Steroids and derivatives
Cambridge Isotope Laboratories 1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 100 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is a potent inhibitor of carbonic anhydrase (CA) with IC50 values of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It also has an anti-inflammatory effect and has potential for research into external ocular inflammation.
- Synthetic glucocorticoid corticosteroid
- Corticosteroid ester
- Potent inhibitor of carbonic anhydrase (CA)
- Anti-inflammatory effect
- Potential for external ocular inflammation research
- For research use only
Medchemexpress LLC Fluorometholone | 426-13-1 | 99.4% | 50 MG
Fluorometholone is a synthetic glucocorticoid and a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. It can be used for the research of dry eye. This product is for research use only and not sold to patients.
- Synthetic glucocorticoid
- Glucocorticoid receptor agonist
- Possesses anti-inflammatory and anti-allergic properties
- Can be used for the research of dry eye
- Increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in conjunctival and corneal epithelial cells through activation of glucocorticoid receptors
Selleck Chemical LLC Fluorometholone
Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye
Sigma Aldrich Fine Chemicals Biosciences Cortisone 21-Acetate | 50-04-4 | MFCD00003609 | 10g
Cortisone 21-Acetate | Purity: 99% | Mol Wt: 402.48 | 50-04-4 | MFCD00003609 | 10g
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 10 MG
(Z)-Guggulsterone is a constituent found in the Indian Ayurvedic medicinal plant Commiphora mukul. It functions by inhibiting the growth of human prostate cancer cells through apoptosis and hinders angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. It also acts as a potent FXR antagonist, reducing ACE2 expression and inhibiting SARS-CoV-2 infection. This product is intended for research use only and is not sold to patients.
- Inhibits growth of human prostate cancer cells through apoptosis
- Hinders angiogenesis by suppressing VEGF-VEGF-R2-Akt signaling
- Acts as a potent FXR antagonist
- Reduces ACE2 expression
- Inhibits SARS-CoV-2 infection
eMolecules 95975-55-6 | Medchem Express | Guggulsterone | 5mg | 482203886 | HY-107738 | MFCD01310757 | 312.453 | C21H28O2
Medchem Express | Guggulsterone | 5mg | 482203886 | HY-107738 | 95975-55-6 | MFCD01310757 | 312.453 | C21H28O2
Apexbio Technology LLC Estrone 53-16-7 10g
Estrone (53-16-7) is a naturally occurring estrogen that modulates estrogen receptor-mediated signaling pathways It is primarily synthesized in ovarian and adipose tissues and participates in the regulation of estrogen-dependent cellular and physiological processes Estrone exerts its biological activity primarily through binding and activating estrogen receptors Experimental model activity type and key metric (IC50/EC50) are not specified Based on these pharmacological properties estrone holds research potential in studies of estrogen receptor activation reproductive endocrinology menopausal hormone transitions and estrogen-dependent signaling pathways and diseases
Medchemexpress LLC Estrone (Standard) | 53-16-7 | 99.7% | 25 MG
Estrone (Standard) is the analytical standard of Estrone and is intended for research and analytical applications. Estrone (E1) is a natural estrogenic hormone, representing a main endogenous estrogen produced by various tissues, particularly adipose tissue. It is formed through the aromatization of androstenedione in fat cells.
- Used as an analytical standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Appearance: Solid
- Color: White to off-white
- Initial source: Microorganisms, endogenous metabolite
- Store under recommended conditions in the Certificate of Analysis
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
Sigma Aldrich Fine Chemicals Biosciences Estrone European Pharmacopoeia (EP) Reference Standard | 53-16-7 | MFCD00003620 |
Estrone European Pharmacopoeia (EP) Reference Standard | Mol Wt: 270.37 | 53-16-7 | MFCD00003620 |
Sigma Aldrich Fine Chemicals Biosciences Estrone >=99% | 53-16-7 | MFCD00003620 | 5G
Estrone >=99% | Purity: >=99% | Mol Wt: 270.37 | 53-16-7 | MFCD00003620 | 5G
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-(beta-D-glucuronide) sodium salt | 15087-01-1 | MFCD00271561 | 5MG
Estrone 3-(beta-D-glucuronide) sodium salt | Purity: >=99% (HPLC) | Mol Wt: 468.47 | 15087-01-1 | MFCD00271561 | 5MG