Purine nucleosides
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | 99.9% | 250.26 g/mol | C11H14N4O3 | 1 ML
7-deaza-2'-deoxyadenosine is a deoxynucleoside used as a biochemical reagent and building block for synthesis and oligonucleotide research.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as 1 mL vial.
- High purity, reported as 99.9%.
- Molecular weight 250.26 g/mol.
- Molecular formula C11H14N4O3.
- CAS number 60129-59-1 for unambiguous identification.
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 5 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound shows moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of Guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms and purine metabolism.
- For research use only.
Medchemexpress LLC Deoxyguanosine triphosphate trisodium | 93919-41-6 | 573.13 | 1 ML
Deoxyguanosine triphosphate (dGTP) trisodium, 100 mM Solution, PCR Grade is a raw material used by DNA polymerase to synthesize long DNA chains during DNA replication. It is also used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided as an aqueous solution.
- Used by DNA polymerase to synthesize long DNA chains during DNA replication.
- Used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification.
- Provided in the form of aqueous solution.
Medchemexpress LLC Adenosine, 5'-deoxy- | 4754-39-6 | 99.9% | 251.246 | 25 MG
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. It shows anti-orthopoxvirus activity.
- Oxidized nucleoside.
- Shows anti-orthopoxvirus activity.
Medchemexpress LLC 3'-deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 1 ML
3'-deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 1 ML
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 50 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death for the majority of cancer cell lines tested with IC50s between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreases tumor growth rate and increases telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Results in rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | MFCD00672266 | >97.0% | 250.25 g/mol | C11H14N4O3 | 100 MG
7-deaza-2'-deoxyadenosine is a deoxynucleoside analog used as a biochemical reagent for research applications. It is used in studies of nucleic acid structure and function, and has been reported to inhibit DNA synthesis and related polymerase reactions.
- Oligodeoxynucleotide analog for biochemical research.
- Reported inhibitor of DNA synthesis and polymerase activity.
- Molecular formula: C11H14N4O3.
- Molecular weight: 250.25 g/mol.
- CAS number: 60129-59-1.
- Typical purity reported around 98%, minimum 97%.
- Available as a 100 mg quantity.
- For research use only; not for diagnostic or therapeutic use.
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | 99.2% | 331.22 | C10H14N5O6P | 25 MG
2'-Deoxyadenosine-5'-monophosphate (dAMP) is a deoxyribonucleotide used as an analytical standard and reference material for nucleic acid research, method validation, and chromatographic or mass-spectrometry assays. Supplied as a solid in amber glass packaging, it is intended for calibration, quantitation, and analytical method development.
- High purity analytical standard suitable for HPLC and MS.
- Purity confirmed by HPLC (99.15% reported by COA).
- Molecular formula C10H14N5O6P and molecular weight 331.22.
- Supplied in brown glass to protect from light and moisture.
- Intended for calibration, method validation, and quantitative analyses.
Alkali Scientific 2' Deoxyguanosine monohydrate, 5 Grams
2'-Deoxyguanosine Monohydrate is a nucleoside involved in DNA replication and repair processes. It is a critical component of nucleic acids, particularly in the synthesis of the DNA molecule where it pairs with cytosine. This reagent is commonly used in molecular biology and biochemistry applications, including DNA synthesis, sequencing, and polymerase chain reactions (PCR). The 5-gram quantity is ideal for labs performing high-throughput DNA synthesis, sequencing, and various genetic studies. It is an essential component for laboratories working with nucleic acids, particularly in the synthesis of oligonucleotides and the study of nucleotide incorporation into DNA sequences.
