Drug Standards
![Medchemexpress LLC 4H-imidazo[1,5-a]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo- | 84378-44-9 | 100.0% | 275.24 | C13H10FN3O3 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229210.png-250.jpg)
Medchemexpress LLC 4H-imidazo[1,5-a]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo- | 84378-44-9 | 100.0% | 275.24 | C13H10FN3O3 | 1 ML
Flumazenil acid is the carboxylic acid metabolite of flumazenil, provided as a high-purity reference material for research on GABAA receptor pharmacology and drug metabolism. It is supplied as a powder and is commonly prepared as a 10 mM solution (1 mL) for in vitro studies.
- High purity: 99.96% as reported by certificate of analysis.
- Molecular formula C13H10FN3O3 and molecular weight 275.24 g/mol.
- Available as powder; solutions commonly prepared at 10 mM, 1 mL volumes.
- Storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months) or -20 °C (1 month).
- Intended for research use in pharmacology and metabolism studies (in vitro).
Medchemexpress LLC Androgen receptor H 5ug
Recombinant partial fragment of the human androgen receptor (residues D551-T919) expressed in E. coli and supplied as a lyophilized powder with N-terminal His-SUMO and C-terminal Myc tags. The product is formulated in PBS (pH 7.4) with 5 mM DTT, exhibits >90% purity by reducing SDS-PAGE, has endotoxin <1 EU/μg, and is intended for biochemical and cell-based assays evaluating AR activity.
- Contains AR fragment corresponding to residues D551-T919.
- Expressed in E. coli and supplied as lyophilized powder.
- N-terminal His-SUMO and C-terminal Myc tags for detection and purification.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Formulated in PBS with 5 mM DTT; recommended storage at -20°C.
- Demonstrated biological activity with reported ED50 for inhibition of PC-3 cell migration.
Sigma Aldrich Fine Chemicals Biosciences Pioglitazone hydrochloride United States Pharmacopeia (USP) Reference Standard | 112529-15-4 | MFCD04975446 | 100MG
Pioglitazone hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 392.9 | 112529-15-4 | MFCD04975446 | 100MG
Cayman Chemical 5trans Latanoprost free acid
An isomer of latanoprost (free acid) wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E); intended primarily as an analytical standard
Sigma Aldrich Fine Chemicals Biosciences Dibenzosuberone European Pharmacopoeia (EP) Reference Standard | 1210-35-1 | MFCD00003587 |
Dibenzosuberone European Pharmacopoeia (EP) Reference Standard | Mol Wt: 208.26 | 1210-35-1 | MFCD00003587 |
Medchemexpress LLC Folic acid (disodium) | 29704-76-5 | 98.6% | 485.36 | 25 MG
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid with an intrinsic dissolution rate (IDR) of 4.96·10^5 g/s. It serves as a cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia.
- Orally active disodium salt form of folic acid.
- Serves as cofactor in single-carbon transfer reactions.
- Exhibits protective effects against neural tube defects, ischemic events, and cancer.
- Deficiency leads to megaloblastic anemia.
Medchemexpress LLC Neostigmine methyl sulfate | 51-60-5 | 98.9% | 100 MG
Neostigmine methyl sulfate (Standard) serves as an analytical standard, designed for research and analytical applications. This reference standard assay is widely utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Intended for research and analytical applications.
- Functions as a reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research.
- Suitable for techniques including HPLC, GC, and MS.
Apexbio Technology LLC Fostamatinib (R788) 901119-35-5 100mg
Fostamatinib (R788 CAS 901119-35-5) is an orally available small-molecule inhibitor targeting spleen tyrosine kinase (Syk) with an IC50 of approximately 41 nM As a prodrug fostamatinib is rapidly converted to its active metabolite R406 an ATP-competitive inhibitor of Syk (Ki 30 nM) R406 additionally inhibits related kinases such as Flt3 Lyn (IC50 63 nM) and Lck (IC50 37 nM) thereby modulating BCR- and Fc receptor-mediated signaling pathways Preclinical studies demonstrate activity of fostamatinib in various autoimmune and inflammatory models including SLE-related nephritis and dermatitis in MRL/lpr mice highlighting its utility as a research tool in autoimmune disease investigation
Apexbio Technology LLC Eltrombopag Olamine 496775-62-3 50mg
Eltrombopag Olamine is an orally bioavailable thrombopoietin receptor (c-mpl) agonist that directly stimulates platelet production through activation of the JAK2/STAT signaling pathway In cellular assays using murine BAF3 cells expressing human thrombopoietin receptor (hTpoR) eltrombopag induced STAT-dependent signaling responses with an EC50 value of approximately 0 27 M This compound promotes differentiation of human CD34 progenitor cells into megakaryocytes capable of platelet production Eltrombopag is commonly applied in hematological research particularly in studies involving thrombocytopenia and thrombopoiesis-related mechanisms
Medchemexpress LLC Afatinib impurity 33 | 2475094-87-0 | 10mg
Afatinib impurity 33 is an impurity of Afatinib (HY-10261)
Sigma Aldrich Fine Chemicals Biosciences Istradefylline | 155270-99-8 | MFCD00928421 | 5mg
Istradefylline | Purity: 0.98 | Mol Wt: 384.43 | 155270-99-8 | MFCD00928421 | 5mg
Medchemexpress LLC Cy3-cisplatin | 85.0% | 10 MG
Cy3-Cisplatin is a fluorescent conjugate linking a Cyanine 3 dye to cisplatin for imaging, tracking, and drug delivery research. Supplied as an orange to red solid, the compound shows ~85% purity and is unstable in solution, so freshly prepared solutions are recommended. Store at -20°C and protect from light.
- Fluorescent conjugate for imaging and tracking
- Suitable for drug delivery and fluorescent labeling
- Supplied as an orange to red solid
- Purity approximately 85.0%
- Store at -20°C and protect from light
- Unstable in solution; prepare fresh solutions before use
Medchemexpress LLC Quetiapine impurity 1 | 1076199-40-0 | MFCD11977896 | ≥98.0% | 399.51 g/mol | C21H25N3O3S | 10 MG
Quetiapine impurity 1 is a characterized impurity reference of quetiapine supplied as a solid analytical standard for laboratory research use only. It is intended for impurity profiling, method development, and stability studies where a defined, high-purity reference material is required.
- Suitable as an analytical reference standard for impurity profiling and method validation.
- Available in small measured packages for convenient analytical workflows.
- Solid powder form allows accurate weighing and dissolution for assays.
- High purity (≥98.0%) supports reliable chromatographic and spectrometric analyses.
- Recommended storage conditions provided to maintain compound stability.
![Alkali Scientific Gibberellic Acid A3 [GA3], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659950.jpg-250.jpg)
Alkali Scientific Gibberellic Acid A3 [GA3], 1 G
Gibberellic Acid A3 (GA3) is a plant growth regulator available in powder form, with a 1g package size. GA3 is used to promote cell elongation and germination in plant tissues, helping to overcome dormancy in seeds and stimulate growth in various plant species. It is widely used in plant tissue culture to enhance the growth of shoots, roots, and other plant structures. In addition to its applications in research, GA3 is used in the agricultural industry to increase crop yields and improve fruit development. The powder form allows for convenient storage and accurate preparation of solutions for laboratory and commercial use.
Apexbio Technology LLC Chlorambucil 305-03-3 10mM (in 1mL DMSO)
Chlorambucil (CAS 305-03-3) is an alkylating chemotherapeutic agent belonging to the nitrogen mustard class Its primary mechanism involves forming crosslinks within DNA strands both intra- and inter-strand crosslinks resulting in impaired DNA replication and transcription ultimately inducing cell death In vitro studies showed that chlorambucil potently inhibits human microvascular endothelial cells (IC 0 53 M) and exhibits cytotoxic activities against glioma cell lines such as SF767 (IC 114 M) and U87-MG (IC 96 M) Chlorambucil is widely used in research settings to investigate cell apoptosis DNA damage and lymphoid malignancies like chronic lymphocytic leukemia (CLL)