Ion Chromatography Standards
Apexbio Technology LLC Nafcillin Sodium 7177-50-6 1g
Nafcillin Sodium (7177-50-6) is a small-molecule inhibitor targeting -lactamase It is designed to reversibly inhibit -lactamase thereby preventing bacterial resistance mediated by hydrolysis of -lactam antibiotics Nafcillin Sodium exerts its biological activity primarily through reversible inhibition of -lactamase In in vitro studies Nafcillin Sodium demonstrates inhibitory activity with an IC50 value of approximately 33 mM Based on these pharmacological properties Nafcillin Sodium holds research potential in investigating -lactamase-mediated antibiotic resistance mechanisms evaluating therapeutic combination strategies and studying bacterial susceptibility profiles
Apexbio Technology LLC Lansoprazole 103577-45-3 1g
Lansoprazole (103577-45-3) is a small-molecule inhibitor targeting gastric H K -ATPase an enzyme responsible for gastric acid secretion via proton pump activity It is designed to inhibit H K -ATPase activity thereby suppressing gastric acid production Lansoprazole exerts its biological activity primarily through selective inhibition of the H K -ATPase enzyme In experimental models lansoprazole demonstrates inhibitory activity with an IC50 value of approximately 6 3 M for enzyme activity and 0 09 M for suppression of histamine-stimulated gastric acid secretion Based on these pharmacological properties lansoprazole holds research potential in studies of gastric acid-related pathophysiology gastroprotective mechanisms and ulcer formation processes
Apexbio Technology LLC Cefdinir 91832-40-5 1g
Cefdinir (91832-40-5) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby obstructing the final transpeptidation step of peptidoglycan formation Cefdinir exerts its biological activity primarily through PBP binding-mediated inhibition of cell wall biosynthesis In microbiological assays Cefdinir demonstrates antibacterial inhibition with reported IC50 values ranging from approximately 0 5 to 4 g/mL against susceptible bacteria Based on these pharmacological properties Cefdinir holds research potential in antibacterial susceptibility testing determination of minimum inhibitory concentrations (MIC) and investigation of antibiotic resistance mechanisms
Apexbio Technology LLC Mepiroxol 6968-72-5 1g
Mepiroxol is a small-molecule compound characterized by its ability to form specific interactions with target proteins It engages in salt bridge interactions with arginine residues (such as Arg-153 and Arg-74) and participates in hydrogen bonding via its hydroxyl group with protein residues like Asp-50 and Gly-96 supporting enhanced binding affinity Researchers utilize Mepiroxol for investigations into protein-ligand interaction mechanisms aiding structural biology analyses and guiding drug-design efforts
Apexbio Technology LLC Oxeladin Citrate 52432-72-1 1g
Oxeladin citrate (CAS 52432-72-1) is a small-molecule agonist targeting sigma-1 receptors It is designed to selectively activate sigma-1 receptors thereby modulating neural signaling pathways involved in cough reflex regulation neuroprotection pain perception and respiratory control Oxeladin citrate exerts its biological activity primarily through sigma-1 receptor agonism It exhibits an affinity (Ki) of approximately 25 nM for the sigma-1 receptor Based on these pharmacological properties Oxeladin citrate holds research potential in investigating cough suppression respiratory function and pathophysiological conditions associated with central nervous system pulmonary dysfunction and cerebrovascular disorders
SPEX CERTIPREP LLC 3P 100PPM PHOSPHOROUS KH2PO4 IC
(HPS by Zeptometrix) 100 ug/mL Phosphorus from KH2PO4 in H2O; Single Component IC Standard, 18 Month Expiry Date. Prepared from high-purity salts in 18-megaohm water, packaged in HDPE bottles.
SPEX CERTIPREP LLC 3P PHOSPHATE 250ML 1000PPM
(HPS by Zeptometrix) 1000 ug/mL Phosphate in H2O; Single component IC Standard, 18 month expiry date. Prepared from high-purity salts in 18-megaohm water, packaged in HDPE bottles.
Apexbio Technology LLC PNPP 4264-83-9 1g
PNPP (4264-83-9) is a chromogenic non-proteinaceous substrate utilized to assess phosphatase activity It is designed to serve as an analytical reagent for quantifying the activity of alkaline or acid phosphatases through enzymatic hydrolysis resulting in the formation of para-nitrophenol a yellow product with measurable absorbance PNPP exerts its application primarily through substrate conversion upon phosphatase-mediated hydrolysis Based on these properties PNPP holds research potential in enzymatic assays enzyme kinetics studies and the investigation of signal transduction pathways and enzyme-mediated biological processes in biomedical laboratories
Apexbio Technology LLC Asenapine 85650-56-2 1g
Asenapine (CAS 85650-56-2) is a small-molecule psychotropic agent characterized by high-affinity antagonism at multiple neurotransmitter receptors including several serotonin (5-HT) dopamine noradrenaline and histamine receptor subtypes (with reported pK sub i /sub values in the high nanomolar to sub-nanomolar range such as 8 60 8 40 10 15 9 75 and 10 46) This broad receptor antagonism profile underlies its capacity to modulate neurotransmission in various central nervous system pathways Asenapine is widely employed in biomedical research to investigate the pharmacological basis of antipsychotic activity and to study the functional roles of monoaminergic and histaminergic signaling in psychiatric and neuropharmacological models
Apexbio Technology LLC Abametapir 1762-34-1 1g
Abametapir (CAS 1762-34-1) is a small-molecule inhibitor targeting metalloproteinases It is designed to inhibit metalloproteinase enzymes involved in the egg hatching and survival processes of lice Abametapir exerts its biological activity primarily through inhibition of metalloproteinases In in vitro assays abametapir demonstrates ovicidal activity with reported IC50 values approximately in the low micromolar range Based on these pharmacological properties abametapir holds research potential in the management of head lice infestations and laboratory studies on ectoparasite enzyme inhibition and resistance development
Apexbio Technology LLC Coenzyme Q0 605-94-7 1g
Coenzyme Q0 (CAS 605-94-7) is a quinone derivative originally derived from cinnamon extract It modulates multiple cellular pathways by inducing apoptosis and autophagy primarily through inhibition of the HER-2/AKT/mTOR signaling cascade Additionally Coenzyme Q0 regulates transcription factors such as NF B and AP-1 enhances Nrf2 stability and mitigates inflammation and oxidative stress Its anti-angiogenic properties are mediated via downregulation of the MMP-9/NF- B pathway and upregulation of HO-1 signaling Coenzyme Q0 is widely used in basic research and drug development targeting cancer inflammation and angiogenesis-related disorders