Drug Standards
Apexbio Technology LLC Betahistine 2HCl 5579-84-0 5g
Betahistine 2HCl (CAS 5579-84-0) is a small-molecule inhibitor targeting histamine H3 receptors exhibiting an inhibitory concentration (IC50) of 1 9 M By antagonizing H3 receptors betahistine modulates histaminergic neurotransmission which influences the release of various neurotransmitters in the central nervous system This compound is widely utilized in research focused on the physiological roles of histamine signaling particularly in studies of neurological and vestibular disorders as well as in the exploration of H3 receptor pharmacology and modulation
Med Vet International Fluconazole Tablets (Diflucan), 100mg, 100ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Fluconazole tablets are a generic version of Diflucan. It belongs to a class of drugs called azole antifungals and should be stored at room temperature away from light and moisture.
Medchemexpress LLC 3-fluoro-4-phenylbenzoic acid | 137045-30-8 | MFCD05664334 | 216.21 | C13H9FO2 | 500 MG
Flurbiprofen impurity 3 is a research-grade impurity of the NSAID flurbiprofen supplied as an analytical standard for impurity profiling, method development, and reference studies. The substance is a solid with molecular formula C13H9FO2, molecular weight 216.21 Da, and CAS 137045-30-8. Store under the conditions specified in the certificate of analysis.
- Designed for impurity profiling and reference standard use.
- Suitable for analytical method development such as HPLC and LC-MS.
- Molecular formula C13H9FO2, molecular weight 216.21 Da, CAS 137045-30-8.
- Solid form; follow the certificate of analysis for storage and handling.
- Supplied in laboratory-scale quantities for analytical applications.
Medchemexpress LLC Folic acid (Vitamin B9) | 59-30-3 | 99.0% | 441.40 | 50 G
Folic acid (Vitamin B9) is an orally active essential nutrient from the B complex group of vitamins. It exhibits an antidepressant-like effect and its sodium form reduces the risk of neonatal neural tube defects. It is used in the research of megaloblastic and macrocytic anemias due to folic deficiency.
- Orally active essential nutrient from the B complex group of vitamins.
- Shows antidepressant-like effect.
- Sodium form reduces the risk of neonatal neural tube defects.
- Can be used for research on megaloblastic and macrocytic anemias due to folic deficiency.
- Plays a critical role in the prevention of chromosome breakage and hypomethylation of DNA.
Apexbio Technology LLC Moxifloxacin(Synonyms: Avelox, Vigamox, Avalox, Moxeza, Proflox, Octegra, MXF, BAY 12-8039), 50mg, CAS: 151096-09-2.
Moxifloxacin (CAS 151096-09-2) is a fluoroquinolone antibiotic targeting bacterial DNA gyrase an enzyme essential for DNA replication and transcription It demonstrates broad-spectrum antibacterial activity through inhibition of this enzyme Research indicates that Moxifloxacin exerts dose-dependent antiproliferative and cytotoxic effects in mammalian cell models with concentrations between 50 and 1500 g/mL significantly impacting cell viability and inducing morphological damage such as binucleation Animal studies show intravenous administration (100 mg/kg rats) elevates blood glucose and serum adrenaline levels accompanied by enhanced histamine release but no effect was noted at 75 mg/kg Therefore Moxifloxacin is valuable in biomedical studies exploring antibiotic toxicity cellular proliferation and metabolic responses
Apexbio Technology LLC Milrinone 78415-72-2 10mM (in 1mL DMSO)
Milrinone (CAS 78415-72-2) is a selective inhibitor of phosphodiesterase 3 (PDE3) demonstrating an IC50 of 56 12 nM for PDE3 inhibition It acts on both PDE3A localized predominantly in cardiac tissue vascular smooth muscle and platelets and PDE3B found in adipose tissue liver and pancreatic islets Milrinone increases intracellular cAMP levels in platelets with an EC50 of 5329 970 nM leading to enhanced contractility and vasodilation effects This profile supports its utility in cardiovascular research and metabolic studies involving cAMP-mediated signaling pathways
Medchemexpress LLC Lenalidomide-F | 2359705-88-5 | MFCD31556181 | 99.4% | 262.24 g/mol | C13H11FN2O3 | 50 MG
Lenalidomide-F is an E3 ligase ligand (cereblon binder) used in targeted protein degradation research and PROTAC synthesis. It recruits cereblon to enable proteasome-dependent degradation of target proteins and is supplied as a solid research reagent for in vitro and in vivo studies.
- High purity (reported ~99.4%).
- Molecular weight: 262.24 g/mol.
- Chemical formula: C13H11FN2O3.
- Soluble in DMSO to 5 mg/mL; may require ultrasonic warming to 60°C.
- Stable at room temperature for years; in solution store at -80°C or -20°C per guidance.
- Available in multiple pack sizes (25 mg-1 g; larger quantities available on request).
Sigma Aldrich Fine Chemicals Biosciences Salbutamol impurity J European Pharmacopoeia (EP) Reference Standard | 156547-62-5 (free base) |
Salbutamol impurity J European Pharmacopoeia (EP) Reference Standard | Mol Wt: 237.29 | 156547-62-5 (free base) |
Medchemexpress LLC Pantoprazole (sodium) | 138786-67-1 | 99.8% | 405.35 | 25 MG
Pantoprazole sodium is an orally active and potent proton pump inhibitor (PPI). This substituted benzimidazole acts as a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. It improves pH stability and exhibits anti-secretory and anti-ulcer activities. Additionally, it has been shown to significantly increase tumor growth delay when combined with Doxorubicin.
- Orally active and potent proton pump inhibitor.
- Potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM.
- Improves pH stability.
- Possesses anti-secretory and anti-ulcer activities.
- Increases tumor growth delay in combination with Doxorubicin.
U.S. Pharmacopeia Polyoxyl 35 Castor Oil, 61791-12-6, MFCD00130879, 1g
Dynamic viscosity 1318.51 mPa.s (73.4 °F (23 °C)), Flash point > 212.0 °F (> 100.0 °C), Chemical name: Polyoxyethylenglycerol triricinoleate 35
Medchemexpress LLC Bufexamac | 2438-72-4 | MFCD00078936 | 98.0% | 1 ML
Bufexamac is a selective Ⅱb HDAC (HDAC6, HDAC10) and LTA4H dual inhibitor, with Kds of 0.53 μM and 0.22 μM for HDAC6 and HDAC10. It is also a nonsteroidal anti-inflammatory drug. This product is for research use only.
- Acts as a dual inhibitor for HDAC6, HDAC10, and LTA4H with specific Kd values.
- Functions as a nonsteroidal anti-inflammatory drug.
- Inhibits the secretion of IFN-α in peripheral blood mononuclear cells.
- Inhibits HDAC10 to block autophagic flux in BE(2)-C cells.
- Inhibits neutrophil chemotaxis by inhibiting LTA4H-mediated endogenous LTB4 biosynthesis.
- Inhibits lysine deacetylases (KDACs) at lower concentrations.
- Ameliorates LPS-induced acute lung injury in mice by targeting LTA4H.
- Did not cause untoward systemic or local effects in healthy horses during intra-articular injections.
Selleck Chemical LLC Diethylstilbestrol 50mg 56-53-1 Stilbestrol
Diethylstilbestrol (Stilbestrol) is a synthetic nonsteroidal estrogen, used to prevent miscarriage and other pregnancy complications. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Polyvinylpyrrolidone for molecular biology, nucleic acid hybridization tested, mol wt 360,000 | 9003-39-8 | MFCD00149016 | 100G
Polyvinylpyrrolidone for molecular biology, nucleic acid hybridization tested, mol wt 360,000 | 9003-39-8 | MFCD00149016 | 100G
Medchemexpress LLC Bupropion morpholinol-d6 | 1216893-18-3 | 99.3% | 1 MG
Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol, a major metabolite of Bupropion. It inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro, contributing to antidepressant and smoking cessation activities.
- Can be used as a tracer.
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits dopamine and norepinephrine transporters.
- Inhibits the α4β2 nicotinic receptor in vitro.
- Contributes to antidepressant and smoking cessation activities.
- For research use only.