Acetylides
eMolecules 3-Chloro-5-(trifluoromethoxy)phenol | 1017778-52-7 | MFCD09832330 | 1g
Apollo Scientific | 3-Chloro-5-(trifluoromethoxy)phenol | 1g | 562452639 | PC302050 | 98.000 | 1017778-52-7 | MFCD09832330 | 212.550 | C7H4ClF3O2
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eMolecules Building Block Tool
Medchemexpress LLC Propargyl-PEG12-OH 50mg | 1036204-61-1 | 584.69 | C27H52O13 | 50 MG
Propargyl-PEG12-OH is a PEG12-based linker bearing a terminal propargyl (alkyne) group and a hydroxyl terminus, intended for use as a click-chemistry-compatible spacer in PROTAC synthesis and bioconjugation. It has a molecular weight of 584.69 and CAS 1036204-61-1, and is supplied as a small laboratory vial.
- Terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- PEG12 spacer increases flexibility and aqueous solubility.
- Hydroxyl terminus enables further functionalization or conjugation.
- Analytical purity ≥98.0% (NMR) suitable for synthetic applications.
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years).
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 10 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG8-bromide | 2055046-25-6 | MFCD29042377 | 95.0% | 471.38 | C19H35BrO8 | 250 MG
Propargyl-PEG8-bromide is a bifunctional PEG-based reagent containing a terminal alkyne and a bromide leaving group, used as a non-cleavable linker in antibody-drug conjugate (ADC) and PROTAC synthesis and as a reagent for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Contains a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Contains a PEG8 spacer to increase solubility and flexibility.
- Contains a bromide leaving group for nucleophilic substitution reactions.
- Functions as a non-cleavable linker suitable for ADC and PROTAC assembly.
- Molecular weight approximately 471.4 and formula C19H35BrO8.
- Typically supplied in mg-scale quantities for research use.
eMolecules 1129-65-3 | 1-Phenyl-1-hexyne | Ambeed | MFCD00039969 | 158.244 | C12H14 | 98.000 | CCCCC#Cc1ccccc1 | 250mg | 517263003
1-Phenyl-1-hexyne | Ambeed | 1129-65-3 | MFCD00039969 | 158.244 | C12H14 | 98.000 | CCCCC#Cc1ccccc1 | 250mg | 517263003
eMolecules 1703955-84-3 | 5-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific267.180 | C10H9F4NO3 | 95.000 | NC(Cc1cc(F)ccc1OC(F)(F)F)C(O)=O | 1g | 562457991
5-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | 1703955-84-3267.180 | C10H9F4NO3 | 95.000 | NC(Cc1cc(F)ccc1OC(F)(F)F)C(O)=O | 1g | 562457991
Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 98.0% | 163.01 g/mol | C5H7BrO | 250 MG
Propargyl-PEG1-bromide is a PEG-derived reagent bearing a propargyl (alkynyl) group and a terminal bromide. It serves as a reactive building block for introducing a short PEG1 spacer with an alkyne handle in synthesis workflows for chemical biology, bioconjugation, and drug delivery linker development.
- Small PEG spacer with propargyl functional group.
- Terminal bromide for alkylation or nucleophilic substitution reactions.
- Compatible with click chemistry and linker installation workflows.
- Useful for drug delivery and bioconjugation research applications.
- Molecular weight 163.01 g/mol.
- Chemical formula C5H7BrO.
- CAS number 18668-74-1.
- Typical purity 98.0%.
Medchemexpress LLC Propargyl-PEG4-Boc | 1355197-66-8 | 316.39 | 1 G
Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
eMolecules 1066-54-2 | Trimethylsilylacetylene | Chem-Impex | MFCD00008569 | 98.220 | C5H10Si | 99.000 | C[Si](C)(C)C#C | 1kg | 112760621
Trimethylsilylacetylene | Chem-Impex | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 99.000 | C[Si](C)(C)C#C | 1kg | 112760621
Medchemexpress LLC 5-(Boc-amino)-1-pentanol | 75178-90-4 | MFCD01862955 | ≥97.0% | 203.28 g/mol | C10H21NO3 | 25 G
5-(Boc-amino)-1-pentanol is a Boc-protected amino alcohol used as a versatile linker and intermediate in organic synthesis and medicinal chemistry. It features a tert-butoxycarbonyl (Boc) protected amine and a primary hydroxyl group that permit orthogonal functionalization - the hydroxyl can be derivatized or replaced, and the Boc group can be removed under mild acidic conditions to reveal the free amine.
- Contains a Boc-protected amine and a primary hydroxyl.
- Enables orthogonal functionalization for multi-step syntheses.
- Hydroxyl group suitable for derivatization or conjugation reactions.
- Boc group deprotects under mild acidic conditions to yield free amine.
- High purity (≥97%) appropriate for research applications.
- Solid material stable at room temperature with defined solvent storage conditions.
Medchemexpress LLC Bis-propargyl-PEG11 | 1351373-49-3 | 99.79% | 578.69 | 250 MG
Bis-propargyl-PEG11 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- Click chemistry reagent with an Alkyne group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
Medchemexpress LLC Bis-propargyl-PEG1 | 40842-04-4 | 98.0% | 138.16 | 100 MG
Bis-propargyl-PEG1 is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Suitable for PROTAC synthesis
Medchemexpress LLC Propargyl-PEG6-NHS ester | 2093153-99-0 | 98.0% | 445.46 g/mol | C20H31NO10 | 250 MG
Propargyl-PEG6-NHS ester is an alkyne-functionalized polyethylene glycol (PEG6) N-hydroxysuccinimide (NHS) ester used for bioconjugation and linker synthesis. It reacts with primary amines to form stable amide bonds and provides an alkyne handle suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
- Amine-reactive NHS ester for stable amide bond formation.
- Alkyne handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Peg6 spacer to improve solubility and reduce steric hindrance.
- High purity suitable for synthetic bioconjugation workflows.
- Available in small pack sizes for laboratory-scale synthesis.