Hydrochlorides
Medchemexpress LLC GW405833 hydrochloride | 1202865-22-2 | 99.6% | 483.82 | 1 MG
GW405833 hydrochloride | 1202865-22-2 | 99.6% | 483.82 | 1 MG
Medchemexpress LLC Kevetrin hydrochloride | 66592-89-0 | 98.0% | 179.67 | 1 ML
Kevetrin hydrochloride is a potent activator of p53, inducing apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. It exhibits preferential cytotoxic activity against blast cells.
- Potent activator of p53.
- Induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells.
- Exhibits preferential cytotoxic activity against blast cells.
Medchemexpress LLC Co 101244 (hydrochloride) | 193356-17-1 | 99.9% | 377.90 g/mol | C21H28ClNO3 | 25 MG
Co 101244 hydrochloride is the hydrochloride salt of a selective NR2B-containing NMDA receptor antagonist used in pharmacology and neuroscience research. It is supplied as a solid with high purity and is accompanied by supporting documentation for safe handling and experimental use.
- High purity: 99.9%.
- Molecular weight 377.90 g/mol.
- Chemical formula C21H28ClNO3.
- Appearance solid, light yellow to yellow.
- Storage recommendations: store sealed and away from moisture; in solvent, -80°C for up to 6 months, -20°C for up to 1 month.
- Includes datasheet and safety data sheet for handling and hazard information.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC GW405833 hydrochloride | 1202865-22-2 | 99.59% | 483.82 | 1 ML
GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. It has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. It also acts as a non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor dependent mechanism. It can significantly inhibit the production of cAMP stimulated by Forskolin and inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF).
- Potent, selective cannabinoid receptor 2 (CB2) agonist
- EC50 and Ki values for CB2: 0.65 nM and 3.92 nM respectively
- EC50 and Ki values for CB1: 16.1 μM and 4772 nM respectively
- Non-competitive CB1 antagonist
- Inhibits cAMP production stimulated by Forskolin
- Inhibits glycolysis by down-regulating HIF-1α
Medchemexpress LLC SKF89976A hydrochloride | 85375-15-1 | 98.7% | 371.90 | C22H26ClNO2 | 25 MG
Hydrochloride salt used as a selective inhibitor of the GABA transporter GAT-1 for in vitro research. It exhibits IC50 values of 0.28 μM (GAT-1), 137.34 μM (GAT-2), and 202.8 μM (GAT-3) in CHO cells, and is supplied as a solid and as a 10 mM solution in DMSO.
![Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242004.png-250.jpg)
Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG
VU 0255035 is a selective, competitive antagonist of the M1 muscarinic acetylcholine receptor used in preclinical research on central nervous system disorders. The compound (CAS 1135243-19-4) has molecular formula C18H20N6O3S2 and is supplied as a high-purity research-grade material for in vitro and in vivo pharmacology.
- Selective M1 receptor antagonism for pharmacological and mechanistic studies.
- High chemical purity suitable for analytical and biological assays.
- Available in multiple small-quantity formats for flexibility in dosing and screening.
- Suitable for both in vitro and in vivo experimental applications.
- Stable when stored under recommended conditions for research use.
Medchemexpress LLC VU0364770 hydrochloride | 1414842-70-8 | 99.7% | 269.13 g/mol | C12H10Cl2N2O | 1 ML
VU0364770 hydrochloride is a selective and potent positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), supplied as a ready-to-use 10 mM solution in DMSO for laboratory research. The compound has reported physicochemical identifiers and storage recommendations for reliable experimental use.
Medchemexpress LLC Mln120b dihydrochloride | 1782573-78-7 | 99.7% | 439.72 g·mol⁻¹ | C19H17Cl3N4O2 | 10 MG
MLN120B dihydrochloride is the dihydrochloride salt of MLN120B, a potent, ATP-competitive inhibitor of IKKβ used as a reference compound in NF-κB pathway and inflammatory disease research. It demonstrates an IC50 of approximately 60 nM against IKKβ and has been applied in biochemical, cellular, and in vivo studies. Supplied as a high-purity solid for laboratory research use only.
- Potent ATP-competitive inhibitor of IKKβ (IC50 ≈ 60 nM).
- Used in cellular and in vivo studies to inhibit multiple myeloma growth.
- High purity (≈99.7%).
- Suitable for biochemical and cellular assays.
- Available in small vials (5 mg, 10 mg, 25 mg, 50 mg).
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Benzamide, N-(aminoiminomethyl)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl) hydrochloride | 211813-86-4 | MFCD31560490 | 99.5% | 356.83 | C14H17ClN4O3S | 10 MG
Eniporide hydrochloride is a small-molecule Na+/H+ exchanger inhibitor provided as the hydrochloride salt for use in biochemical and pharmacological research. It has been used in preclinical studies of cardiac ischemia/reperfusion and cellular ion regulation. The compound is supplied as a high-purity solid with recommended cold storage to preserve stability.
- Potent Na+/H+ exchanger inhibitor
- Hydrochloride salt form for improved stability
- High purity (99.5%) suitable for research applications
- Solid form, convenient for storage and handling
- Recommended storage: 4°C; in solvent -80°C (6 months) or -20°C (1 month)
- Suitable for studies of ion transport and cardiac models
Medchemexpress LLC Aldoxorubicin hydrochloride | 480998-12-7 | 98.0% | 787.21 g/mol | C37H43ClN4O13 | 5 MG
Aldoxorubicin hydrochloride is an albumin-binding proagent of doxorubicin that functions as a DNA topoisomerase II inhibitor and exhibits acid-sensitive release properties. It is supplied as a high-purity research reagent for preclinical laboratory use.
- Albumin-binding proagent of doxorubicin
- Acid-sensitive release of active doxorubicin
- Acts as a DNA topoisomerase II inhibitor
- Available as small-mass research packs (e.g., 5 mg)
- High reported purity (around 98%)
Medchemexpress LLC Benzenepropanamine, gamma-(2-methoxyphenoxy)-N-methyl-, hydrochloride | 57754-86-6 | 99.9% | 307.82 | C17H22ClNO2 | 10 MG
Nisoxetine hydrochloride is a research-grade small molecule that potently and selectively inhibits the noradrenaline (norepinephrine) transporter (NET) and can block voltage-gated sodium channels. It is supplied as a solid powder for use in transporter pharmacology, neurotransmitter uptake assays, and sodium channel studies.
- Potent, selective noradrenaline transporter (NET) inhibitor (reported Kd ≈ 0.76 nM).
- Acts as an antidepressant-class compound and local anesthetic via sodium channel blockade.
- High purity suitable for biochemical assays and pharmacology studies.
- Available in small-scale powder sizes and DMSO solution formats for ready use.
- Stable when stored under recommended conditions (powder and in solvent).
Apexbio Technology LLC Dapoxetine HCl 129938-20-1 25mg
Dapoxetine hydrochloride (CAS 129938-20-1) is a short-acting selective serotonin reuptake inhibitor (SSRI) It exerts its pharmacological effect by inhibiting the reuptake of serotonin (5-HT) at the presynaptic membrane thereby increasing serotonin activity in the synaptic cleft This modulation of serotonergic neurotransmission has been shown to delay ejaculation latency making dapoxetine hydrochloride an established model compound for investigating serotonergic regulation of ejaculatory control It is widely used in research on the neurobiology and therapeutic approaches to premature ejaculation and related disorders
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 10mM (in 1mL DMSO)
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
Medchemexpress LLC Cp-409092 hydrochloride | 225240-86-8 | 99.8% | 333.81 g/mol | C17H20ClN3O2 | 25 MG
CP-409092 hydrochloride is a research chemical that functions as a partial agonist of the GABAA receptor and has reported anxiolytic activity. Supplied as the hydrochloride salt, it is provided as a high-purity solid for in vitro and in vivo pharmacology studies.
- Acts as a partial agonist of the GABAA receptor.
- Demonstrates reported anti-anxiety (anxiolytic) activity in pharmacological assays.
- High purity (≈99.8%) with white to off-white solid appearance.
- Soluble in water and DMSO with ultrasonic assistance for stock preparation.
- Documented with COA, SDS, and data sheet for research handling.
Medchemexpress LLC Cyclopentanecarboxylic acid, 1-(4-nitrophenyl)-, 2-(diethylamino)ethyl ester, hydrochloride | 98636-73-8 | MFCD00673872 | 99.6% | 370.87 g/mol | C18H27ClN2O4 | 25 MG
Nitrocaramiphen hydrochloride is a selective M1 muscarinic receptor antagonist supplied as the hydrochloride salt for research use. It inhibits muscarine-induced hyperpolarization in muscle fibers and is provided as a white to off-white solid suitable for biochemical and pharmacological studies.
- Selective M1 receptor antagonist (Ki: 5.5 nM).
- High purity: 99.6% (manufacturer COA).
- White to off-white solid, molecular formula C18H27ClN2O4.
- Molecular weight 370.87 g/mol.
- Available in small milligram quantities for research use.
- Store sealed away from moisture; in solvent: -80°C (6 months), -20°C (1 month).