Tetrahydrofuran
Medchemexpress LLC Tenuifoliside B | 139726-36-6 | 5 MG
Tenuifoliside B is a component isolated from Polygalae Radix. It inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. This compound demonstrates potential cognitive improvement and cerebral protective effects, and it has the potential to be an anti-AD lead compound.
- Demonstrates potential cognitive improvement
- Demonstrates cerebral protective effects
- Has the potential to be an anti-AD lead compound
eMolecules Tetrahydrofuran ACS | Oakwood Chemicals | 109-99-9 | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Tetrahydrofuran ACS | Oakwood Chemicals | 109-99-9 | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Medchemexpress LLC Ambroxide | 6790-58-5 | 236.39 | 50 MG
Ambroxide is a naturally occurring terpenoid and a key constituent of ambergris. It is used in the manufacture of high-end perfumes to improve aroma quality and fragrance lasting time.
- Molecular weight: 236.39
- Formula: C16H28O
- CAS No.: 6790-58-5
- Appearance: Solid
- Color: White to off-white
- Structure classification: Terpenoids, other terpenoids
- Initial source: Plants (other families), animals (Physeter catodon L.)
- Purity: 98.0%
- Solubility in vitro: Soluble in DMSO (25 mg/mL)
Medchemexpress LLC SU5214 | 186611-04-1 | 98.0% | 251.28 | 5 MG
SU5214 is a potent VEGFR2 inhibitor. It has been extracted from patent US5834504A and exhibits IC50s of 14.8 μM for FLK-1 and 36.7 μM for EGFR.
- Potent VEGFR2 inhibitor.
- Targets VEGFR.
- Acts on the Protein Tyrosine Kinase/RTK pathway.
- Soluble in DMSO at 100 mg/mL.
- Suitable for research purposes.
Medchemexpress LLC Rhodojaponin III | 26342-66-5 | 5 MG
Rhodojaponin III is a diterpenoid extracted from the leaves of Rhododendron molle. It exhibits anti-inflammatory activity, demonstrated by its IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells. This compound has a molecular weight of 368.46 and a chemical formula of C20H32O6. It typically appears as a white to off-white solid.
- Extracted from the leaves of Rhododendron molle
- Exhibits anti-inflammatory activity
- Has an IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells
- Molecular weight is 368.46
- Chemical formula is C20H32O6
- Appears as a white to off-white solid
- Intended for research use only
Medchemexpress LLC PD-1/PD-L1-IN-23 | 2597056-04-5 | 99.9% | C32H30BrCl2N3O6 | 50 MG
PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. It is an ester proagent of L7, a benzo[c]oxadiazole derivative biologically evaluated as an inhibitor of PD-L1. It has shown significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice.
- Potent and orally active inhibitor of PD-1/PD-L1
- Ester proagent of L7, a benzo[c]oxadiazole derivative
- Displays significant antitumor effects in tumor models
- For research use only
Medchemexpress LLC AVJ16 | 2775241-92-2 | 99.6% | C28H27N3O4 | 100 MG
AVJ16 is a cancer cell migration inhibitor targeting the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with an affinity (Kd) of 1.4 μM. It interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation, inhibiting proliferation, invasion, and migration of IGF2BP1-expressing lung adenocarcinoma cells. It also suppresses colony formation and spheroid growth, induces apoptosis in certain cell lines, and demonstrates antitumor activity in xenograft mouse models.
- Targets IGF2BP1, a key protein in cancer cell migration.
- Interferes with mRNA binding to regulate gene expression.
- Inhibits proliferation, invasion, and migration of lung adenocarcinoma cells.
- Suppresses colony formation and spheroid growth.
- Induces apoptosis in relevant cell lines.
- Shows antitumor activity in xenograft mouse models.
Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.8% | 842.88 | 50 MG
AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. It exerts antineoplastic activity. Alflutinib is an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exerts antineoplastic activity
- EGFR inhibitor
- Yellow to orange solid
- Store at 4°C, sealed, away from moisture and light
- In solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Su 5214 | 186611-04-1 | MFCD01595259 | >98.0% | 10 MG
SU5214 is a small-molecule tyrosine kinase inhibitor reported to inhibit vascular endothelial growth factor receptor 2 (VEGFR2/FLK-1) and epidermal growth factor receptor (EGFR) in cell-free assays. It is used for biochemical studies and target validation involving VEGFR2/EGFR signaling pathways.
- Reported IC50 of 14.8 μM for VEGFR2 (cell-free assay).
- Reported IC50 of 36.7 μM for EGFR (cell-free assay).
- CAS number 186611-04-1.
- Molecular weight 251.285 g·mol⁻¹.
- Purity greater than 98% (HPLC) as supplied by chemical vendors.
- Supplied in small milligram quantities suitable for in vitro assays.
![Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232665.png-250.jpg)
Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG
MST-312 (Telomerase Inhibitor IX) is a small-molecule telomerase inhibitor derived from epigallocatechin gallate (EGCG). It is supplied as a white to off-white solid for laboratory research in oncology and telomerase studies.
- Telomerase inhibitor for cancer research.
- Chemically modified derivative of epigallocatechin gallate (EGCG).
- Molecular formula C20H16N2O6 and molecular weight 380.35 g·mol⁻1.
- Purity 98.6%.
- Supplied as a solid with common solubility in DMSO for solution preparation.
Medchemexpress LLC Naz2329 | 2809469-05-2 | 99.0% | 501.56 g/mol | C21H18F3NO4S3 | 25 MG
NAZ2329 is a small-molecule inhibitor of PTPRZ and PTPRG intended for research use. It is supplied as a 25 mg research sample and is characterized by high purity and defined physicochemical properties suitable for biochemical and in vivo studies.
- Inhibits PTPRZ and PTPRG activity.
- High purity: 99.02%.
- Molecular formula: C21H18F3NO4S3; molecular weight: 501.56 g/mol.
- Soluble in DMSO; in vitro solubility reported at 100 mg/mL.
- Provided as a 25 mg sample suitable for preliminary biochemical and in vivo assays.
Medchemexpress LLC L-Alanine, N-phosphono-, P→6-ester with 2-C-(4-aminopyrrolo[2,1-f]triazin-7-yl)... | 1911579-04-8 | 97.86% | 442.32 | 1 MG
GS-704277 is an alanine metabolite of Remdesivir. It is further hydrolyzed to GA-441524, a compound with antiviral activity. Remdesivir, a nucleoside analogue, is effective against SARS-CoV-2 (COVID-19) infection.
- Alanine metabolite of Remdesivir
- Further metabolized to GA-441524, which exhibits antiviral activity
- Related to Remdesivir, a nucleoside analogue effective against SARS-CoV-2 (COVID-19) infection
- Functions as a drug metabolite
- Involves the metabolic enzyme/protease pathway
eMolecules Ambeed / 3-(Bis(benzyloxy)phosphoryl)propanoic acid / 1g / 525098833 / A181500 / / 805243-04-3 / MFCD08064320 / 334.308 / C17H19O5P
Ambeed / 3-(Bis(benzyloxy)phosphoryl)propanoic acid / 1g / 525098833 / A181500 / / 805243-04-3 / MFCD08064320 / 334.308 / C17H19O5P
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 2l
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 2l
Medchemexpress LLC Onjisaponin B | 35906-36-6 | 99.1% | 10 MG
Onjisaponin B is a natural triterpenoid saponin isolated from Polygala tenuifolia with reported neuroprotective and autophagy-enhancing activity. It is used in cell-based and preclinical studies investigating protein aggregation, neurodegeneration, and inflammatory signaling.
- Natural triterpenoid saponin derived from Polygala tenuifolia.
- Inhibits NF-κB p65 and modulates inflammatory signaling.
- Enhances autophagy and promotes degradation of mutant α-synuclein and huntingtin.
- High purity solid powder (99.1%).
- Supplied as a 10 mg quantity suitable for research-scale assays.
- Intended for mechanistic studies and preclinical pharmacology models.