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Filtered Search Results
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 5 MG
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Aminooxy-PEG3-azide is a bifunctional PEG linker containing an aminooxy group and an azide handle for oxime ligation and azide-alkyne click chemistry. It is supplied as a liquid and is used for ADC and PROTAC linker synthesis, and for general bioconjugation and small-molecule assembly.
- Bifunctional: aminooxy and azide reactive groups.
- Peg3 spacer provides hydrophilicity and flexibility.
- Suitable for oxime formation with carbonyls and CuAAC click reactions.
- Purity typically 95.0%.
- Stable when stored at -20°C; in solvent short-term storage at lower temperatures recommended.
- Available in small research quantities, such as 5 mg.
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Medchemexpress LLC Bis-PEG5-acid 1g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 1 G
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Bis-PEG5-acid is a polyethylene glycol (PEG) linker bearing two terminal carboxylic acid groups, used as a hydrophilic spacer in PROTAC construction and bioconjugation chemistry. It facilitates coupling reactions and improves aqueous solubility for assembled molecules.
- Two terminal carboxylic acid groups enable standard amide coupling reactions.
- PEG5 spacer provides hydrophilicity and conformational flexibility.
- Molecular weight 338.35 g/mol and formula C14H26O9 for precise stoichiometry.
- Suitable for PROTAC synthesis and general linker applications in medicinal chemistry.
- Offered in research quantities including 1 g for small-scale synthesis.
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 1 MG
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(S,R,S)-AHPC-C2-PEG3-BCN is a VHL ligand used for the synthesis of PROTACs. This product is intended for research use only.
- VHL ligand
- Used for the synthesis of PROTACs
- For research use only
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Medchemexpress LLC PEG3-C4-OBn | 2381196-79-6 | 99.3% | 250 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of PROTAC SGK3 degrader-1, a potent SGK3 degrader based on PROTAC technology. This product is for research use only.
- Molecular weight: 296.40
- Formula: C17H28O4
- Appearance: Liquid (density: 1.031 g/cm³)
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US
- Pure form storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- In vitro solubility: ≥ 100 mg/mL in DMSO
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Medchemexpress LLC Methoxy-PEG3 tosylate | 62921-74-8 | MFCD13184964 | 98.8% | 318.39 g/mol | C14H22O6S | 250 MG
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m-PEG3-Tos is a methoxy-terminated PEG3 tosylate used as a short, flexible PEG linker and intermediate in small-molecule synthesis. It provides three ethylene glycol units with a tosylate leaving group, making it suitable for nucleophilic substitution to install PEG chains and build PROTAC linkers or other conjugates.
- Provides three ethylene glycol units for short, flexible spacing.
- Contains a tosylate leaving group suitable for nucleophilic substitution.
- High purity (98.75%) appropriate for synthetic applications.
- Available in small-scale quantities for research use, such as 250 mg.
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Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | 99.0% | C11H25NO5 | 250 MG
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m-PEG5-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules consisting of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Purity: 99.02%
- Molecular weight: 251.32
- Formula: C11H25NO5
- CAS number: 5498-83-9
- Appearance: Liquid (density: 1.023±0.06 g/cm³)
- Color: Colorless to light yellow
- SMILES: COCCOCCOCCOCCOCCN
- Leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC Azido-PEG5-CH2CO2H | 217180-81-9 | 98.9% | 321.33 g/mol | C12H23N3O7 | 250 MG
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Azido-PEG5-CH2CO2H is a cleavable, azide-functionalized polyethylene glycol (PEG) linker with a terminal carboxylic acid that provides a hydrophilic spacer and a reactive azide handle for bioconjugation and linker synthesis.
- Cleavable 5-unit PEG linker suitable for linker-based conjugation.
- Azide functional group for copper-catalyzed or strain-promoted click reactions.
- Terminal carboxylic acid enables further derivatization or coupling.
- Hydrophilic spacer increases solubility in aqueous media.
- High purity suitable for chemical synthesis and bioconjugation.
- Available in 250 MG pack size.
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Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | >95.0% | C19H32N2O5 | 10MG
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BCN-exo-PEG3-NH2 is a BCN-functionalized PEG3 amine linker used in bioorthogonal conjugation and PROTAC linker synthesis. It provides a strained alkyne handle and a terminal primary amine to enable modular coupling strategies, and is commonly supplied in research-scale quantities at high reported purity.
- Provides a strained alkyne (BCN) for rapid bioorthogonal click reactions.
- Contains a PEG3 spacer for flexibility and improved solubility.
- Features a terminal primary amine for amide or reductive amination conjugation.
- Suitable for linker construction in targeted degradation and bioconjugation workflows.
- Supplied in research-scale quantities with supplier-reported high purity.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 1 G
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Applicable in cancer and cancer targeted therapy research
- Classified as PROTAC linkers
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Medchemexpress LLC DBCO-S-S-PEG3-biotin | 1430408-09-5 | 96.9% | 869.12 | 25 MG
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DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Used in the synthesis of PROTACs
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Medchemexpress LLC 5,8,11-Trioxa-2,14-diazahexadecanoic acid, 16-bromo-15-oxo-, 1,1-dimethylethyl ester | 1421933-39-2 | ≥98.0% | C15H29BrN2O6 | 500 MG
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by utilizing the ubiquitin-proteasome system, connecting ligands for an E3 ubiquitin ligase and the target protein via a linker.
- Suitable for PROTAC synthesis
- Utilizes PEG-based linker technology
- Facilitates targeted protein degradation
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Ambeed AMBEED
5000870716 METHYL-PEG3-BROMIDE 5GR
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Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Aminooxy-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand with a target protein ligand. This product is strictly for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 2,4-D isooctyl ester | 25168-26-7 | 97.2% | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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2,4-D isooctyl ester is a selective herbicide of the chlorophenoxy compound class.
- Higher boiling point
- Low volatility
- Low drift
- Utilized to manage broadleaf weeds in diverse environments such as crops, lawns, and forests
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Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More