Pyrimidine nucleosides
Cayman Chemical 2-DeoxycytIdIn 1g
A deoxyribonucleoside; phosphorylated by deoxycytidine kinase in the cytosol or TK2 in mitochondria to form dCMP; oral administration in combination with deoxythymidine delays disease onset and increases lifespan in a mouse model of TK2 deficiency
Apexbio Technology LLC 2-Deoxyuridine 5-monophosphate disodium 42155-08-8 250mg
2-Deoxyuridine 5-monophosphate disodium (CAS 42155-08-8) is a nucleotide analog recognized as a natural substrate for thymidylate synthase (TS) TS catalyzes the methylation of this compound utilizing 5 10-methylenetetrahydrofolate as a methyl donor to generate deoxythymidine 5-monophosphate (dTMP) This enzymatic conversion constitutes an essential step in the de novo synthesis of thymidine nucleotides required for DNA replication 2-Deoxyuridine 5-monophosphate disodium is widely employed in studies exploring DNA synthesis the thymidylate biosynthetic pathway and the regulation of nucleotide metabolism
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.9% | 50 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Synonyms: Deoxycytidine, Cytosine deoxyriboside, Deoxyribose cytidine
- Molecular weight: 227.22
- Formula: C9H13N3O4
- Appearance: Solid
- Color: White to off-white
- Storage conditions: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Medchemexpress LLC Cytidine, 2'-deoxy-5-(hydroxymethyl) | 7226-77-9 | 100.0% | C10H15N3O5 | 10MG
5-Hydroxymethyl-2'-deoxycytidine (5hmdC) is a nucleoside analog used as a reference reagent in epigenetic and DNA modification research. It is commonly used to study DNA methylation and demethylation pathways and for analytical method development and quantification assays.
- Used as a reference standard for DNA methylation and demethylation studies.
- High purity confirmed by HPLC (99.96%).
- Available in solid and solution formats, including DMSO solutions for immediate use.
- Suitable for analytical method development and quantification assays.
- Supplied with a certificate of analysis providing batch-specific quality data.
Chem-Impex International, Inc. 2'-Deoxycytidine | 951-77-9 | MFCD00006547 | 5G
2'-Deoxycytidine, 951-77-9, MFCD00006547, 5G
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 25 MG
3′-Deoxyuridine is a potential anticancer and antiviral agent that inhibits bovine diarrhoea virus (BVDV) production. It is for research use only and appears as a white to light yellow solid.
- Potential anticancer agent
- Potential antiviral agent
- Inhibits bovine diarrhoea virus (BVDV) production
- For research use only
- Appearance: Solid
- Color: White to light yellow
Medchemexpress LLC 2'-deoxyuridine | 951-78-0 | MFCD00006527 | 99.2% | 228.20 g/mol | C9H12N2O5 | 10 MG
2'-Deoxyuridine standard supplied as an analytical reference for research and analytical applications. It serves as a reference compound for biochemical assays, method development, and studies of nucleotide metabolism and neurodegenerative disease models.
- Suitable as an analytical reference standard for biochemical and pharmaceutical assays.
- High purity, 99.2%.
- Consistent chemical identity: C9H12N2O5, MW 228.20 g/mol.
- Available in small quantities for analytical use, including 10 mg vials.
- Shipped at room temperature in continental US; store per certificate of analysis.
Medchemexpress LLC 2'-Deoxyuridine (Standard) | 951-78-0 | 99.2% | 25 MG
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine, intended for research and analytical applications. It is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Used as an analytical standard.
- Precursor in the synthesis of Edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
- Promising for Alzheimer's disease research.
- Utilized in HPLC, GC, and MS research experiments.
Sigma Aldrich Fine Chemicals Biosciences 3'-Azido-3'-deoxythymidine >=98% (HPLC) | 30516-87-1 | MFCD00006536 | 1G
3'-Azido-3'-deoxythymidine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 267.24 | 30516-87-1 | MFCD00006536 | 1G
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 50 MG
4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Functions as a purine nucleoside analogue.
- Demonstrates broad antitumor activity.
- Targets indolent lymphoid malignancies.
- Inhibits DNA synthesis.
- Induces apoptosis.
Cambridge Isotope Laboratories 2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 50 UMOL
2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 50 UMOL
Cambridge Isotope Laboratories 2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 25 UMOL
2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 25 UMOL
Selleck Chemical LLC 5-Methyl-2 -deoxycytidine
5-Methyl-2 -deoxycytidine (5-Me-dC 5-Methyldeoxycytidine 5MedCyd) is a minor component found in most eukaryotic DNA