used for inflammation research. This compound has demonstrated significant biological activity both in vitro and in vivo.
- Affects cytokine concentration of RAW 264.7 cells in vitro.
- Shows in vitro anti-inflammatory effects by decreasing LPS-induced MCP-1 and TNF-α concentration in RAW 264.7 cells.
- Exhibits different distribution in ocular tissue at various times during in vivo studies.
- Affects VEGF-induced vascular hyperpermeability in vivo.
Medchemexpress LLC Hydrocortisone 17-butyrate | 13609-67-1 | 99.9% | 1 ML
Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid. It is used for psoriasis, eczema, and other inflammatory dermatoses. This compound has been shown to inhibit granuloma formation in rats and can induce vasoconstriction.
- Non-fluorinated topical corticosteroid
- Used for psoriasis, eczema, and other inflammatory dermatoses
- Inhibits granuloma formation in rats
- Can induce vasoconstriction
Apexbio Technology LLC Cortisone acetate 50-04-4 500mg
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Medchemexpress LLC Prednisone acetate-d3 | 125-10-0 | 96.5% | 403.48 | C23H25D3O6 | 10 MG
Prednisone acetate-d3 is the deuterium-labeled analog of prednisone 21-acetate used as a stable isotope internal standard for quantitative analysis by NMR, GC-MS, and LC-MS. It serves as a tracer in pharmacokinetic and metabolic studies and is supplied as a solid powder with storage recommendations for long-term stability.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS.
- Suitable tracer for pharmacokinetic and metabolic studies.
- High chemical purity (~96.5%) to support accurate quantitation.
- Solid powder form with recommended low-temperature storage for stability.
Sigma Aldrich Fine Chemicals Biosciences Aldosterone | 52-39-1 | MFCD00051136 | 25mg
Aldosterone | Purity: ≥95% | Mol Wt: 360.44 | 52-39-1 | MFCD00051136 | 25mg
Medchemexpress LLC Hydrocortisone acepo 5mg | 74050-20-7 | 460.56 g·mol⁻¹ | C26H36O7 | 5 MG
Hydrocortisone aceponate is supplied as an analytical standard of hydrocortisone 17-propionate 21-acetate for research and analytical applications, commonly used as a reference in assay development and dermatoses studies.
- Analytical standard of hydrocortisone aceponate for research and assays.
- Declared purity suitable for HPLC analysis (97%).
- Molecular formula C26H36O7 and molecular weight 460.56 g·mol⁻¹.
- Supplied in a small 5 mg quantity for analytical use.
- Suitable as a reference standard in topical glucocorticoid research.
Medchemexpress LLC Prednisone (Standard) | 53-03-2 | MFCD00003608 | 99.8% | 100 MG
Prednisone (Standard), also known as Dehydrocortisone (Standard), is an analytical standard of Prednisone. This corticosteroid agent exhibits anti-inflammatory and immunosuppressive effects and can be utilized to study diseases such as systemic lupus erythematosus. It is intended for research and analytical applications, commonly employed in qualitative, quantitative, and methodological experiments using techniques like HPLC, GC, and MS. Its molecular formula is C₂₁H₂₆O₅, with a molecular weight of 358.43, and it appears as a white to off-white solid.
- Analytical standard for research and analytical applications.
- High purity (99.81%) for reliable results.
- Useful in studying systemic lupus erythematosus.
- Supports various analytical methods like HPLC, GC, and MS.