Purine nucleosides
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 25 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound demonstrates moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms.
- Useful for studying purine metabolism.
- Displaces 50 nM [3H]-guanosine binding to rat brain membranes.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
Cayman Chemical 2-DeoxyadenosIn-5-monphos 1g
A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage
Medchemexpress LLC Deoxyguanosine triphosphate trisodium | 93919-41-6 | 573.13 | 5 ML
Deoxyguanosine triphosphate (dGTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication. It is also used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided in the form of aqueous solution.
- Provided in the form of aqueous solution.
- Used by DNA polymerase to synthesize long DNA chains during DNA replication.
- Used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification.
Medchemexpress LLC N6-Threonylcarbamoyladenosine | 24719-82-2 | 99.6% | 412.35 | 1 MG
N6-Threonylcarbamoyladenosine is a common nucleoside that can decorate and become tRNA. It is for research use only.
- Purity of 99.62%
- Molecular weight of 412.35
- Chemical formula: C15H20N6O8
- Appearance: Solid
- Color: Off-white to light brown
- Storage conditions: -20°C for powder, -80°C for 6 months in solvent
Medchemexpress LLC 2'-Deoxyguanosine-d13 | 961-07-9 | 99.9% | 280.32 | 5 MG
2'-Deoxyguanosine-d13 is a deuterium-labeled version of 2'-Deoxyguanosine. It is intended for research use only and can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
Medchemexpress LLC N6-cyclopentyladenosine | 41552-82-3 | MFCD00036845 | 100.0% | 335.36 g/mol | C15H21N5O4 | 1 ML
N6-Cyclopentyladenosine is a selective adenosine A1 receptor agonist used as a research reagent in pharmacology and receptor signaling studies. Supplied as a 10 mM solution in a 1 mL vial, it is intended for in vitro experiments and receptor-binding assays.
- Selective adenosine A1 receptor agonist for pharmacological studies.
- Provided as a 10 mM solution for ready-to-use experiments.
- High chemical purity suitable for research applications.
- Compact 1 mL vial format for small-scale assays.
- Molecular weight 335.36 g/mol; molecular formula C15H21N5O4.
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
Medchemexpress LLC Adenosine, 5'-deoxy- | 4754-39-6 | 99.9% | 251.246 | 50 MG
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. It shows anti-orthopoxvirus activity.
- Oxidized nucleoside
- Found in the urine of normal subjects
- Shows anti-orthopoxvirus activity
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Selleck Chemical LLC 2 3 -Dideoxyadenosine
2 3 -Dideoxyadenosine (ddA ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication
Medchemexpress LLC 6-Thio-2'-deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This compound has shown rapid cell death in various cancer cell lines with IC50 values between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreased tumor growth rate, outperforming 6-thioguanine treatment, and increased telomere dysfunction in tumor cells in vivo. It is for research use only.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in various cancer cell lines
- Decreases tumor growth rate in mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo