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Filtered Search Results
Medchemexpress LLC 5-chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol | 315698-36-3 | MFCD02330713 | >=98.0% | 354.83 g/mol | C19H19ClN4O | 5 MG
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MLS1547 is a small-molecule, G protein-biased agonist of the dopamine D2 receptor used in research to probe receptor signaling bias. It preferentially stimulates G protein-mediated signaling with micromolar potency while showing reduced β-arrestin recruitment, making it useful for studies of biased agonism and D2 receptor pharmacology.
- Preferentially activates G protein signaling over β-arrestin pathways.
- D2 receptor agonist activity (Ki ≈ 1.2 μM; EC50 ≈ 0.37 μM).
- Antagonizes dopamine-stimulated β-arrestin recruitment (IC50 ≈ 9.9 μM).
- High purity suitable for biochemical assays (≥98% HPLC).
- Supplied in small research quantities for laboratory studies.
- Store refrigerated at +4 °C to maintain stability.
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Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 1 L
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 1 L
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Chemscene ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
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Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran is an environmentally favorable alternative to tetrahydrofuran (THf) 1 4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications. Many of its benefits include High boiling pointClean organic-water phase separationReduced energy to recover
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Medchemexpress LLC Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
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Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
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Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.2% | 348.44 | 10 MG
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BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor. It has an IC50 of 64 nM for MRCKβ in SCC12 cells, and Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β respectively. It demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation. This product is for research use only.
- Targets MRCKα (0.0136 nM (Ki)) and MRCKβ (0.0233 nM (Ki))
- Shows antiproliferative effects with greatest activity in hematologic cancer cells
- Inhibits MLC phosphorylation and blocks SCC12 squamous cell carcinoma motility and invasion
- Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes
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Ambeed 1-OXASPIRO(4.5)DECAN-2-O,250MG
1-Oxaspiro[4.5]decan-2-one | CAS No. 699-61-6 | MDL No.: MFCD00459846 | Formula: C9H14O2
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Medchemexpress LLC Ceftaroline | 189345-04-8 | 98.5% | 604.70 | C22H20N8O5S4 | 5 MG
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Ceftaroline is an N-phosphono-type cephalosporin, the active metabolite form used in research to evaluate antibacterial activity against gram-positive and gram-negative organisms. It is supplied as a white to yellow solid for laboratory use and is suitable for in vitro and preclinical assays.
- Antibacterial cephalosporin active metabolite.
- Suitable for in vitro and preclinical research.
- Supplied as a solid, white to yellow appearance.
- Available in small vial sizes for assay work.
- High reported purity (98.5%).
- Molecular weight 604.70.
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Medchemexpress LLC Rifalazil 100mg | 129791-92-0 | 100MG
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Rifalazil (KRM-1648 ABI-1648) a rifamycin derivative inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the -subunit in RNA polymerase[1 Rifalazil (KRM-1648 ABI-1648) is an antibiotic exhibits high potency against mycobacteria gram-positive bacteria Helicobacter pylori C pneumoniae and C trachomatis with MIC values from 0 00025 to 0 0025 g/ml[3 Rifalazil (KRM-1648 ABI-1648) has the potential for the treatment of Chlamydia infection Clostridium difficile associated diarrhea (CDAD) and tuberculosis (TB)[2
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Medchemexpress LLC GW406108X 10mg | 1644443-92-4 | 10 MG
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Small-molecule research inhibitor of Kif15 and ULK1 that blocks autophagic flux and is used in cellular and biochemical studies to probe autophagy and kinesin-related pathways. CAS 1644443-92-4; molecular formula C20H11Cl2NO4; molecular weight 400.21 g/mol.
- Selective Kif15 ATPase inhibitor (IC50 0.82 μM).
- ATP-competitive ULK1 inhibitor (pIC50 6.37; ~427 nM).
- High purity solid for research (98.0% reported by supplier).
- Molecular formula C20H11Cl2NO4; molecular weight 400.21 g/mol.
- Recommended storage: powder at -20 °C for long term or 4 °C for short term; in solution store at -80 °C for extended periods.
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Medchemexpress LLC Nerigliatin | 1245603-92-2 | MFCD26960571 | 99.9% | 432.43 g·mol⁻¹ | C22H20N6O4 | 100 MG
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Nerigliatin is a small-molecule glucokinase activator provided for laboratory research use. It is used in preclinical studies to evaluate glucose-lowering effects and glucokinase modulation. Supplied as a powdered compound, it is intended for in vitro and in vivo research applications; not for human or veterinary use.
- Glucokinase activator for studying glucose metabolism.
- High purity (≈99.9%) suitable for analytical and biological assays.
- Chemical formula C22H20N6O4; molecular weight 432.43 g·mol⁻¹.
- Available in multiple pack sizes including 100 MG.
- For research use only; not intended for clinical or veterinary applications.
- Follow safety data sheet for handling and storage recommendations.
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Medchemexpress LLC CSF1R-IN-1 | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 100 MG
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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with subnanomolar enzymatic potency (IC50 = 0.5 nM). It has demonstrated good intestinal permeability and favorable oral pharmacokinetics in mice, supporting its use in preclinical in vivo pharmacology studies related to tumor-associated macrophage biology, cancer, and inflammation research.
- Potent CSF1R inhibition (IC50 = 0.5 nM).
- Suitable for preclinical in vivo pharmacology studies.
- Demonstrates good intestinal permeability in Caco-2 assays.
- Favorable oral pharmacokinetic profile in mice.
- Available in solid and DMSO solution formats for dosing flexibility.
- High reported purity for research use.
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Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran anhydrous1L
Tetrahydrofuran (THf) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms double hydrate with hydrogen sulfide crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies.
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eMolecules 109-99-9 | Tetrahydrofuran ACS | Oakwood Chemicals | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Tetrahydrofuran ACS | Oakwood Chemicals | 109-99-9 | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
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Medchemexpress LLC 1-[[4-[4-[[4-(4-chloro-N-methylanilino)quinolin-1-ium-1-yl]methyl]phenyl]phenyl]methyl]-N-(4-chlorop | 850807-63-5 | 98.4% | 877.53 | C46H38Br2Cl2N4 | 50 MG
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Selective choline kinase alpha (ChoKα) inhibitor for biochemical and cell-based cancer research. It demonstrates potent in vitro anti-proliferative activity and in vivo antitumor efficacy in xenograft models. Supplied as a solid for laboratory use in small-scale quantities.
- Selective ChoKα inhibition (IC50 ≈ 1 μM).
- Activity against multiple tumor-derived cell lines (IC50 ~1.3-7.1 μM).
- High purity (98.4%).
- Molecular weight 877.53; CAS 850807-63-5.
- Storage: 4 °C sealed; in solvent -80 °C (6 months), -20 °C (1 month).
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