Pyrimidine nucleotides
Medchemexpress LLC D-(+)-glucosamine hydrochloride | 66-84-2 | 215.63 | 50 MG
Glucosamine hydrochloride is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, also used as a dietary supplement. It is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, exerting pharmacological effects on osteoarthritic cartilage and chondrocytes. This product exhibits dose-dependent DPPH antioxidant activity and inhibits HIF-1α at the protein level.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
Medchemexpress LLC Glucosamine (sulfate) | 29031-19-4 | 277.25 | 100 MG
Glucosamine sulfate is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which, when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level with short-term treatment.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
![Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester, sodium salt (1:2) | 91183-98-1 | 99.92% | 651.32 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000440056-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester, sodium salt (1:2) | 91183-98-1 | 99.92% | 651.32 | 25 MG
UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT). OGT is a nucleocytoplasmic glycosyltransferase that modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within the cytosol and nucleus.
- Donor substrate of O-GlcNAc transferase (OGT).
- Modifies thousands of proteins by adding a unique N-acetylglucosamine residue.
- For research use only.
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | 215.63 | 10 G
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans found in the cartilage matrix and synovial fluid. When administered exogenously, it exhibits pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Purity: 98.0%
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level, and decreases phosphorylation of p70S6K and S6, which are translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Appearance: White to off-white solid.
Medchemexpress LLC UDP-glucosamine (disodium) | 1355005-51-4 | 99.4% | 609.28 | 1 MG
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which facilitates the attachment of O-GlcNAc to proteins. O-GlcNAcase is responsible for removing O-GlcNAc from proteins. This compound is the final product of the hexosamine biosynthesis pathway, primarily controlled by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT).
- Substrate for O-GlcNAc transferase
- End product of the hexosamine biosynthesis pathway
Medchemexpress LLC Glucosamine (hydrochloride) | 66-84-2 | 215.63 | 1 G
Glucosamine hydrochloride is an amino sugar and a precursor in the biochemical synthesis of glycosylated proteins and lipids. It is used as a dietary supplement and is a natural constituent of glycosaminoglycans in cartilage matrix and synovial fluid. When administered exogenously, it exerts pharmacological effects on osteoarthritic cartilage and chondrocytes. This product is for research use only.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level during short-term treatment.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys.
- Appearance: white to off-white solid.
- Purity: 98.0%.
Medchemexpress LLC D-Glucosamine (sulfate) | 29031-19-4 | 277.25 | 500 MG
Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is used as a dietary supplement and is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which, when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Used as a dietary supplement.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level, decreasing phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Purity of 98.0%.
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | 215.63 | 5 G
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, and when administered exogenously, it exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity
- Inhibits HIF-1α at the protein level and decreases phosphorylation of p70S6K and S6
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin
Medchemexpress LLC UDP-GlcNAz disodium | 1611490-64-2 | 99.7% | C17H24N6Na2O17P2 | 100 MG
UDP-GlcNAz disodium is an analogue of UDP-GlcNAc disodium. It functions as a donor substrate for various N-acetylgalactosaminyltransferases and is a click chemistry reagent with an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Functions as a sugar donor
- Serves as a substrate for OGTase and O-GlcNAcase
- Capable of glycosylating p62
- Glycosidic bond can be cleaved by O-GlcNAcase catalysis
- Useful in research concerning protein glycosylation
- Can be incorporated into nuclear proteins in Jurkat cells
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | 215.63 | 100 G
Glucosamine hydrochloride, also known as D-Glucosamine hydrochloride, is an amino sugar used as a dietary supplement and is a key precursor in the biochemical synthesis of glycosylated proteins and lipids. It is a natural component of glycosaminoglycans found in cartilage matrix and synovial fluid. When administered exogenously, it demonstrates pharmacological effects on osteoarthritic cartilage and chondrocytes.
- It acts as an amino sugar.
- It serves as a precursor in the biochemical synthesis of glycosylated proteins and lipids.
- It is a natural constituent of glycosaminoglycans in cartilage matrix and synovial fluid.
- It exhibits pharmacological effects on osteoarthritic cartilage and chondrocytes.
- It demonstrates dose-dependent DPPH antioxidant activity.
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | MFCD00135831 | 215.63 | 1 ML
Glucosamine hydrochloride is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, often used as a dietary supplement. It is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, exerting pharmacological effects on osteoarthritic cartilage and chondrocytes when administered exogenously.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level and decreases phosphorylation of p70S6K and S6 during short-term treatment.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Targets human endogenous metabolite and microbial metabolite.
Medchemexpress LLC Glucosamine (D-Glucosamine; Chitosamine) | 3416-24-8 | MFCD01631140 | ≥98.0% | 25 MG
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, and when administered exogenously, it exerts pharmacological effects on osteoarthritic cartilage and chondrocytes. It is for research use only and not sold to patients.
- Amino sugar and precursor in biochemical synthesis.
- Natural constituent of glycosaminoglycans.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at protein level.
- Decreases phosphorylation of p70S6K and S6.
- Decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin.
Medchemexpress LLC UDP-glucosamine (UDP-GlcNAc) disodium | 1355005-51-4 | 99.4% | C15H23N3Na2O16P2 | 10MG
UDP-glucosamine disodium is the disodium salt of uridine diphosphate glucosamine (UDP-GlcNAc), a nucleotide sugar substrate used by O-GlcNAc transferase for protein O-GlcNAcylation. It is supplied as a white to off-white solid with high reported purity and strong aqueous solubility, intended for biochemical and enzymatic assays.
- High purity (99.4%) suitable for biochemical assays.
- White to off-white solid for convenient handling and storage.
- Soluble in water (250 mg/mL; ultrasonic may be required) for assay preparation.
- Stable when stored sealed and kept away from moisture; solution stability recommended at low temperatures.
- Functionally active as a substrate for O-GlcNAc transferase in protein modification studies.
- Molecular weight 609.28 g/mol and molecular formula C15H23N3Na2O16P2.
Medchemexpress LLC D-glucosamine 6-phosphate sodium | 70442-23-8 | MFCD00069826 | 99.9% | 281.13 g/mol | C6H13NNaO8P | 5mg
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research Glycobiology studies the structure synthesis biology and evolution of sugars It involves carbohydrate chemistry enzymology of glycan formation and degradation protein-glycan recognition and the role of glycans in biological systems This field is closely related to basic research biomedicine and biotechnology[1]
Medchemexpress LLC D-glucosamine 6-phosphate sodium | 70442-23-8 | MFCD00069826 | 99.9% | 281.13 | C6H13NNaO8P | 10mg
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research Glycobiology studies the structure synthesis biology and evolution of sugars It involves carbohydrate chemistry enzymology of glycan formation and degradation protein-glycan recognition and the role of glycans in biological systems This field is closely related to basic research biomedicine and biotechnology[1]
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