Ion Chromatography Standards
Apexbio Technology LLC Pasiniazid 2066-89-9 1g
Pasiniazid (CAS 2066-89-9) is a small-molecule inhibitor targeting enzymes essential for mycolic acid biosynthesis in mycobacteria It is designed to disrupt cell wall synthesis thereby inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium leprae Pasiniazid exerts its biological activity primarily through inhibition of mycolic acid biosynthesis In in vitro antimicrobial assays and animal infection models Pasiniazid demonstrates inhibitory activity with reported IC50 values against mycobacterial targets typically within micromolar concentrations Based on these pharmacological properties Pasiniazid holds research potential in the investigation of tuberculosis and leprosy pathogenesis including studies on drug-response relationships resistance mechanisms and pharmacokinetics
Apexbio Technology LLC Progesterone 57-83-0 1g
Progesterone (57-83-0) is a steroid hormone that modulates reproductive processes by specifically interacting with its nuclear receptors It is designed to regulate embryo implantation and endometrial physiology thereby influencing estrogenic signaling and target gene expression in reproductive tissues Progesterone exerts its biological activity primarily through attenuation of estrogenic signaling affecting genes such as Egr1 In in vitro studies progesterone demonstrates the ability to restrict cell proliferation pathways in melanoma models including B16F10 mouse cells and BLM human cell lines Additionally progesterone regulates mammary carcinoma progression via RANKL-dependent activation of signaling components such as GLI-1 Based on these pharmacological properties progesterone holds research potential in studies of hormonal regulation reproductive biology cancer progression and neuroprotection
Apexbio Technology LLC Lamotrigine 84057-84-1 1g
Lamotrigine (CAS 84057-84-1) is a small molecule anticonvulsant that acts primarily as a voltage-gated sodium channel blocker stabilizing neuronal membranes and inhibiting repetitive neuronal firing Research indicates that lamotrigine inhibits serotonin (5-HT) uptake with reported IC50 values of 240 M in human platelets and 474 M in rat brain synaptosomes These dual actions on sodium channels and 5-HT transport underline its utility in studies investigating the modulation of excitatory neurotransmission and synaptic function in neurological and psychiatric conditions
Apexbio Technology LLC Ibuprofen 15687-27-1 1g
Ibuprofen (CAS 15687-27-1) is a small-molecule inhibitor targeting cyclooxygenase enzymes COX-1 and COX-2 It is designed to inhibit prostaglandin prostacyclin and thromboxane biosynthesis thereby regulating inflammation and pain pathways Ibuprofen exerts its biological activity primarily through COX enzyme inhibition In cell-based studies ibuprofen demonstrates anti-proliferative activity with an IC50 value of approximately 12 M for COX-1 and 80 M for COX-2 in relevant experimental models including human colon carcinoma HCT-116 cells Based on these pharmacological properties ibuprofen holds research potential in inflammation studies oncology lipid metabolism and neurobiology
Apexbio Technology LLC Acetarsone 97-44-9 1g
Acetarsone (97-44-9) is a small-molecule anti-infective and antiparasitic agent belonging to the organoarsenic group of compounds It is proposed to modulate parasite-specific metabolic enzymes or interfere with biochemical pathways essential for parasite survival Acetarsone exerts its biological activity primarily through inhibition of parasite biochemical pathways however the exact molecular targets and mechanism remain to be fully elucidated In both in vitro and in vivo studies acetarsone demonstrates antiparasitic activity with IC50 values reported in the low to moderate micromolar range depending on parasite species and experimental conditions Based on these pharmacological properties acetarsone holds research potential in the treatment of protozoan infections and in studies of intestinal inflammation and mucosal pathology
Aqua Solutions Inorganic Carbon Standard 1,000 ppm Certified Solution (500ML)
Inorganic Carbon Standard 1,000 ppm Certified Solution (500ML)
Thermo Scientific Dionex™ Retention Time Standards for Ion Chromatography
For Use With Routine Anion Determinations | Type: Standard | Standard Components Fluoride 2 mg/L, Chloride 24 mg/L, Nitrite 16 mg/L, Bromide 36 mg/L, Nitrate36 mg/L, Phosphate 26 mg/L, Sulfate 40 mg/L | Volume (Metric) 50 mL
Apexbio Technology LLC LAP 85073-19-4 1g
Lithium phenyl-2 4 6-trimethylbenzoylphosphinate (LAP CAS 85073-19-4) is a photoinitiator that generates free radicals upon exposure to light Through this radical formation LAP facilitates photopolymerization reactions commonly employed in biomedical research such as the fabrication of hydrogels for 3D bioprinting applications The free radicals produced by LAP can exert cytotoxic and potentially mutagenic effects under experimental conditions necessitating careful optimization in cell-based assays LAP is widely utilized for controlled light-mediated crosslinking in tissue engineering and biofabrication studies
Apexbio Technology LLC L-Phenylephrine 59-42-7 1g
L-Phenylephrine (CAS 59-42-7) is a selective agonist of the adrenergic 1A receptor exhibiting a Ki of 1 4 M with markedly lower affinity for 1B (Ki 23 9 M) and 1C (Ki 47 8 M) subtypes In vitro L-Phenylephrine has been shown to reduce apoptosis in neonatal rat cardiomyocytes following hypoxia and serum deprivation and to stimulate proliferation in neural progenitor cells It also increases the cross-sectional area and modulates gene expression in rat neonatal cardiomyocytes In vivo local administration in rats induces cutaneous anesthesia through 1-adrenergic receptor activation and clinical data suggest oral administration reduces nasal airway resistance These properties make L-Phenylephrine a valuable tool for studying 1A-adrenergic receptor-mediated cellular responses
Apexbio Technology LLC MCPA 94-74-6 1g
MCPA (CAS nan) is a small-molecule herbicide that modulates plant growth-regulating enzymes thereby disrupting physiological processes necessary for weed proliferation MCPA exerts its biological activity primarily through targeted enzymatic regulation involved in plant growth Experimental studies have demonstrated herbicidal activity of MCPA against various broadleaf species such as poppy thistle and reed plants Based on these pharmacological properties MCPA holds research potential in plant physiological investigations crop management research and the exploration of herbicide mechanisms at biochemical and molecular levels
Apexbio Technology LLC Fluocinonide 356-12-7 1g
Fluocinonide (CAS 356-12-7) is a synthetic glucocorticoid steroid targeting intracellular glucocorticoid receptors (GR) It is designed to modulate gene transcriptional activity thereby regulating the production and release of inflammatory cytokines and mediators in the inflammatory response pathway Fluocinonide exerts its biological activity primarily through binding to glucocorticoid receptors and forming receptor-ligand complexes which influence cellular and molecular inflammatory signaling cascades Based on these pharmacological properties fluocinonide holds research potential in studying pathophysiological mechanisms of inflammatory skin conditions evaluating topical corticosteroid metabolism and absorption and facilitating investigations focused on dermatological inflammatory responses
Apexbio Technology LLC Bifonazole 60628-96-8 1g
Bifonazole (60628-96-8) is a small-molecule inhibitor targeting sterol 14 -demethylase It is designed to block this enzyme thereby impairing ergosterol biosynthesis critical to fungal membrane structure and function Bifonazole exerts its biological activity primarily through inhibition of sterol 14 -demethylase In in vitro studies Bifonazole demonstrates antifungal inhibitory activity with reported IC50 values generally ranging from 0 5 to 4 g/mL depending on fungal species and experimental conditions Based on these pharmacological properties Bifonazole holds research potential in antifungal efficacy evaluation and mechanism-specific assays targeting sterol biosynthesis and membrane disruption
Waters Corp Waters Silica, Ion Calibration Standard, 1000 mg/L, 125 mL, Liquid
This Silica, Ion Calibration Standard is a 1000 mg/L liquid formulation. It is designed for use in primary calibration or for preparing second source calibration check standards.
- Can be used for primary calibration or to prepare second source calibration check standards.
- Traceable to NIST Standard Reference Materials (where available).
- Guaranteed stable for one year.
SPEX CERTIPREP LLC 3P FLORIDE 250ML 1000PPM
(HPS by Zeptometrix) 1000 ug/mL Fluoride in H2O; Single Component IC Standard, 18 Month Expiry Date. Prepared from high-purity salts in 18-megaohm water, packaged in HDPE bottles.
SPEX CERTIPREP LLC 3P CHLORIDE 250 ML 1000PPM
(HPS by Zeptometrix) 1000 ug/mL Chloride in H2O; Single Component IC Standard, 18 Month Expiry Date. Prepared from high-purity salts in 18-megaohm water, packaged in HDPE bottles.