Hydrochlorides
Medchemexpress LLC Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 5 MG
Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 5 MG
Medchemexpress LLC VU 0240551 | 893990-34-6 | 99.7% | 342.44 | 50 MG
VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) that exhibits selectivity over NKCC1. It also acts as an inhibitor of hERG and L-type Ca2+ channels. This compound reduces GABA-induced hyperpolarization of P cells, leading to a positive shift in the P cell GABA reversal potential and an enhancement of P cell synaptic transmission. It is intended for research use only.
- Potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM)
- Selective against NKCC1
- Inhibits hERG and L-type Ca2+ channels
- Attenuates GABA-induced hyperpolarization of P cells
- Produces a positive shift in the P cell GABA reversal potential
- Enhances P cell synaptic transmission
Medchemexpress LLC 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrochloride | 62717-42-4 | MFCD00069248 | 99.5% | 291.77 g/mol | C16H18ClNO2 | 500MG
SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor used as a research reagent to study D1-mediated signaling. It is supplied as a solid (also available as a 10 mM solution in DMSO) with analytical-grade purity and intended for research use only.
- CAS number 62717-42-4.
- Chemical formula C16H18ClNO2.
- Molecular weight 291.77 g/mol.
- D1 receptor IC50 ~110 nM.
- Purity approximately 99.5%.
- Available as solid quantities including 500 mg and larger sizes.
- Provided for research use only; not for human or clinical use.
Selleck Chemical LLC Duloxetine HCl S2084-10mg
Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4 6 nM used for treatment of major depressive disorder and generalized anxiety disorder (GAD)
Medchemexpress LLC TG 100572 hydrochloride | 867331-64-4 | 98.8% | 512.43 g/mol | C26H27Cl2N5O2 | 25 MG
TG 100572 Hydrochloride is the hydrochloride salt of TG 100572, a multi-targeted kinase inhibitor that potently inhibits several receptor tyrosine kinases and Src family kinases. Supplied as a pink-red solid for research use, the material is provided at high purity with specified storage recommendations to maintain stability and activity.
- Multi-targeted kinase inhibitor activity.
- Inhibits receptor tyrosine kinases and Src family kinases.
- High purity for research applications.
- Pink to red solid appearance.
- Stable when stored sealed and protected from moisture.
- Available as solid quantities and as a DMSO solution.
![eMolecules 1022094-03-6 | (S)-3-Methylmorpholine hydrochloride | Combi-Blocks | MFCD18382512 | 137.610 | C5H12ClNO | 95.000 | Cl.C[C@H]1COCCN1 | 1g | 415498130](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1756841.jpg-250.jpg)
eMolecules 1022094-03-6 | (S)-3-Methylmorpholine hydrochloride | Combi-Blocks | MFCD18382512 | 137.610 | C5H12ClNO | 95.000 | Cl.C[C@H]1COCCN1 | 1g | 415498130
(S)-3-Methylmorpholine hydrochloride | Combi-Blocks | 1022094-03-6 | MFCD18382512 | 137.610 | C5H12ClNO | 95.000 | Cl.C[C@H]1COCCN1 | 1g | 415498130
Medchemexpress LLC O-Ethylhydroxylamine-d5 hydrochloride | 118087-07-3 | 99.7% | 102.57 | 5 MG
O-Ethylhydroxylamine-d5 (hydrochloride) is a deuterium-labeled form of O-Ethylhydroxylamine hydrochloride. It serves as a valuable tool for research, functioning as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules is a growing area of study, primarily utilized for quantitative analysis during the drug development process. Deuteration specifically holds promise for modifying the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
- Used as a tracer for quantitative analysis.
- Functions as an internal standard in analytical techniques.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Contains stable heavy isotopes for research in drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
eMolecules 4781-83-3 | 2-Iminothiolane HCl salt | Broadpharm | MFCD00216010 | 101.170 | C4H7NS | 97.000 | N=C1CCCS1 | 500mg | 686681063
2-Iminothiolane HCl salt | Broadpharm | 4781-83-3 | MFCD00216010 | 101.170 | C4H7NS | 97.000 | N=C1CCCS1 | 500mg | 686681063
Medchemexpress LLC VU-1545 | 890764-63-3 | 99.0% | 402.38 | 100 MG
VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9.6 nM.
- Promotes AKT activation at concentrations of 0.1 and 1.0 μM.
- Neuroprotective in a mouse model of Huntington's disease.
- For research use only, not for sale to patients.
![Medchemexpress LLC N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 g/mol | C18H20N6O3S2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244005.png-250.jpg)
Medchemexpress LLC N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 g/mol | C18H20N6O3S2 | 25 MG
VU 0255035 is a selective, competitive antagonist of the M1 muscarinic acetylcholine receptor used as a research compound for central nervous system studies, including seizure models and investigations of neuronal excitability. It is supplied with high purity and is available in solid and solution formats for in vitro and in vivo experiments.
- Selective M1 antagonist with reported nanomolar activity.
- Brain-penetrant compound suitable for in vivo CNS studies.
- High supplied purity (≈99.8%).
- Molecular weight 432.52 g/mol (C18H20N6O3S2).
- Available in multiple pack sizes and DMSO solution formats for easy dosing.
Medchemexpress LLC N-(1,3-diphenylpyrazol-5-yl)-4-nitrobenzamide | 890764-36-0 | MFCD12546140 | 99.6% | 384.39 g/mol | C22H16N4O3 | 5 MG
VU-29 is a research small molecule that acts as a positive allosteric modulator of the metabotropic glutamate 5 (mGlu5) receptor. It potentiates mGlu5 signaling with high potency and selectivity, and is supplied for laboratory research in solid or solution formats.
- Positive allosteric modulator of mGlu5 with high potency (EC50 ≈ 9 nM).
- Selective for mGlu5 versus other metabotropic glutamate receptors.
- Reported high purity suitable for biochemical and cellular assays.
- Available as small solid quantities or as 10 mM solutions in DMSO for convenience.
- Chemical formula C22H16N4O3; molecular weight 384.39 g/mol.
Medchemexpress LLC UK-78282 hydrochloride | 136647-02-4 | 99.82% | 466.05 | 5 MG
UK-78282 is a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. It effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel, overlapping the site of action of verapamil.
- IC50 & Target: 200 nM (Kv1.3)
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | MFCD00673899 | 100.0% | 390.87 g/mol | C19H26ClF3N2O | 1 ML
ZT 52656A hydrochloride is a selective kappa opioid receptor agonist used in research to prevent or alleviate ocular pain. The compound is provided as a solid or as a ready-to-use 10 mM solution in DMSO, with high reported purity and manufacturer guidance for storage to maintain stability.
- Selective kappa opioid receptor agonist suitable for ocular pain studies.
- Available as solid or pre-dissolved 10 mM solution in DMSO for convenience.
- High reported purity for consistent experimental results.
- Multiple pack sizes accommodate small- and large-scale experiments.
- Defined storage recommendations help preserve compound stability in solid and solution forms.
Medchemexpress LLC Vu 0255035 | 1135243-19-4 | 99.8% | 432.52 | C18H20N6O3S2 | 5 MG
VU 0255035 is a selective M1 muscarinic receptor antagonist used as a research tool to probe M1-mediated signaling and synaptic responses in neuronal preparations. It is supplied as a solid with high purity and is characterized by its molecular formula and weight; handle under recommended storage conditions for best stability.
- Selective M1 muscarinic receptor antagonist with demonstrated neuronal activity.
- High purity: 99.8%.
- Molecular weight 432.52; formula C18H20N6O3S2.
- Available in small research quantities, such as 5 mg.
- Supplied as a solid; store at 4°C and protect from light (in solvent: -80°C for long-term storage).
- Suitable as a pharmacological probe for electrophysiology and signaling assays.
TARGETMOL CHEMICALS INC Anabasine 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. (±) Anabasine is a muscle relaxant that can be used for muscle relaxation during surgery.