Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Escitalopram Related Compound A United States Pharmacopeia (USP) Reference Standard | 128173-53-5 | 10MG
Escitalopram Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 535.58 | 128173-53-5 | 10MG
Apexbio Technology LLC Lapatinib Ditosylate 388082-77-7 10mM (in 1mL DMSO)
Lapatinib Ditosylate (CAS 388082-77-7) is a reversible dual inhibitor of the ErbB-2 (HER2) and epidermal growth factor receptor (EGFR) tyrosine kinases It competitively binds to the ATP-binding sites of these receptors preventing activation and downstream signaling In vitro Lapatinib Ditosylate exhibits potent inhibition with IC50 values of 9 2 nM for ErbB-2 and 10 8 nM for EGFR and demonstrates over 300-fold selectivity compared to kinases such as MEK and ERK The compound suppresses proliferation and downstream phosphorylation events (Erk1/2 AKT) in cancer cell lines overexpressing ErbB-2/EGFR and induces G1 cell cycle arrest In vivo it reduces tumor growth in xenograft mouse models Lapatinib Ditosylate is widely utilized in studies exploring receptor tyrosine kinase function and targeted cancer therapies
Medchemexpress LLC (5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-trienoic acid-d11 | 99.9% | 349.55 | 25 UG
This product is a deuterated form of 11,12-DiHETrE, a dihydroxy metabolite of arachidonic acid. It features eleven deuterium atoms, making it suitable for use as an internal standard in mass spectrometry-based quantitative analysis. This high-purity compound is provided as a solution for research applications.
- High purity
- Isotopically labeled
- Suitable for mass spectrometry
- Stable in solution
- Research use only
Sigma Aldrich Fine Chemicals Biosciences Benperidol European Pharmacopoeia (EP) Reference Standard | 2062-84-2 |
Benperidol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 381.44 | 2062-84-2 |
Sigma Aldrich Fine Chemicals Biosciences Cefazolin United States Pharmacopeia (USP) Reference Standard | 25953-19-9 | 200MG
Cefazolin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 454.51 | 25953-19-9 | 200MG
Selleck Chemical LLC Dolutegravir (GSK1349572) 5mg 1051375-16-6 S/GSK1349572
Dolutegravir (GSK1349572, S/GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
![Alkali Scientific Augmentin [Amoxicillin, Sodium Salt/Potassium Clavulanate 5:1], 2 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Alkali Scientific Augmentin [Amoxicillin, Sodium Salt/Potassium Clavulanate 5:1], 2 G
Amoxicillin and Clavulanate is a combination antibiotic formulation widely used in microbiological and pharmaceutical research. Amoxicillin is a beta lactam antibiotic that inhibits bacterial cell wall synthesis, while clavulanate acts as a beta lactamase inhibitor that protects amoxicillin from enzymatic degradation by resistant bacteria. This combination provides broad spectrum antibacterial activity against both Gram positive and Gram negative organisms. In laboratory applications, it is used to study bacterial resistance mechanisms, antimicrobial susceptibility, and enzyme inhibition. The formulation is also used in cell culture and microbiology research where reliable inhibition of resistant bacterial strains is required.
Med Vet International Dynarex Suction Connection Tubing w/Male Connector, Non-Conductive, 3/16" x 6' and 3/16" x 18" Tube, 50/Case
Dynarex Resp-O2™ Suction Connecting Tubing is designed to provide secure connections to both portable and in-wall suction sources. This non-conductive Tubing features female connectors on both ends and includes an optional male (straw) adapter for additional attachments. Designed to connect suction sources to suction catheters and yankauers Constructed from transparent material for clear visualization during suctioning Durable, crush-resistant tubing Single-use and disposable Not made with natural rubber latex or DEHP
Cayman Chemical FlurbIprofen-d3 500ug
An internal standard for the quantification of flurbiprofen by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Metoclopramide impurity A European Pharmacopoeia (EP) Reference Standard | 5608-13-9 |
Metoclopramide impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.83 | 5608-13-9 |
Sigma Aldrich Fine Chemicals Biosciences Felypressin European Pharmacopoeia (EP) Reference Standard | 56-59-7 |
Felypressin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 1040.22 | 56-59-7 |
Sigma Aldrich Fine Chemicals Biosciences Hymecromone impurity B European Pharmacopoeia (EP) Reference Standard | 6320-42-9 |
Hymecromone impurity B European Pharmacopoeia (EP) Reference Standard | Mol Wt: 176.17 | 6320-42-9 |
Medchemexpress LLC Naproxen | 22204-53-1 | MFCD00078864 | C14H14O3 | 25 G
Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that acts as a COX-1 and COX-2 inhibitor, with IC50s of 8.72 and 5.15 μM respectively in cell assays. It is for research use only.
- Inhibits COX-1 and COX-2 enzymes
- High purity of 99.98%
- Target: COX and Autophagy
- Pathway: Immunology/Inflammation and Autophagy
- Stable for 3 years at room temperature
- Stable in solvent for 2 years at -80°C
Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 200 MG
Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity, demonstrating high selectivity for AChE over BuChE. It also exhibits neuroprotective effects against Aβ42 neurotoxicity. The neuroprotective mechanism involves enhanced phosphorylation of Akt and GSK-3β, and reduced phosphorylation of tau and glycogen synthase. Pharmacokinetic studies showed that Donepezil treatment significantly prevents scopolamine-induced memory impairment in mice.
- Reversible, selective AChE inhibitor
- IC50 of 6.7 nM for AChE activity
- High selectivity for AChE over BuChE
- Exhibits neuroprotective effect on Aβ42 neurotoxicity
- Enhances phosphorylation of Akt and GSK-3β
- Reduces phosphorylation of tau and glycogen synthase
- Significantly prevents scopolamine-induced memory impairment in mice
Cayman Chemical hydroxy BupropIon 10mg
An analytical reference standard categorized as an antidepressant; a metabolite of bupropion; substitutes for D-amphetamine in rats in a two-lever drug discrimination test; intended for research and forensic applications