Steroids and derivatives
Medchemexpress LLC Prostaglandin D2 met 5mg | 49852-81-5 | 366.49 | C21H34O5 | 5 MG
Prostaglandin D2 methyl ester is a methyl-ester prodrug of prostaglandin D2 used in pharmacology and cell-based research to probe PGD2 receptor signaling. It is more lipid-soluble and cell-permeable than PGD2 and is applied to studies of DP and CRTH2 receptor pharmacology.
- Prodrug of prostaglandin D2 with increased lipid solubility and cell permeability.
- Suitable for receptor pharmacology and cell-based assays.
- Reported Ki values: mCRTH2 160 nM; mDP 175 nM; hCRTH2 460 nM; hDP 270 nM.
- Molecular formula C21H34O5; molecular weight 366.49.
- Purity 97.1%; appearance colorless to light yellow liquid.
- Packaged as a 5 mg vial (13.64 mM in 1 mL methyl acetate).
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 25 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It potently inhibits carbonic anhydrase (CA) and has anti-inflammatory effects, making it suitable for external ocular inflammation research.
- Potently inhibits carbonic anhydrase (CA)
- Inhibits hCA-I with IC50 of 2.18 μM
- Inhibits hCA-II with IC50 of 17.5 μM
- Used in inflammation/immunology research
- Appears as a white to off-white solid
TARGETMOL CHEMICALS INC Estrone sulfate potassium 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg and bulk. Please contact Fisher for quotes. Estrone sulfate potassium is an estrogen ester and conjugate, a natural endogenous steroid. Purity 99.05%
Medchemexpress LLC Estrone 3-methyl ether | 1624-62-0 | MFCD00046228 | 97.4% | 284.39 g/mol | C19H24O2 | 10 MG
Estrone 3-methyl ether is a synthetic steroid intermediate used in organic synthesis and research on estrogen receptor modulators. It is supplied as a solid with high purity and is used as a building block in medicinal chemistry and assay development.
- CAS number: 1624-62-0.
- Molecular formula: C19H24O2.
- Molecular weight: 284.39 g/mol.
- Purity: 97.4%.
- Physical form: solid.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (6 months) or -20°C (1 month).
- Common applications: synthesis of estrogen receptor modulators and medicinal chemistry building block.
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | MFCD00056410 | 99.5% | 388.52 | C18H21KO5S | 5 MG
Estrone sulfate potassium is the potassium salt of estrone sulfate, an endogenous estrogen conjugate supplied for laboratory research. It is available as a high-purity solid and as a DMSO solution for in vitro studies, and is intended for research use only.
- High purity 99.45%.
- Molecular weight 388.52 and formula C18H21KO5S.
- Available in multiple sizes, including 5 mg, and as a 10 mM solution in DMSO.
- Soluble in DMSO for preparation of stock solutions.
- Supplied for research use only; not for human or clinical use.
- May be restricted or controlled in some territories.
Apexbio Technology LLC Estrone 53-16-7 5g
Estrone (53-16-7) is a naturally occurring estrogen that modulates estrogen receptor-mediated signaling pathways It is primarily synthesized in ovarian and adipose tissues and participates in the regulation of estrogen-dependent cellular and physiological processes Estrone exerts its biological activity primarily through binding and activating estrogen receptors Experimental model activity type and key metric (IC50/EC50) are not specified Based on these pharmacological properties estrone holds research potential in studies of estrogen receptor activation reproductive endocrinology menopausal hormone transitions and estrogen-dependent signaling pathways and diseases
Medchemexpress LLC Estradiol (Standard) | 50-28-2 | MFCD00003693 | 99.98% | 100 MG
Estradiol (Standard) is the analytical standard of Estradiol, a steroid hormone and the major female sex hormone. This compound can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. It is used in research for cancers, neurodegenerative diseases, and neural tissue engineering.
- Used as a reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Promotes neural differentiation of human endometrial stem cells
- Supports research in cancers, neurodegenerative diseases, and neural tissue engineering
- Commonly used in HPLC, GC, and MS applications
Medchemexpress LLC Estradiol dipropionate | 113-38-2 | 99.5% | 25 MG
Estradiol dipropionate is a combined estrogen-progesterone, functioning as an estrogen and progesterone agonist. It is intended for research use only.
- Acts as an estrogen and progesterone agonist.
- Used in research for studying uterine response to estradiol under the action of chorionic gonadotropin in mice.
Innovative Reseach Of America INNOVATIVE RESEARCH OF AMERICA
NC3903867 0.36 MG 17B ESTRADIOL PELLETS
Apexbio Technology LLC Cortisone acetate 50-04-4 10mM (in 1mL DMSO)
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Medchemexpress LLC Hydrocortisone phosphate sodium | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g·mol⁻¹ | C21H29Na2O8P | 50 MG
Hydrocortisone phosphate sodium is the disodium phosphate salt of hydrocortisone, a water-soluble corticosteroid used as a research reagent. It has corticosteroid activity with relatively low anti-inflammatory potency and a short duration of action, and is used in biochemical and pharmacological studies, including research on ocular conditions and gastric ulcers.
- Water-soluble sodium phosphate salt suitable for aqueous formulations.
- Useful for biochemical and pharmacological research of corticosteroid activity.
- Relatively low anti-inflammatory potency with short duration of action.
- High purity and defined molecular weight for reproducible results.
- Stable when stored sealed and away from moisture; follow cold storage recommendations for solutions.
Medchemexpress LLC Cortisone acetate | 50-04-4 | 99.9% | 402.48 | 25 G
Cortisone acetate, also known as Cortisone 21-acetate, is an oxidized metabolite of Cortisol, which is a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, cortisone acetate can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Functions as an immunosuppressant.
- Acts as an anti-inflammatory agent.
- Is an oxidized metabolite of cortisol.
- Can partially intervene in binding of glucocorticoid to glucocorticoid-receptor at high concentrations.