Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Pc biotin-PEG3-azide | 1937270-46-6 | 97.8% | 825.93 g/mol | C35H55N9O12S | 10 MG
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PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG3) biotinylated azide linker used for bioconjugation and the synthesis of antibody-drug conjugates. It contains an azide functional group for click chemistry and reacts in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Cleavable three-unit PEG linker.
- Contains an azide functional group for click chemistry.
- Suits copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- High research-grade purity.
- Available in small-scale quantities for conjugation workflows.
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Medchemexpress LLC NH2-PEG3 (PROTAC Linker 35) | 6338-55-2 | 149.19 | 25 G
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NH2-PEG3 (PROTAC Linker 35) is a polyethylene glycol (PEG) linker used in the synthesis of PROTACs such as β-NF-JQ1. This chemical is intended for research use only.
- PROTAC linker
- Polyethylene glycol linker
- Used in the synthesis of PROTAC (β-NF-JQ1)
- Purity: 99.9%
- Molecular weight: 149.19
- Formula: C6H15NO3
- Appearance: Liquid (density: 1.0773 g/cm3)
- Color: Colorless to light yellow
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Medchemexpress LLC m-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 500 MG
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m-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, where one ligand is for an E3 ubiquitin ligase and the other targets a specific protein.
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC T-Boc-aminooxy-PEG5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 50 MG
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group for reactions
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
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Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.35% | 508.56 | 50 MG
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
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Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
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Medchemexpress LLC N-(Amino-PEG5)-N-bis(PEG4-acid) | 2093152-86-2 | 99.5% | 100 MG
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N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative featuring an amino group and two terminal carboxylic acids. The amino group is reactive with carboxylic acids and activated NHS esters, while the terminal carboxylic acids can react with primary amine groups to form a stable amide bond. This compound is useful in the development of antibody drug conjugates (ADCs).
- Features an amino group and two terminal carboxylic acids.
- Amino group is reactive with carboxylic acids and activated NHS esters.
- Terminal carboxylic acids react with primary amine groups to form a stable amide bond.
- Useful in the development of antibody drug conjugates (ADCs).
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Medchemexpress LLC Pomalidomide 4'-PEG3-azide | 2271036-46-3 | 96.3% | 100 MG
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Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates a Pomalidomide-based cereblon ligand and a linker. It is used for the synthesis of iRucaparib-TP3, a highly efficient PARP1 degrader developed using the PROTAC approach. This compound is also a click chemistry reagent containing an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- E3 ligase ligand-linker conjugate
- Incorporates a Pomalidomide-based cereblon ligand
- Utilized for synthesis of iRucaparib-TP3
- Highly efficient PARP1 degrader
- Click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reactions
- Enables strain-promoted alkyne-azide cycloaddition reactions
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Medchemexpress LLC 2-(2-(2-((6-chlorohexyl)oxy)ethoxy)ethoxy)ethan-1-ol | 1355955-95-1 | MFCD32705069 | 95.0% | 268.78 g/mol | C12H25ClO4 | 250 MG
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HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a six-carbon chlorinated alkyl chain, used as a building block in PROTAC and bioconjugation chemistry. It serves as a flexible, hydrophilic spacer for attaching ligands, tags, or warheads during linker assembly and small-scale synthesis.
- Polyethylene glycol (PEG3) spacer with terminal hydroxy and six-carbon chloride.
- Designed for PROTAC linker assembly and bioconjugation.
- Flexible and hydrophilic to improve solubility and spacing between functional groups.
- Supplied in research-scale packs suitable for method development and small-scale synthesis.
- Molecular formula C12H25ClO4; molecular weight 268.78 g/mol.
- CAS number 1355955-95-1; supplier-reported purity typically 95%.
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 372.37 | 250 MG
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only and has not been fully validated for medical applications.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 98% | 372.37 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 0,0'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 25 MG
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Bis-aminooxy-PEG3 (HY-140409) is a chemical compound with a molecular formula of C8H20N2O5. It has a CAS number of 98627-70-4 and a purity of 98.0%. This product is stored at 4°C, protected from light. In solvent, it should be stored at -80°C for 6 months or -20°C for 1 month, also protected from light. It is intended for research use only.
- Chemical name: 0,0'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine]
- Molecular formula: C8H20N2O5
- Purity: 98.0%
- CAS number: 98627-70-4
- Appearance: Colorless to light yellow liquid
- Storage conditions: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
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eMolecules 77544-68-4 | Tos-PEG3 | ChemScene | MFCD18433414 | 304.360 | C13H20O6S | 96.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 100mg | 536796555
Tos-PEG3 | ChemScene | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 96.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 100mg | 536796555
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 372.37 | 1G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More