Pyrimidine nucleotides
Medchemexpress LLC Propanoic acid, 2,3-bis(phosphonooxy)-, pentasodium salt | 102783-53-9 | MFCD00070074 | 95.0% | C3H3Na5O10P2 | 10MG
2,3-Diphospho-D-glyceric acid pentasodium salt is the pentasodium salt of the endogenous metabolite 2,3-diphospho-D-glyceric acid supplied as a solid for research use. It functions as a selective inhibitor of vascular calcification and is reported with CAS 102783-53-9, molecular formula C3H3Na5O10P2, and a typical purity of 95.0%.
- Endogenous metabolite with inhibitory activity against vascular calcification.
- White to light yellow solid, soluble in water for aqueous preparations.
- Supplied with reported purity 95.0% suitable for research applications.
- Defined molecular formula C3H3Na5O10P2 and molecular weight 375.95 g/mol.
- Provided with supporting documentation such as a datasheet and certificate of analysis.
Medchemexpress LLC 2,3-diphospho-D-glyceric acid pentasodium salt | 102783-53-9 | MFCD00070074 | 95.0% | 375.95 g/mol | C3H3Na5O10P2 | 5 MG
2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus biochemical reagent (CAS 102783-53-9) used in research to study red blood cell physiology and metabolic pathways. It binds hemoglobin and reduces its oxygen affinity, and is employed in biochemical and cellular assays.
Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), sodium salt (1:x) | 21931-53-3 | 98.0% | 25 G
Uridine 5'-diphosphate sodium salt is an endogenous metabolite that acts as a potent and selective native agonist for the P2Y6 receptor (EC50=300 nM) and a potent antagonist for the P2Y14 receptor. It catalyzes the glucuronidation of various substrates and is crucial for nucleic acid (RNA) biosynthesis. For research use only.
- Potent and selective P2Y6 receptor agonist
- Potent P2Y14 receptor antagonist
- Catalyzes glucuronidation of various substrates
- Used in nucleic acid (RNA) biosynthesis
- Induces microglial CCL2 and CCL3 mRNA expression
- Activates NFATc1 and NFATc2 in microglia
Medchemexpress LLC Uridine 5'-diphosphate (sodium salt) | 21931-53-3 | 98.0% | 10 G
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). It is an endogenous metabolite that catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.
- Potent, selective P2Y6 receptor native agonist.
- Potent P2Y14 antagonist.
- Endogenous metabolite.
- Catalyzes glucuronidation of various substrates.
- Used in nucleic acid (RNA) biosynthesis.
- Induces microglial CCL2 and CCL3 mRNA expression.
- Induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor.
- Induces activation of NFATc1 and NFATc2 in microglia.
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 50mg, CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 10mM (in 1mL H2O), CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
![Alkali Scientific N Acetyl D glucosamine [2 Acetamido 2 deoxy D glucopyranose GlcNAc], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661269.jpg-250.jpg)
Alkali Scientific N Acetyl D glucosamine [2 Acetamido 2 deoxy D glucopyranose GlcNAc], 5 G
N-Acetyl D Glucosamine is an amino sugar and carbohydrate derivative used in various biochemical and molecular biology applications. It is widely utilized in research related to glycosaminoglycans and proteoglycans, which are essential components of extracellular matrices. The 5g format of this reagent is suitable for studies in cell biology, molecular research, and biochemical analysis. N-Acetyl D Glucosamine is often used in the preparation of cell culture media, as a substrate for enzyme assays, and in the study of metabolic pathways involving glycosylation. It is also relevant in the research of cartilage and joint health, as it is a building block of hyaluronic acid.
Medchemexpress LLC Uridine 5'-monophosphate | 58-97-9 | 99.8% | 324.18 g/mol | C9H13N2O9P | 100 MG
Uridine 5'-monophosphate (free acid) is an analytical standard used as a reference compound in biochemical assays, chromatography, and mass spectrometry. It is applied in studies of nucleotide metabolism and as a calibration standard in analytical workflows. The material is supplied as a high-purity solid suitable for research applications.
- Purity 99.8%.
- Molecular weight 324.18 g/mol.
- Molecular formula C9H13N2O9P.
- Appearance solid, white to off-white.
- Pack size 100 MG.
- Storage follow recommended conditions in the certificate of analysis.
Medchemexpress LLC Uridine 5'-monophosphate-13C9,15N2 disodium | 58-97-9 | 99.8% | 379.07 | 1 MG
Uridine 5'-monophosphate-13C9,15N2 disodium is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt. Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Uridine | 26287-69-4 | 244.20 | 250 MG
L-Uridine is an enantiomer of the normal RNA constituent D-uridine. It can be isolated from the Polyporaceae fungus *Poria cocos* (Schw.) and acts as a phosphate acceptor for nucleoside phosphotransferases. In vitro, L-uridine (7 min) is converted to 5'-L-uridylic acid, with a Km value of 28 mM.
- Enantiomer of D-uridine
- Isolated from *Poria cocos* (Schw.)
- Acts as a phosphate acceptor for nucleoside phosphotransferases
- High purity (99.81%)
- Available as a solid
- Soluble in various in vitro dissolution methods
- Stable under specified storage conditions
Medchemexpress LLC Uridine 5'-monophosphate disodium salt | 3387-36-8 | 99.9% | 368.14 | 5 G
Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. It can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
- Promotes late apoptosis in pig intestinal epithelial cells IPEC-J2.
- Promotes apoptosis and renewal of intestinal villus tip epithelial cells in pigs.
- Benefits gut development and and reduces diarrhea.
- Enhances the synthesis of CDP-choline in the brains of gerbils.
- Has protective properties for the heart in rats, preventing ischemic injury and some arrhythmias.
Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), sodium salt (1:x) | 21931-53-3 | 98.0% | 250 MG
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y6 receptor native agonist and a potent P2Y14 antagonist. It is an endogenous metabolite involved in nucleic acid (RNA) biosynthesis and catalyzes the glucuronidation of various substrates. This product is for research use only.
- Potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52)
- Potent P2Y14 antagonist (pEC50=7.28)
- Induces microglial CCL2 and CCL3 mRNA expression
- Induces chemokine expression in microglia
- Activates NFATc1 and NFATc2 in microglia
- White to off-white solid appearance
- Store at -20°C under nitrogen