Hydrobromides
Medchemexpress LLC Vortioxetine (hydrobromide) | 960203-27-4 | C18H23BrN2S | 1 G
Vortioxetine hydrobromide (Lu AA 21004) is a multimodal serotonergic agent that acts as an antagonist of 5-HT3A (Ki: 3.7 nM) and 5-HT7 (Ki: 19 nM) receptors. It also inhibits the 5-hydroxytryptamine transporter (SERT) with a Ki of 1.6 nM. Furthermore, it functions as a 5-HT1A agonist (Ki: 15 nM) and a partial 5-HT1B agonist (Ki: 33 nM), exhibiting potent inhibition of SERT.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- Acts as a 5-HT1A agonist
- Functions as a partial 5-HT1B agonist
- High purity of 99.87%
- Light yellow to yellow solid appearance
Medchemexpress LLC L-2,4-diaminobutyric acid hydrobromide | 73143-97-2 | MFCD07368664 | 98.0% | 199.05 g/mol | C4H11BrN2O2 | 500 MG
L-2,4-diaminobutyric acid hydrobromide (L-DABA hydrobromide) is a research chemical described as a weak GABA transaminase inhibitor (IC50 > 500 μM) and reported to exhibit antitumor activity in vitro and in vivo. It is supplied as the hydrobromide salt, CAS 73143-97-2, with molecular weight 199.05 g/mol and reported purity 98.0%.
- High purity: 98.0%.
- Reported activity: weak GABA transaminase inhibitor (IC50 > 500 μM).
- Demonstrated antitumor activity in vitro and in vivo.
- Provided as hydrobromide salt for research use.
- Available in 500 mg pack size.
Medchemexpress LLC Arecoline hydrobromide | 300-08-3 | 99.95% | 500 MG
Arecoline hydrobromide is a naturally occurring, brain-penetrant, and orally active psychoactive alkaloid. It functions as a partial agonist for both nicotinic and muscarinic acetylcholine receptors, influencing various neurological processes. This compound has been noted for its ability to induce stimulation, alertness, anxiolysis, and anti-parasitic effects, though it can also cause oxidative stress.
- Naturally occurring psychoactive alkaloid
- Brain-penetrant and orally active
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors
- Can induce stimulation, alertness, anxiolysis, and anti-parasitic effects
- Induces reactive oxygen species and cell cycle arrest in HaCaT cells
- Alleviates anxiety and depression in CFA-induced mice
eMolecules 62595-74-8 | 3-bromopiperidine-2,6-dione | Pharmablock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 250g | 812209008
3-bromopiperidine-2,6-dione | Pharmablock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 250g | 812209008
eMolecules 62595-74-8 | 3-Bromopiperidine-2,6-dione | Synthonix | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 25g | 831793877
3-Bromopiperidine-2,6-dione | Synthonix | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 25g | 831793877
Medchemexpress LLC SCH-202676 hydrobromide | 265980-25-4 | 96.81% | 348.26 | 100 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It exhibits antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors and adenosine receptor.
- Exhibits antiviral activity.
- Inhibits 3CLpro in a time-dependent manner.
- IC50 value of 0.655 μM.
Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 500 MG
Halofuginone hydrobromide is a Febrifugine derivative and a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. It is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibiting TGF-β activity. It also acts as a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Competitive prolyl-tRNA synthetase inhibitor (Ki of 18.3 nM).
- Specific inhibitor of type-I collagen synthesis.
- Attenuates osteoarthritis (OA) by inhibition of TGF-β activity.
- Potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Has anti-malaria, anti-inflammatory, anti-cancer, and anti-fibrosis effects.
Medchemexpress LLC BC-11 hydrobromide | 443776-49-6 | 99.0% | 290.97 | 25 MG
BC-11 hydrobromide is a selective TMPRSS2 inhibitor and a selective urokinase (uPA) inhibitor. It demonstrates cytotoxicity against triple-negative MDA-MB231 breast cancer cells.
- Selective TMPRSS2 inhibitor
- Selective urokinase (uPA) inhibitor
- Cytotoxic to triple-negative MDA-MB231 breast cancer cells
- Used in research on viral infections and cancer
Cayman Chemical FenoterolhydrobromIde 10mg
An analytical reference standard categorized as a β2-adrenergic receptor agonist; has been used as a performance-enhancing drug in sports doping and is banned by WADA; intended for research and forensic applications
Medchemexpress LLC Oxidopamine hydrobromide | 636-00-0 | 99.42% | 100 MG
Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. It is a widely used neurotoxin that selectively destroys dopaminergic neurons. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrobromide can be used for the research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Antagonist of the neurotransmitter dopamine.
- Widely used neurotoxin.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation.
- Leads to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Used for research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
TARGETMOL CHEMICALS INC Clobenpropit dihydrobromide
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07) Purity 99.48%
Apexbio Technology LLC Scopolamine hydrobromide 114-49-8 500mg
Scopolamine hydrobromide (114-49-8) is a small-molecule antagonist targeting muscarinic acetylcholine receptors and serotonin 5-HT3 receptors It is designed to reversibly block these receptors thereby modulating cholinergic and serotonergic signaling pathways Scopolamine hydrobromide exerts its biological activity primarily through reversible antagonism of muscarinic receptors and inhibition of serotonin 5-HT3 receptor responses In receptor binding studies Scopolamine hydrobromide demonstrates antagonistic activity with reported IC50 values generally ranging from nanomolar to micromolar concentrations depending on the receptor subtype and experimental conditions Based on these pharmacological properties Scopolamine hydrobromide holds research potential in studies of neurotransmission cholinergic signaling gastrointestinal motility assays cognitive impairment models and emesis reflex investigations