Purine nucleotides
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 25mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 10mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5 betagama imi100MG
Guanosine 5prime-[beta gamma-imido]triphosphate (GMP-PNP Gpp(NH)p) is a non-hydrolyzable analog of GTP that binds and irreversibly activates G proteins. Gpp(NH)p is used in a variety of applications that involve GTP binding including GTP-activation GTP-inhibition GTP transport GTP hydrolysis and GTP structure stabilization. Since a cycle of GTP binding hydrolysis and release is required for the initiation of protein translocation across the endoplasmic reticulum guanosine 5prime-[beta gamma-imido]triphosphate is often used in studies of protein synthesis. Gpp(NH)p is used to activate ADP-ribosylation factors and to modulate G proteins involved in cell signaling protein synthesis and other metabolic processes.
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 100 MG
Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
- Activator of signal transducing G proteins
- Energy-rich precursor in DNA and RNA biosynthesis
- For research use only
Medchemexpress LLC 8-azidoadenosine 5'-triphosphate trisodium | 00-00-0 | 98.1% | 614.14 | C10H12N8Na3O13P3 | 5 MG
8-Azido-ATP trisodium is a photoreactive adenosine triphosphate analog supplied as the trisodium salt in solution. It is used to photo-crosslink and label ATP-binding proteins and serves as an azide-containing reagent for click chemistry and protein-nucleotide interaction studies.
- Photoreactive ATP analog for photo-crosslinking and protein identification.
- Azide functionality enables copper-catalyzed and strain-promoted click chemistry.
- Supplied as trisodium salt in a solution form suitable for direct use or dilution.
- High reported purity, supporting reproducible experimental results.
- Storage guidelines support frozen stock solutions for long-term stability.
Medchemexpress LLC 8-azidoadenosine 5'-triphosphate trisodium | 00-00-0 | 98.1% | C10H12N8Na3O13P3 | 10MG
8-Azido-ATP trisodium is a photoreactive adenosine triphosphate analog used for photoaffinity labeling and identification of ATP-binding proteins and nucleotide-interacting enzymes. Supplied as the trisodium salt with high purity (98.1%), it is intended for research applications involving UV-activated crosslinking to probe protein-nucleotide interactions.
- Photoreactive azido group enables UV-activated crosslinking to binding partners.
- Suitable for identifying ATP-binding proteins and nucleotide-interacting enzymes.
- Available as the water-soluble trisodium salt for aqueous assays.
- High purity suitable for analytical and biological experiments.
- Compatible with downstream identification techniques such as SDS-PAGE and mass spectrometry.
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 200 MG
Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. The chemical formula is C10H13N5Na3O14P3·xH2O and it appears as a white to off-white solid.
- Activator of signal transducing G proteins
- Energy-rich precursor of mononucleotide units
- Involved in enzymatic biosynthesis of DNA and RNA
- Appears as a white to off-white solid
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 50ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 10ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 100ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 50 MG
Guanosine 5'-triphosphate trisodium salt hydrate (5'-GTP trisodium salt hydrate) is a chemical reagent that functions as an activator for signal transducing G proteins. It also serves as an energy-rich precursor of mononucleotide units, which are essential for the enzymatic biosynthesis of DNA and RNA. This product is intended for research use only.
- Functions as an activator for signal transducing G proteins.
- Serves as an energy-rich precursor of mononucleotide units.
- Essential for the enzymatic biosynthesis of DNA and RNA.
- Intended for research use only.
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | MFCD29924712 | >98.0% | 945.85 g/mol | C32H58N11O14P3S | 10 MG
ATP-polyamine-biotin is a cell-permeable ATP analogue used as an efficient kinase co-substrate to transfer a biotin tag to kinase substrates in vitro and in live cells. It facilitates detection and enrichment of phosphorylated proteins for downstream analysis in biochemical and cell-based assays.
- Promotes biotin labeling of kinase substrates in live cells.
- Functions as an efficient ATP cosubstrate for kinases.
- Enables detection and enrichment of phosphorylated proteins.
- Provided with high purity suitable for biochemical assays.
- Available in multiple pack sizes, including 10 mg.
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 500 MG
Guanosine 5'-triphosphate trisodium salt hydrate activates signal transducing G proteins and functions as an energy-rich precursor for mononucleotide units in the enzymatic biosynthesis of DNA and RNA. This product is intended for research use only.
- Activates signal transducing G proteins
- Precursor for DNA and RNA biosynthesis
- Solid, white to off-white physical form
- Store at -20°C under nitrogen, away from moisture
- When in solvent, stable at -80°C for 6 months and -20°C for 1 month
- Soluble in H2O at ≥ 150 mg/mL
Medchemexpress LLC Adenosine | 58-61-7 | 99.96% | 100 G
Adenosine is an endogenous autacoid that acts through four G protein-coupled receptors (A1, A2A, A2B, and A3). It influences various cellular physiological processes. For research use only.
- Acts on A1, A2A, A2B, and A3 G protein-coupled receptors
- Influences neuronal activity, vascular function, platelet aggregation, and blood cell regulation
- Generated from ATP and AMP
- Antagonized by xanthines (e.g., caffeine)
- Exhibits cytotoxic effects at high concentrations
- Induces apoptosis and autophagy in cancer cells
- Inhibits cell viability and triggers ER stress
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 97.1% | C16H14N6S | 10MG
Adenosine receptor antagonist 3 is a small-molecule research compound that antagonizes adenosine receptors and is used in in vitro pharmacology and GPCR/G protein signaling studies. Supplied as a light-yellow solid and as a 10 mM solution in DMSO, it has a reported purity of 97.1% and molecular formula C16H14N6S.