Hydrochlorides
![Medchemexpress LLC Cyclopentanecarboxamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[2-(2,3,5,6-tetrafluorophenoxy)acetyl]bu | 2097865-47-7 | 97.2% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Cyclopentanecarboxamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[2-(2,3,5,6-tetrafluorophenoxy)acetyl]bu | 2097865-47-7 | 97.2% | 25 MG
Kgp-IN-1 hydrochloride is an arginine-specific gingipain (Rgp) inhibitor, identified as compound 13-R from patent WO2017201322A1. This product is intended for research use only.
- Arginine-specific gingipain (Rgp) inhibitor
- Targets cathepsin
- Pathway: metabolic enzyme/protease
- White to off-white solid
- Store at 4°C, sealed, away from moisture
Medchemexpress LLC RS-102221 hydrochloride | 187397-18-8 | 98.0% | 649.08 | C27H32ClF3N4O7S | 10 MG
RS-102221 hydrochloride is the hydrochloride salt of a selective 5-HT2C receptor antagonist used in pharmacology and neuroscience research. Supplied for preclinical and in vitro studies, it provides selective blockade of 5-HT2C receptors to support receptor pharmacology, behavioral, and signaling experiments.
- Selective 5-HT2C receptor antagonist (high affinity).
- High purity (~98.0%).
- Molecular weight 649.08 g/mol.
- CAS number 187397-18-8 for unequivocal identification.
- Available in small preclinical quantities (for example, 10 mg).
- Product page includes datasheet and safety data sheet.
Medchemexpress LLC A-674563 hydrochloride | 2070009-66-2 | 99.6% | 394.90 | 5 MG
A-674563 hydrochloride is a potent and selective Akt1 inhibitor with a Ki of 11 nM. This product is suitable for laboratory research and includes the following features:
- Potent and selective Akt1 inhibitor
- Light yellow to brown solid appearance
- Soluble in water and DMSO
- Stored under nitrogen, away from moisture
Medchemexpress LLC VU0360172 hydrochloride | 1309976-62-2 | 98.9% | 330.78 g/mol | C18H16ClFN2O | 25 MG
VU0360172 hydrochloride is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5) used as a research tool in pharmacology and neuroscience. Supplied as the hydrochloride salt, the compound is intended for in vitro assays and preclinical in vivo studies and is provided with high purity and defined storage recommendations.
- Potent mGlu5 positive allosteric modulator (EC50 = 16 nM).
- Selective pharmacological tool for mGlu5 receptor studies.
- High purity suitable for biochemical and preclinical assays.
- Multiple milligram pack sizes available for laboratory experiments.
- Recommended storage conditions provided to maintain stability.
Medchemexpress LLC Dcpt1061 hydrochloride | 2289726-31-2 | 99.9% | 375.72 | 1 ML
DCPT1061 hydrochloride exhibits a potent inhibitory effect on PRMT1, PRMT6, and PRMT8 in vitro, with minimal inhibitory effects on epigenetic enzymes such as PRMT3, PRMT4, and PRMT5. It also possesses antitumor properties.
- Solid appearance
- Color is white to off-white
- Ships at room temperature in continental US
- Store at -20°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO at 50 mg/mL (133.08 mM)
Medchemexpress LLC DCPT1061 hydrochloride | 2289726-31-2 | 99.9% | 375.72 | 5 MG
DCPT1061 hydrochloride is a compound that exhibits a strong inhibitory effect on PRMT1, PRMT6, and PRMT8 in vitro, with little inhibitory effect on epigenetic enzymes such as PRMT3, PRMT4, and PRMT5. It also demonstrates antitumor effects.
- Selective inhibition: Strongly inhibits PRMT1, PRMT6, and PRMT8.
- Minimal off-target effects: Little inhibitory effect on PRMT3, PRMT4, and PRMT5.
- Antitumor properties: Exhibits antitumor effects.
- Research use: For research use only.
Sigma Aldrich Fine Chemicals Biosciences 4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | 109-02-4 | MFCD00006175 | 100ML
4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | Purity: >=99.5% (GC) | Mol Wt: 101.15 | 109-02-4 | MFCD00006175 | 100ML
Medchemexpress LLC Ambroxol (hydrochloride) | 23828-92-4 | 99.9% | 25 MG
Ambroxol hydrochloride is an active metabolite of Bromhexine, known for its potent expectorant effects. It acts as a glucocerebrosidase (GCase) chaperone, enhancing GCase activity. It induces lung autophagy and is being researched for potential use in Parkinson's disease and neuronopathic Gaucher disease.
- Potent expectorant effects.
- Acts as a glucocerebrosidase (GCase) chaperone.
- Increases glucocerebrosidase activity.
- Induces lung autophagy.
- Potential for research in Parkinson's disease.
- Potential for research in neuronopathic Gaucher disease.
Medchemexpress LLC Ynt-185 dihydrochloride | 1804978-82-2 | 99.8% | C33H39Cl2N5O5S | 10MG
YNT-185 dihydrochloride is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist used as a research tool to probe orexin signaling and sleep disorder models. It exhibits high potency at OX2R (EC50 = 0.028 μM) and lower activity at OX1R, and is supplied as a solid or as a 10 mM DMSO stock solution for laboratory use. For research use only.
- Selective OX2R agonist with nanomolar potency (EC50 = 0.028 μM).
- Lower activity at OX1R, enabling receptor subtype studies.
- High purity for reproducible biochemical and pharmacological results.
- Available in multiple pack sizes and as a 10 mM DMSO stock solution.
- Supplied as an off-white to light-yellow solid suitable for formulation.
Medchemexpress LLC Naloxone hydrochloride (Standard) | 357-08-4 | 99.7% | 363.84 | 25 MG
Naloxone hydrochloride (Standard) | 357-08-4 | 99.7% | 363.84 | 25 MG
Medchemexpress LLC KB-0742 dihydrochloride | 2416874-75-2 | 98.8% | 360.33 | 50 MG
KB-0742 dihydrochloride is a potent, selective, and orally active inhibitor of CDK9/cyclin T1, demonstrating an IC50 of 6 nM. It exhibits over 50-fold selectivity against other CDK kinases and shows significant anti-tumor activity. This compound has been shown to reduce downstream phosphorylation of RNA Pol II at Ser2, Ser7, and Ser5, and to diminish global androgen receptor protein levels in prostate cancer cells. It also displays antiproliferative effects in various cancer cell lines, such as prostate cancer and leukemia.
- Potent and selective CDK9 inhibitor.
- Orally active with significant anti-tumor efficacy.
- Exhibits high selectivity for CDK9/cyclin T1 over other CDK kinases.
- Induces significant reduction of RNA Pol II phosphorylation.
- Demonstrates antiproliferative activity in cancer cell lines.
Medchemexpress LLC LP-533401 hydrochloride | 1040526-12-2 | 99.4% | 562.94 | 5 MG
LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1, an enzyme that regulates the production of serotonin in the gut. It is intended for research use only. Studies have shown that this compound can inhibit serotonin production in Tph1-expressing cells. When administered orally to rodents, it dose-dependently prevents and rescues osteoporosis by increasing bone formation. Pharmacokinetic studies suggest that it has negligible brain penetration.
- Negligible brain penetration after oral administration in rodents.
- Reduces 5-HT content in the gut, lungs, and blood of mice.
- Increases osteoblast numbers and inhibits the decrement in trabecular bone volume in mice.
- Can be dissolved in DMSO for in vitro studies.
- Protocols for in vivo dissolution in various solvent mixtures are available.
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | MFCD26960525 | 99.3% | 524.5 g/mol | C22H27Cl2N7O2S | 1 ML
Dasatinib hydrochloride is the hydrochloride salt of dasatinib, a potent ATP-competitive inhibitor of Src and Bcr-Abl family tyrosine kinases used in preclinical research. It is typically supplied as a pre-dissolved 10 mM solution in DMSO for in vitro assays (CAS 854001-07-3).
- Potent ATP-competitive inhibitor of Src and Bcr-Abl kinases.
- Supplied as a 10 mM solution in DMSO (1 mL).
- High purity suitable for analytical and biological research (approx. 99.3%).
- Useful for in vitro kinase inhibition and cell signaling studies.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Azepexole (hydrochloride) | 147663-20-5 | MFCD35200177 | >98.0% | 217.7 g/mol | C9H16ClN3O | 5 MG
Azepexole hydrochloride is the hydrochloride salt of azepexole (B-HT 933), a selective α2-adrenoceptor agonist used as a research reagent to study adrenergic receptor pharmacology and related physiological effects such as analgesia and antitussive responses.
- Selective α2-adrenoceptor agonist used in receptor pharmacology studies.
- Reported purity greater than 98% (HPLC).
- Molecular formula C9H16ClN3O and molecular weight 217.7 g/mol.
- Provided as a small-scale research pack suitable for laboratory experiments.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Azaphen dihydrochloride monohydrate | 63302-99-8 | 99.9% | C16H23Cl2N5O2 | 1 ML
Azaphen dihydrochloride monohydrate, also known as Pipofezine, is a potent inhibitor of serotonin reuptake. This tricyclic antidepressant (TCA) is approved in Russia for the treatment of depression.
- Potent inhibitor of serotonin reuptake
- Tricyclic antidepressant for depression treatment
- Available as a 10 mM solution in water
- High purity for reliable research applications