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Filtered Search Results
eMolecules Broadpharm / 2-Iminothiolane HCl salt / 500mg / 686681063 / BP-27870 / 95.000 / 4781-83-3 / MFCD00216010 / 101.170 / C4H7NS
Broadpharm / 2-Iminothiolane HCl salt / 500mg / 686681063 / BP-27870 / 95.000 / 4781-83-3 / MFCD00216010 / 101.170 / C4H7NS
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Medchemexpress LLC Erlotinib (hydrochloride) | 183319-69-9 | 99.9% | 1 G
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Erlotinib hydrochloride is the hydrochloride salt of erlotinib, a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase intended for research use. It inhibits purified EGFR kinase with an IC50 of 2 nM and contains an alkyne group enabling copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Inhibits EGFR kinase; IC50 = 2 nM.
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High purity (99.94%) suitable for analytical and research applications.
- Molecular formula C22H24ClN3O4, molecular weight 429.90.
- Solid, melting point 223-225 °C; recommended storage 4 °C (sealed).
- Typically supplied as a 1 g research pack.
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Medchemexpress LLC 1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione | 1160247-92-6 | 99.9% | 50 MG
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VU 0238429 is a small-molecule research compound that acts as a positive allosteric modulator of the muscarinic acetylcholine receptor subtype 5 (mAChR5, M5). It potentiates M5 with an EC50 of 1.16 μM, shows >30-fold selectivity versus M1 and M3, and is supplied as solid or as a 10 mM solution in DMSO at high purity for laboratory research.
- Positive allosteric modulator of mAChR5 with EC50 1.16 μM.
- Greater than 30-fold selectivity versus M1 and M3; no M2 or M4 potentiation.
- Available as solid (multiple sizes) and 10 mM solution in DMSO.
- High purity (listed around 99.9%).
- Intended for laboratory research use only; not for human use.
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Medchemexpress LLC Benzamide, N-(aminoiminomethyl)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl) hydrochloride | 211813-86-4 | MFCD31560490 | 99.5% | 356.83 | C14H17ClN4O3S | 10 MG
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Eniporide hydrochloride is a small-molecule Na+/H+ exchanger inhibitor provided as the hydrochloride salt for use in biochemical and pharmacological research. It has been used in preclinical studies of cardiac ischemia/reperfusion and cellular ion regulation. The compound is supplied as a high-purity solid with recommended cold storage to preserve stability.
- Potent Na+/H+ exchanger inhibitor
- Hydrochloride salt form for improved stability
- High purity (99.5%) suitable for research applications
- Solid form, convenient for storage and handling
- Recommended storage: 4°C; in solvent -80°C (6 months) or -20°C (1 month)
- Suitable for studies of ion transport and cardiac models
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Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 | C4H8ClNS | 10 MG
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2-Iminothiolane hydrochloride is a thiolating reagent used to introduce sulfhydryl (-SH) groups into primary amines of proteins, peptides, and oligosaccharides. It reacts under near-physiological conditions to expose free thiols for subsequent conjugation, crosslinking, or labeling in bioconjugation workflows.
- Reacts with primary amines at pH 7-10 to generate free thiols.
- Forms an amidine linkage that tethers the thiol to the substrate.
- Enables protein and peptide modification for bioconjugation.
- Suitable for glycan labeling and oligosaccharide modification.
- High purity for reproducible experimental results (>99.9%).
- Solid, white to off-white material that is easy to handle and weigh.
- Available in small research-scale pack sizes for laboratory use.
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Medchemexpress LLC TG 100572 hydrochloride | 867331-64-4 | 98.8% | 512.43 g/mol | C26H27Cl2N5O2 | 25 MG
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TG 100572 Hydrochloride is the hydrochloride salt of TG 100572, a multi-targeted kinase inhibitor that potently inhibits several receptor tyrosine kinases and Src family kinases. Supplied as a pink-red solid for research use, the material is provided at high purity with specified storage recommendations to maintain stability and activity.
- Multi-targeted kinase inhibitor activity.
- Inhibits receptor tyrosine kinases and Src family kinases.
- High purity for research applications.
- Pink to red solid appearance.
- Stable when stored sealed and protected from moisture.
- Available as solid quantities and as a DMSO solution.
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Medchemexpress LLC 1H-indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl] hydrochloride | 108050-82-4 | 99.0% | 382.93 g/mol | C23H27ClN2O | 100 MG
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Roxindole hydrochloride is the hydrochloride salt of roxindole (EMD 38362), a research tool compound investigated as a dopamine autoreceptor (D2-like) agonist and a 5-HT1A agonist that also inhibits serotonin uptake. It is used in vitro and in vivo to study dopaminergic and serotonergic signaling and to model psychiatric disorder pharmacology.
- High purity (99.0%) suitable for analytical and research use.
- Molecular weight 382.93 g/mol for accurate dosing calculations.
- Hydrochloride salt form to improve solubility in polar solvents.
- Appropriate for in vitro and in vivo pharmacology studies.
- Provided in milligram quantities to support small-scale experiments.
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Medchemexpress LLC BPR1J-097 hydrochloride | 00-00-0 | 99.2% | C27H29ClN6O3S | 10MG
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BPR1J-097 hydrochloride is a small-molecule FLT3 kinase inhibitor with nanomolar potency for use in biochemical and cellular research. Supplied as the hydrochloride salt with high chemical purity, it is intended for pharmacological profiling and in vitro assay applications where selective FLT3 inhibition is required.
- Potent FLT3 inhibition (IC50 ~11 nM).
- High chemical purity (99.2%).
- Hydrochloride salt form for improved solubility.
- Characterized by molecular formula C27H29ClN6O3S and MW 553.08.
- Intended for research use in biochemical and cellular assays.
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TARGETMOL CHEMICALS INC RS-127445 25MG
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502693733 RS-127445 25MG
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Medchemexpress LLC SB-399885 hydrochloride | 402713-81-9 | 98.3% | 482.81 g/mol | C18H22Cl3N3O4S | 100 MG
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SB-399885 hydrochloride is a research-grade small molecule that functions as a selective 5-HT6 receptor antagonist for laboratory pharmacology and neuroscience studies. It is supplied as a solid reagent and should be handled and stored according to standard laboratory safety practices.
- Acts as a selective 5-HT6 receptor antagonist
- Suitable for in vitro and in vivo pharmacology studies
- Supplied as a solid with reported purity of 98.3%
- Molecular weight 482.81 g/mol; CAS 402713-81-9
- Available in multiple pack sizes for dose-ranging experiments
- For research use only; not for human or clinical use
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Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 5 mg substrate per tablet | 615-28-1 | MFCD00012966 | 50TAB
o-Phenylenediamine dihydrochloride tablet, 5 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 50TAB
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Medchemexpress LLC (R)-DRF053 dihydrochloride | 1241675-76-2 | >98.0% | 490.43 g/mol | C23H29Cl2N7O | 1 MG
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(R)-DRF053 dihydrochloride is the dihydrochloride salt of a small-molecule inhibitor that targets casein kinase 1 and several cyclin-dependent kinases. It is supplied in small research quantities for use as a biochemical and cellular probe to study kinase signaling and amyloid-beta production.
- Potent inhibition of CK1, CDK1/cyclin B, and CDK5/p25 with reported IC50s of 14 nM, 220 nM, and 80 nM respectively.
- Dihydrochloride salt form suitable for biochemical and cellular assays.
- High purity, typically >98% by HPLC.
- Molecular weight approximately 490.43 g/mol and chemical formula C23H29Cl2N7O.
- Available in small research quantities for preclinical use (for example, 1 mg packages).
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Medchemexpress LLC TC-A 2317 hydrochloride | 1245907-03-2 | MFCD19690936 | 99.6% | 392.93 g/mol | C19H29ClN6O | 10 MG
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TC-A 2317 hydrochloride is the hydrochloride salt of TC-A 2317, a potent, orally active Aurora A kinase inhibitor characterized for cellular activity and antitumor effects. It is supplied as a high-purity research reagent suitable for in vitro and in vivo pharmacology studies.
- Potent Aurora A kinase inhibitor (Ki = 1.2 nM).
- Selective over Aurora B kinase (Ki = 101 nM) and many other kinases.
- Hydrochloride salt form for improved stability and solubility.
- High purity suitable for research (≈99.6%).
- Available in small milligram quantities for preclinical studies.
- Molecular weight 392.93 g/mol; molecular formula C19H29ClN6O.
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Medchemexpress LLC Ipn60090 dihydrochloride | 2102101-72-2 | 99.7% | 605.44 g/mol | C24H29Cl2F3N8O3 | 1 ML
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IPN60090 dihydrochloride is a potent, selective small-molecule inhibitor of glutaminase 1 (GLS1), provided as a dihydrochloride salt for preclinical research. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid samples, with reported high purity and documented in vitro and in vivo activity supporting use in solid tumor studies.
- Highly selective GLS1 inhibitor with reported IC50 = 31 nM.
- Inhibits A549 cell proliferation (IC50 = 26 nM).
- Available as 10 mM solution in DMSO (1 mL) or multiple solid sizes for experimental flexibility.
- High purity suitable for biochemical and cell-based assays.
- Documented pharmacokinetic and efficacy data in preclinical models.
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Apexbio Technology LLC Tirofiban 144494-65-5 5mg
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Tirofiban is a selective non-peptide antagonist targeting platelet glycoprotein (GP) IIb/IIIa receptors a heterodimeric complex abundantly expressed on platelet surfaces responsible for mediating fibrinogen binding and platelet aggregation It acts through competitive inhibition of fibrinogen binding at GP IIb/IIIa sites thereby suppressing platelet cross-linking and aggregation induced by agonists like ADP In vitro studies demonstrate that Tirofiban inhibits ADP-induced platelet aggregation with an IC50 value of approximately 9 nM showing significantly lower affinity for integrin v 3 (vitronectin receptor) Tirofiban is frequently applied in biomedical research investigating platelet aggregation mechanisms and thrombotic events
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