Organo-Metalloid Compounds
Sigma Aldrich Ethyl 5-amino-1-isopropyl-1H-pyrazole-4-carboxylate
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Isopropyldimethylchlorosilane, 95%
CAS: 3634-56-8 Molecular Formula: C5H13ClSi Molecular Weight (g/mol): 136.69 MDL Number: MFCD00009917 InChI Key: YCXVDEMHEKQQCI-UHFFFAOYSA-N Synonym: isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane PubChem CID: 5102883 IUPAC Name: chloro-dimethyl-propan-2-ylsilane SMILES: CC(C)[Si](C)(C)Cl
Dimethylisopropylchlorosilane 90.0+%, TCI America™
CAS: 3634-56-8 Molecular Formula: C5H13ClSi Molecular Weight (g/mol): 136.69 MDL Number: MFCD00009917 InChI Key: YCXVDEMHEKQQCI-UHFFFAOYSA-N Synonym: isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane PubChem CID: 5102883 IUPAC Name: chlorodimethyl(propan-2-yl)silane SMILES: CC(C)[Si](C)(C)Cl
Allyloxytrimethylsilane 97.0+%, TCI America™
CAS: 18146-00-4 Molecular Formula: C6H14OSi Molecular Weight (g/mol): 130.262 MDL Number: MFCD00008643 InChI Key: MNMVKGDEKPPREK-UHFFFAOYSA-N Synonym: allyloxytrimethylsilane,allyl trimethylsilyl ether,silane, trimethyl 2-propenyloxy,trimethyl 2-propenyloxy silane,o-trimethylsilylallyl alcohol,trimethylallyloxysilane,allyloxy trimethylsilane,silane, trimethyl 2-propen-1-yloxy,trimethyl prop-2-en-1-yloxy silane,acmc-1boq9 PubChem CID: 87471 IUPAC Name: trimethyl(prop-2-enoxy)silane SMILES: C[Si](C)(C)OCC=C
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | ≥97.0% | 263.29 | C10H21N3O5 | 10 G
Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a terminal hydroxyl group. It functions as a non-cleavable, five-unit PEG spacer for bioconjugation and click chemistry applications.
- Contains azide (-N3) and terminal alcohol (-OH) functional groups.
- Water-soluble PEG linker suitable for click chemistry and PROTAC/ADC assembly.
- Molecular weight ~263.29 g/mol; formula C10H21N3O5.
- High purity, typically ≥97.0% by manufacturer specification.
- Available in multiple pack sizes, including 10 g.
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g·mol⁻¹ | C10H21N3O5 | 5 G
Azido-PEG5-alcohol is an azide-terminated polyethylene glycol linker containing five ethylene glycol units and a terminal primary alcohol, used as a water-soluble reagent for bioconjugation and linker synthesis. It is commonly applied in click chemistry and in the construction of antibody-drug conjugates and PROTACs.
- Azide functionality enables CuAAC and SPAAC click reactions.
- Water-soluble PEG5 spacer improves solubility and flexibility.
- Terminal primary alcohol provides a synthetic handle for derivatization.
- Suitable for ADC linker synthesis and PROTAC construction.
- Supplied as a solid with reported purity >97.0%.
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g/mol | C10H21N3O5 | 25 G
Azido-PEG5-alcohol is an azide-terminated polyethylene glycol (PEG) linker containing five ethylene glycol units that is used as a click-chemistry reagent and as a linker in bioconjugation workflows. It participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions and is supplied for research use only.
- Azide functional group for click chemistry
- Five-unit PEG spacer adds hydrophilicity and flexibility
- Suitable for antibody-drug conjugate and PROTAC linker synthesis
- Characterized by NMR and LC-MS, purity >97.0%
- Available in multiple package sizes, including 25 G
Medchemexpress LLC Azido-PEG3-alcohol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 500 MG
Azido-PEG3-alcohol is a PEG-based linker bearing a terminal azide and a terminal hydroxyl group. It is used as a click-chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and as a flexible spacer in PROTACs and bioconjugation workflows.
- Terminal azide enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Terminal hydroxyl allows further functionalization and conjugation.
- PEG3 spacer imparts hydrophilicity and flexible linkage between molecules.
- High purity suitable for synthetic and bioconjugation applications.
- Stable when stored at -20°C in pure form; solution stability is limited.
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 50 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 250 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Enables targeted protein degradation via the ubiquitin-proteasome system
- Facilitates connection between an E3 ubiquitin ligase ligand and a target protein ligand
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | MFCD20134131 | >97.0% | 263.29 g/mol | C10H21N3O5 | 250 MG
Azido-PEG5-alcohol is a 5-unit polyethylene glycol (PEG) linker bearing an azide and a terminal hydroxyl group, used as a click-chemistry reagent and as a non-cleavable PEG spacer in conjugation and PROTAC synthesis. Purity is ≥97.0%, molecular weight is 263.29 g/mol, and CAS number is 86770-68-5.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
- Non-cleavable 5-unit PEG spacer to improve solubility and flexibility.
- Available in multiple sizes, including 250 mg.
- High purity suitable for synthetic and conjugation applications.
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | > 96.0% | C25H52N2O11 | 100 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein.
- Composed of two distinct ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase and the other targets a specific protein.
- Leverages the intracellular ubiquitin-proteasome system.
- Achieves selective degradation of target proteins.
Medchemexpress LLC 14-azido-3,6,9,12-tetraoxatetradecan-1-ol | 86770-68-5 | 97.0% | 263.29 g/mol | C10H21N3O5 | 1 G
Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker with a terminal azide and a terminal alcohol, used for bioconjugation and linker installation. The azide group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions, while the PEG5 spacer improves solubility and flexibility for conjugation workflows.
- Terminal azide enables CuAAC and SPAAC click reactions.
- PEG5 spacer increases solubility and reduces steric hindrance.
- Suitable for use as a non-cleavable linker in conjugation chemistry.
- Colorless to light yellow liquid with high purity.
- Stable under recommended storage conditions for long-term use.
![Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000300804.png-250.jpg)
Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G
Azido-PEG3-alcohol (2-[2-(2-azidoethoxy)ethoxy]ethanol, CAS 86520-52-7) is an azide-terminated PEG3 linker designed for click chemistry conjugations and PROTAC linker assembly. It contains a terminal hydroxyl for further functionalization and an azide group compatible with both copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- Azide functional group enables CuAAC and SPAAC conjugations.
- PEG3 spacer increases aqueous solubility and flexibility.
- Small molecular weight (175.19 g/mol) minimizes steric hindrance.
- High purity suitable for synthetic applications and conjugation reactions.
- Terminal hydroxyl allows additional derivatization or coupling.
Medchemexpress LLC 1-phenyl-2,5,8,11,14-pentaoxahexadecan-16-ol | 57671-28-0 | MFCD06797154 | 98.6% | 328.40 g/mol | C17H28O6 | 1 G
BnO-PEG5-OH is a benzyl-terminated PEG5 primary alcohol used as a flexible linker in PROTAC synthesis. It provides a short polyethylene glycol spacer with a terminal benzyl-protected alcohol functionality that can be modified for conjugation to ligands and linkers.
- Provides a PEG5 spacer for flexibility and improved solubility.
- Benzyl-protected terminal alcohol enables selective deprotection and further functionalization.
- High purity suitable for medicinal chemistry and research use.
- Characterized by certificate of analysis, 1H NMR, and RP-HPLC documentation.
- Available in small pack sizes for synthetic applications.
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