Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Pancuronium bromide Related Compound C United States Pharmacopeia (USP) Reference Standard | 27115-86-2 | 15MG
Pancuronium bromide Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 690.63 | 27115-86-2 | 15MG
Medchemexpress LLC LY-2584702 (tosylate salt) | 1082949-68-5 | 99.5% | 617.62 | 10 MG
LY-2584702 tosylate salt is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In the S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM. It inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells and demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.
- Selective ATP competitive inhibitor of p70S6K.
- Inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells.
- Demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.
- Inhibits S6K activity in EOMA cells.
- Inhibits proliferation of A549 and SK-MES-1 cells.
Medchemexpress LLC Lenalidomide-4-aminomethyl hydrochloride | 444289-05-8 | MFCD32703223 | 90.9% | C14H16ClN3O3 | 10MG
Lenalidomide-4-aminomethyl hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ubiquitin ligase for targeted protein degradation. It is commonly employed as the E3-binding moiety in PROTAC construction and can be conjugated to target ligands via a synthetic linker; supplied as the hydrochloride salt to aid handling and solubility.
- Lenalidomide-based cereblon (CRBN) ligand for targeted protein degradation.
- Suitable for use as the E3-binding moiety in PROTAC design and synthesis.
- Hydrochloride salt form facilitates conjugation and handling in synthetic workflows.
- Reported purity 90.9%; verify certificate of analysis for critical applications.
- Provided for research use under appropriate laboratory safety conditions.
Selleck Chemical LLC Bazedoxifene (WAY-140424) HCl S2128-10mg
Bazedoxifene HCl (WAY-140424 TSE-424) is a novel non-steroidal indole-based estrogen receptor modulator (SERM) binding to both ER and ER with IC50 of 23 nM and 89 nM respectively
Sigma Aldrich Fine Chemicals Biosciences Drospirenone for peak identification European Pharmacopoeia (EP) Reference Standard | 67392-87-4 | MFCD00867350 |
Drospirenone for peak identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 366.49 | 67392-87-4 | MFCD00867350 |
U.S. Pharmacopeia Doxercalciferol, 54573-75-0, MFCD00871065, 2 x 20mg
Molecular formula C28H44O2, Molecular weight 412.65, Melting point/freezing point 296.6 - 307.4 °F (147 - 153 °C), Synonyms: 1alpha-Hydroxyergocalciferol, 1alpha-Hydroxyvitamin D2, (5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1’,3’-diol
Sigma Aldrich Fine Chemicals Biosciences Finasteride | 98319-26-7 | MFCD00869737 | 100 mg
Finasteride | Purity: ≥98% | Mol Wt: 372.54 | 98319-26-7 | MFCD00869737 | 100 mg
[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C | 50mg | 335409157](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2228207.JPG-250.jpg)
eMolecules 159989-65-8 | Nelfinavir Mesylate | Target Molecule | MFCD00931436 | 663.890 | C33H49N3O7S2 | 0.000 | CS(O)(=O)=O.Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C | 50mg | 335409157
Nelfinavir Mesylate | Target Molecule | 159989-65-8 | MFCD00931436 | 663.890 | C33H49N3O7S2 | 0.000 | CS(O)(=O)=O.Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C | 50mg | 335409157
Cayman Chemical Reduced HaloperIdol 25mg
An active metabolite of haloperidol; formed via reduction of haloperidol by ketone reductase; inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively); stimulates BDNF secretion from CCF-SSTG1 and U87MG astrocytic glial cells; inhibits norepinephrine, dopamine, and 5-HT reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters); increases latency to paw withdrawal in mouse models of capsaicin-induced mechanical hypersensitivity at 0.5 mg/kg
Apexbio Technology LLC Pyridostigmine Bromide 101-26-8 1g
Pyridostigmine Bromide (CAS 101-26-8) is a synthetic small molecule that functions as a reversible inhibitor of acetylcholinesterase By binding to the active site of the enzyme it impedes the hydrolysis of acetylcholine resulting in enhanced cholinergic transmission at neuromuscular junctions and within the parasympathetic nervous system Pyridostigmine is widely utilized in preclinical and clinical research to investigate cholinergic mechanisms model synaptic transmission and study disorders involving neuromuscular conduction Its application extends to the exploration of therapeutic approaches for diseases such as myasthenia gravis
Sigma Aldrich Fine Chemicals Biosciences D-Camphor sulfonic acid United States Pharmacopeia (USP) Reference Standard | 3144-16-9 | MFCD00064157 | 100MG
D-Camphor sulfonic acid United States Pharmacopeia (USP) Reference Standard | Mol Wt: 232.3 | 3144-16-9 | MFCD00064157 | 100MG
Medchemexpress LLC Hydroxy Itraconazole | 112559-91-8 | >99.8% | 1 MG
Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which functions as a triazole antifungal agent. This compound is intended for research use only.
- Active metabolite of Itraconazole
- Functions as a triazole antifungal agent
- Intended for research use
Medchemexpress LLC Capecitabine-2',3'-cyclic carbonate | 921769-65-5 | MFCD23160273 | 98.9% | 385.34 g·mol⁻¹ | C16H20FN3O7 | 50 MG
Capecitabine-2',3'-cyclic carbonate is a synthetic 5'-deoxy-5-fluorocytidine derivative supplied for laboratory research use only. It is provided as a powdered research reagent with supporting documentation for safe handling and quality verification.
- Purity (HPLC): 98.9%.
- Cas number: 921769-65-5.
- Molecular weight: 385.34 g·mol⁻¹.
- Molecular formula: C16H20FN3O7.
- Available sizes: 5 mg-200 mg (multiple vial sizes).
- Provided with certificate of analysis and safety data sheet.
- Intended for preclinical and in vitro anticancer research applications.
Sigma Aldrich Fine Chemicals Biosciences Baclofen Related Compound100MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards