Acetylides
Medchemexpress LLC Propargyl-O-C1-amido-PEG4-C2-NHS ester | 2101206-92-0 | 95.0% | 458.46 g/mol | C20H30N2O10 | 10 MG
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a propargyl-functionalized PEG4 spacer bearing an N-hydroxysuccinimide (NHS) ester. It is used as a bioconjugation reagent for click-chemistry and linker construction, and is reactive toward primary amines. Store cold and dry to preserve NHS ester reactivity.
- Propargyl (alkyne) functional group for click chemistry.
- NHS ester reactive toward primary amines for conjugation.
- Four-unit PEG spacer for increased solubility and spacing.
- Molecular weight 458.46 g/mol.
- Purity 95.0%.
- Recommended storage: pure form at -20°C; in solvent at -80°C or -20°C.
Medchemexpress LLC Propargyl-PEG7-NHS ester | 2093152-77-1 | MFCD29041936 | >95.0% | 489.51 g/mol | C22H35NO11 | 1 G
Propargyl-PEG7-NHS ester is an alkyne-functional PEG7 N-hydroxysuccinimide (NHS) ester used as a bifunctional linker for bioconjugation. It couples to primary amines via NHS chemistry and provides a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition, making it suitable for ADC, PROTAC, and general labeling applications.
- Alkyne-functional terminal enables click chemistry.
- NHS ester reacts with primary amines for covalent coupling.
- PEG7 spacer increases solubility and provides flexibility.
- Molecular weight about 489.51 g/mol and formula C22H35NO11.
- Typical applications include ADC linkers, PROTAC synthesis, and peptide or protein labeling.
Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | 5 G
Propargyl-PEG6-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing Azide groups.
- Peg-based protac linker for protac synthesis.
- Cleavable adc linker for antibody-drug conjugate synthesis.
- Click chemistry reagent containing an alkyne group.
- Enables copper-catalyzed azide-alkyne cycloaddition (cuaac) with azide groups.
STA Pharmaceutical 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 250 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Click chemistry reagent
- Alkyne group for reactions
- Used in PROTAC synthesis
- Applicable in cancer research
- Supports cancer targeted therapy
- PROTAC linker
Medchemexpress LLC Tert-butyl (5-hydroxypentyl)carbamate | 75178-90-4 | MFCD01862955 | ≥95.0% | 203.28 g/mol | C10H21NO3 | 5 G
Tert-butyl (5-hydroxypentyl)carbamate is a Boc-protected amino alcohol used as a synthetic building block and linker in organic and medicinal chemistry. The molecule combines an acid-labile Boc-protected amine with a terminal hydroxyl, allowing selective deprotection and subsequent functionalization for conjugation or further synthesis.
- Boc-protected amine removable under mild acidic conditions.
- Terminal hydroxyl enables esterification, etherification, or activation for coupling.
- Useful as a bifunctional building block for organic and medicinal chemistry.
- Molecular weight 203.28 g/mol; formula C10H21NO3.
eMolecules 1206972-45-3 | 2-Chloro-5-(trifluoromethoxy)pyridine | MFCD18257007 | 1g
Ambeed | 2-((Tetrahydro-2H-pyran-4-yl)oxy)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)benzonitrile | 100mg | 602852409 | A728926 | 1292317-54-4 | MFCD22393670 | 329.200 | C18H24BNO4
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eMolecules Building Block Tool
eMolecules 2112737-25-2 | Propargyl-PEG10-amine | Broadpharm | MFCD30730361 | 495.610 | C23H45NO10 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 347153785
Propargyl-PEG10-amine | Broadpharm | 2112737-25-2 | MFCD30730361 | 495.610 | C23H45NO10 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 347153785
![eMolecules 7758-99-8 | Copper(II) sulfate pentahydrate | Chem-Impex | MFCD00149681 | 249.680 | CuH10O9S | 99.000 | O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O | 100kg | 386903341](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130851.jpg-250.jpg)
eMolecules 7758-99-8 | Copper(II) sulfate pentahydrate | Chem-Impex | MFCD00149681 | 249.680 | CuH10O9S | 99.000 | O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O | 100kg | 386903341
Copper(II) sulfate pentahydrate | Chem-Impex | 7758-99-8 | MFCD00149681 | 249.680 | CuH10O9S | 99.000 | O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O | 100kg | 386903341
Aobchem 3-Butyn-2-ol 4-(2-chlorophenyl)- | 95% | CAS 893746-84-4 | C10H9ClO | 1g
3-Butyn-2-ol 4-(2-chlorophenyl)- | 95% | CAS 893746-84-4 | C10H9ClO | 1g
Aobchem 3-Butyn-2-ol 4-(2-chlorophenyl)- | 95% | CAS 893746-84-4 | C10H9ClO | 250mg
3-Butyn-2-ol 4-(2-chlorophenyl)- | 95% | CAS 893746-84-4 | C10H9ClO | 250mg
Medchemexpress LLC 4-pentynoic acid, 2,5-dioxo-1-pyrrolidinyl ester | 132178-37-1 | 99.8% | 195.17 g/mol | C9H9NO4 | 250 MG
Propargyl-C1-NHS ester is an N-hydroxysuccinimide (NHS) ester bearing a propargyl (alkyne) handle used as a non-cleavable linker and click-chemistry reagent for antibody-drug conjugation and general bioconjugation. It couples to primary amines via NHS-ester chemistry and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing partners.
- Alkyne-functional NHS ester for click chemistry
- Suitable for antibody-drug conjugation and bioconjugation workflows
- Reacts with primary amines via NHS ester coupling
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC)
- High purity and available in multiple pack sizes, including 250 mg
- Soluble in DMSO; store sealed, away from moisture and light
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) hex-5-ynoate | 906564-59-8 | MFCD28898858 | 97.0% | 209.20 g/mol | C10H11NO4 | 50 MG
Propargyl-C2-NHS ester is an alkyne-containing N-hydroxysuccinimide (NHS) ester used for bioconjugation. It serves as a non-cleavable linker and a click-chemistry reagent enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-bearing molecules.
- Contains a propargyl (alkyne) group for CuAAC reactions.
- Designed for antibody conjugation and general bioconjugation.
- Molecular formula C10H11NO4; molecular weight 209.20 g/mol.
- High purity: 97.0%.
- Stored at -20°C in pure form; available in small pack sizes for research use.
Medchemexpress LLC Propargyl-PEG2-bromi 250mg
Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Propargyl-PEG2-bromide is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups