Hydrobromides
Selleck Chemical LLC Arecoline HBr S2614-50mg
Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist
Medchemexpress LLC CCT031374 hydrobromide | 1219184-91-4 | MFCD06737234 | 98.1% | 434.33 g·mol⁻¹ | C23H20BrN3O | 5 MG
CCT031374 hydrobromide is the hydrobromide salt of a small-molecule β-catenin/TCF signaling inhibitor supplied for research use only. It is provided as an off-white to light yellow solid with high chemical purity and is intended for pathway inhibition, cell signaling assays, and preclinical studies.
- β-catenin/TCF signaling inhibitor
- High purity (98.1%)
- Molecular weight 434.33 g·mol⁻¹
- Off-white to light yellow solid form
- Available in milligram-scale packages for research use
- Intended for in vitro and in vivo research applications
Medchemexpress LLC Pifithrin-β hydrobromide | 511296-88-1 | 100.0% | 349.29 | 50 MG
Pifithrin-β hydrobromide, also known as PFT β hydrobromide, is a potent p53 inhibitor with an IC50 of 23 μM. It is related to Pifithrin-α, a lead compound for cancer and neurodegenerative disease therapy, which rapidly converts to Pifithrin-β, its N-acetyl derivative. Pretreatment with 1 and 10 μM pifithrin-β has shown neuroprotective effects.
- Potent p53 inhibitor
- Exerts neuroprotective effects
- Used in cancer and neurodegenerative disease research
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
eMolecules Synthonix 3-Bromopiperidine-2 6-dione 250mg 534611341 B41113 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2
Synthonix 3-Bromopiperidine-2 6-dione 250mg 534611341 B41113 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2
TARGETMOL CHEMICALS INC CCT 031374 HYDROBROMIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CCT 031374 hydrobromide is a TCF/(beta)-catenin inhibitor with antitumor activities. purity: 98%
Medchemexpress LLC Fatostatin hydrobromide (125B11 hydrobromide) | 298197-04-3 | 99.5% | C18H19BrN2S | 1 G
Fatostatin hydrobromide (125B11 hydrobromide) | 298197-04-3 | 99.5% | C18H19BrN2S | 1 G
Medchemexpress LLC SCH-202676 hydrobromide | 265980-25-4 | 96.81% | 348.26 | 1 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It exhibits antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors (GPCRs)
- Allosteric modulator of adenosine receptor (AR)
- Antiviral activity
- Inhibits 3CLpro in a time-dependent manner
- IC50 value of 0.655 μM against 3CLpro
Medchemexpress LLC Nan-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 200 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist that selectively targets the 5-HT1A receptor. This compound is intended for research use only. In vivo studies demonstrate its ability to reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Selective antagonist of 5-HT1A receptor
- Antagonist of 5-HT1 receptor
- Suitable for research applications
Medchemexpress LLC Arecaidine hydrobromide | 6013-57-6 | MFCD01692013 | 98.0% | 222.08 g/mol | C7H12BrNO2 | 10 MG
Arecaidine hydrobromide is the hydrobromide salt of arecaidine, a pyridine alkaloid that acts as a GABA uptake inhibitor. It is supplied as a research-grade reagent, typically with a reported purity of 98.0%, and is used in studies of GABA transport and related membrane transporter pathways.
- Suitable for research use only.
- Reported purity of 98.0% by supplier specification.
- Molecular formula C7H12BrNO2 and molecular weight 222.08 g/mol.
- Identified by CAS number 6013-57-6 for unambiguous substance lookup.
- Available in small research packs such as 10 mg for laboratory testing and screening.