Tetrahydrofuran
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor
Tetrahydrofuran (THf) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi200L
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran is an environmentally favorable alternative to tetrahydrofuran (THf) 1 4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications. Many of its benefits include High boiling pointClean organic-water phase separationReduced energy to recover
Medchemexpress LLC Selnoflast | 2260969-36-4 | MFCD34579587 | 99.5% | 391.53 g/mol | C20H29N3O3S | 5 MG
Selnoflast is an orally active, selective, and reversible small-molecule inhibitor of the NLRP3 inflammasome, developed for research into inflammatory pathways and disease models. It is supplied for research use and is characterized by analytical data to support reproducible experimental use.
- Selective inhibitor of the NLRP3 inflammasome.
- Orally active and reversible small-molecule mechanism.
- Suitable for in vitro and in vivo inflammatory disease research.
- High purity supporting analytical consistency.
- Soluble in DMSO for standard assay formulations.
- Molecular weight 391.53 g/mol; molecular formula C20H29N3O3S.
Medchemexpress LLC Pelcitoclax (APG-1252) | 1619923-36-2 | 99.7% | 1281.85 g·mol⁻¹ | C57H66ClF4N6O11PS4 | 5 MG
Pelcitoclax is a small-molecule dual inhibitor of Bcl-2 and Bcl-xL used in oncology research. It induces apoptosis and has demonstrated antitumor activity in preclinical models, and is supplied with characterized molecular properties and high analytical purity for research applications.
- Dual Bcl-2 and Bcl-xL inhibition mechanism
- Promotes apoptosis in tumor cells
- Demonstrated antitumor activity in preclinical studies
- High analytical purity for consistent results
- Available as solid and ready-to-use DMSO solution formats
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofurfuryl alcohol
Tetrahydrofurfuryl alcohol is one of the aroma constituents of coffee.
Medchemexpress LLC BMS-1001 hydrochloride | 2113650-04-5 | 98.0% | 25 MG
A small-molecule hydrochloride salt developed as an orally active inhibitor of the PD-1/PD-L1 immune checkpoint. Intended for preclinical research applications, it is supplied at research-grade purity with batch-specific documentation.
- Orally active PD-1/PD-L1 inhibitor for immunology research.
- Hydrochloride salt form to improve solubility.
- High purity suitable for preclinical studies (≈98.0%).
- Available in small-scale quantities for screening and assays.
- Supplied with certificate of analysis and batch data.
Medchemexpress LLC Sonlicromanol | 1541170-75-5 | 99.8% | 25MG
Sonlicromanol | 1541170-75-5 | 99.8% | 25MG
![Medchemexpress LLC N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide | 368449-04-1 | 98.6% | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232288.png-250.jpg)
Medchemexpress LLC N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide | 368449-04-1 | 98.6% | 25MG
N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide | 368449-04-1 | 98.6% | 25MG
Medchemexpress LLC GSK3182571 | 2135595-04-7 | 99.8% | 495.02 g/mol | C25H31ClN8O | 50MG
GSK3182571 is a non-selective, broad-spectrum pan-kinase inhibitor provided as a solid powder for research use. It is intended for in vitro and cell-based studies to probe kinase networks and off-target effects; not for human use.
- High purity (99.75%).
- Molecular weight 495.02 g/mol.
- Molecular formula C25H31ClN8O.
- Soluble in DMSO at 100 mg/mL (202.01 mM) with ultrasonic aid and pH adjustment.
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- White to light yellow solid appearance.
Medchemexpress LLC DS08210767 | 2376334-75-5 | 99.4% | 513.67 | C31H39N5O2 | 25MG
DS08210767 is a small-molecule antagonist of the parathyroid hormone receptor 1 (PTHR1) for research use. It is reported to be orally bioavailable and shows an in vitro IC50 of 90 nM against PTHR1. The compound is supplied as a light yellow to yellow solid with high reported purity and is intended for biochemical and cellular studies; follow manufacturer storage recommendations.
Medchemexpress LLC Bevurogant (BI 730357) | 1817773-66-2 | 99.5% | C26H28N8O3S | 10MG
Bevurogant (BI 730357) is a retinoid-related orphan receptor-gamma t (RORγt) antagonist supplied as a high-purity research compound for in vitro and preclinical studies of chronic inflammatory diseases.
- Retinoid-related orphan receptor-gamma t antagonist.
- High purity: 99.5%.
- Molecular formula: C26H28N8O3S.
- Offered as a 10 mg research quantity.
- Provided with chemical identifiers for research use.
![Medchemexpress LLC 1-[[4-[4-[[4-(4-chloro-N-methylanilino)quinolin-1-ium-1-yl]methyl]phenyl]phenyl]methyl]-N-(4-chlor... | 850807-63-5 | 98.4% | 877.53 g/mol | C46H38Br2Cl2N4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211949.png-250.jpg)
Medchemexpress LLC 1-[[4-[4-[[4-(4-chloro-N-methylanilino)quinolin-1-ium-1-yl]methyl]phenyl]phenyl]methyl]-N-(4-chlor... | 850807-63-5 | 98.4% | 877.53 g/mol | C46H38Br2Cl2N4 | 5 MG
RSM-932A is a small-molecule choline kinase α (ChoKα) inhibitor used as a research tool in preclinical oncology studies. It shows potent antiproliferative activity in vitro and antitumor efficacy in vivo, and is commonly used to study ChoKα biology and evaluate therapeutic hypotheses in cellular and animal models.
- Selective ChoKα inhibitor with reported IC50 ≈ 1 μM and ~33 μM for ChoKβ.
- Potent antiproliferative activity across tumor-derived cell lines.
- Demonstrated antitumor efficacy in xenograft models.
- High-purity synthetic compound suitable for research applications.
- Solid form; molecular weight 877.53 g/mol.
- Store sealed at 4°C; long-term storage in solution recommended at -80°C.