Drug Standards
Cayman Chemical LenalIdomIde 100mg
A derivative of thalidomide; reduces TNF-α production in isolated human PBMCs and whole blood stimulated by LPS from S. minnesota (IC50s = 13 and 25 nM, respectively); has been used as a building block in the synthesis of PROTACs that induce the degradation of IKZF1 and IKZF3 in MM.1S cells; reduces vascularization and total microvascular length in a rat mesenteric window assay model at 250 mg/kg per day, p.o.
Medchemexpress LLC Ticagrelor impurity 25 | 1616703-93-5 | 96.9% | C25H30F2N6O5S | 100 MG
Ticagrelor impurity 25 is an impurity of Ticagrelor. It is for research use only.
- Molecular weight: 564.60
- Appearance: Solid
- Shipping at room temperature in continental US; may vary elsewhere
- Store at 4°C, protect from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protecting from light
Medchemexpress LLC Trans-latanoprost | 913258-34-1 | MFCD03411996 | 98.4% | C26H40O5 | 10MG
trans-Latanoprost is the trans isomer of latanoprost (5,6-trans-latanoprost) provided as a research-grade chemical reference for studies of glaucoma and elevated intraocular pressure. It has molecular formula C26H40O5, molecular weight 432.59, and is offered with a reported purity of 98.35% across multiple pack sizes for laboratory use.
- High reported purity (98.35%).
- Characterized for analytical and research applications.
- Applicable to glaucoma and ocular hypertension research.
- Available in multiple lab-friendly pack sizes.
- Provided with analytical characterization data for reproducible results.
Medchemexpress LLC Tenofovir Disoproxil | 201341-05-1 | 99.5% | 519.44 | 1 ML
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor. It is commonly used in research to treat HIV and chronic Hepatitis B.
- Nucleotide reverse transcriptase inhibitor
- Used to treat HIV
- Used to treat chronic Hepatitis B
- High purity of 99.5%
- Soluble in DMSO (≥ 38 mg/mL)
- Available as a 10 mM solution in DMSO
Medchemexpress LLC Abemaciclib Impurity 1 | 1231930-33-8 | 99.4% | C11H12BrFN2 | 1 G
Abemaciclib Impurity 1 (6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole) is a drug intermediate for the synthesis of various active compounds. This product is for research use only and has not been fully validated for medical applications.
- Target: Drug intermediate
- Pathway: Others
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- For research use only
Medchemexpress LLC Triprolidine hydrochloride monohydrate | 6138-79-0 | 99.9% | 50 MG
Triprolidine hydrochloride monohydrate is a first-generation antihistamine and an oral active histamine H1 antagonist. It can be used for the research of allergic rhinitis and exhibits spinal motor and sensory block in rats.
- First-generation antihistamine
- Oral active histamine H1 antagonist
- Can be used for allergic rhinitis research
- Exhibits spinal motor and sensory block in rats
Sigma Aldrich Fine Chemicals Biosciences Asiaticoside United States Pharmacopeia (USP) Reference Standard | 16830-15-2 | MFCD06642601 | 30MG
Asiaticoside United States Pharmacopeia (USP) Reference Standard | Mol Wt: 959.12 | 16830-15-2 | MFCD06642601 | 30MG
Sigma Aldrich Fine Chemicals Biosciences Bupivacaine Related Compound A United States Pharmacopeia (USP) Reference Standard | 1330172-81-0 | 50mg
Bupivacaine Related Compound A United States Pharmacopeia (USP) Reference StandardPurity: | MW: 290.44 | 1330172-81-0 | 50mg
Apexbio Technology LLC Isradipine (Dynacirc)(Synonyms: Dynacirc, Prescal, Lomir, PN 200-110, Isrodipine, (+/-)-Isradipine, Isradipex), 10mM (in 1mL DMSO), CAS: 75695-93-1.
Isradipine (Dynacirc CAS 75695-93-1) is a small molecule antagonist belonging to the dihydropyridine class of calcium channel blockers It functions primarily by inhibiting L-type voltage-gated calcium channels thereby decreasing intracellular calcium influx into cardiac and vascular smooth muscle cells This inhibitory effect relaxes vascular smooth muscle tissue leading to vasodilation and subsequent reduction in systemic blood pressure In biomedical research isradipine is studied for its potential neuroprotective properties related to calcium-mediated excitotoxicity offering implications for conditions associated with neuronal calcium imbalance
eMolecules 881487-77-0 | Medchem Express | KPT-6566 | 1mg | 489863088 | HY-123847 | 443.53 | C22H21NO5S2
Medchem Express | KPT-6566 | 1mg | 489863088 | HY-123847 | 881487-77-0 | 443.530 | C22H21NO5S2
Medchemexpress LLC Atazanavir (sulfate) | 229975-97-7 | 99.7% | 802.93 | 50 MG
Atazanavir sulfate is a highly selective and orally active HIV-1 protease inhibitor with blood-brain barrier permeability. It functions as both a substrate and inhibitor of CYP3A4, and also inhibits P-glycoprotein (P-gp). Additionally, it is a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. This compound has demonstrated the ability to inhibit cardiac fibrosis and hyperlipidemia, and induce malignant glioma cell death.
- Highly selective and orally active
- HIV-1 protease inhibitor
- Crosses the blood-brain barrier
- Inhibitor and substrate of CYP3A4
- Inhibits P-glycoprotein (P-gp)
- SARS-CoV 3CLpro inhibitor (IC50 of 3.49 μM)
- Inhibits cardiac fibrosis
- Inhibits hyperlipidemia
- Induces malignant glioma cell death
Sigma Aldrich Fine Chemicals Biosciences Pancuronium bromide Related Compound B United States Pharmacopeia (USP) Reference Standard | 41261-71-6 | 15MG
Pancuronium bromide Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 690.63 | 41261-71-6 | 15MG
Selleck Chemical LLC Fulvestrant 10mM/1mL 129453-61-8 ICI-182780, ZD 9238
Fulvestrant (ICI-182780, ZD 9238) is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Colchicine 64-86-8 500mg
Colchicine (CAS 64-86-8) is a small-molecule inhibitor targeting tubulin polymerization It binds directly to tubulin monomers disrupting their polymerization into microtubules (IC50 3 2 M) By preventing microtubule assembly colchicine interferes with spindle formation arresting cells in mitosis at metaphase thereby functioning as a mitotic inhibitor Additionally colchicine demonstrates anti-inflammatory activity by suppressing neutrophil motility and function reducing urate crystal deposition and has been effectively used in animal models of gouty arthritis It is widely utilized in biomedical research to study microtubule dynamics mitosis control and inflammatory pathways