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Filtered Search Results
Medchemexpress LLC Deacylmetaplexigenin 5mg | 5MG
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Deacylmetaplexigenin 5mg | 5MG
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Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | 109-99-9 | MFCD00005356 | 100ML
Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | Purity: >=99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 100ML
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eMolecules Medchem Express / Broflanilide / 5mg / 559839407 / HY-108689 / / 1207727-04-5 / [null] / 663.285 / C25H14BrF11N2O2
Medchem Express / Broflanilide / 5mg / 559839407 / HY-108689 / / 1207727-04-5 / [null] / 663.285 / C25H14BrF11N2O2
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Jade Scientific, Inc TETRAHYDROFURAN LAB PLUS 19L
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Tetrahydrofuran Lab Plus 19l. 109-99-9 MFCD00005356
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Medchemexpress LLC Dalpiciclib | 5MG
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Dalpiciclib (SHR-6390) is an orally active and highly selective inhibitor of CDK4 and 6 with IC50 values of 12 4 nM and 9 9 nM respectively[1][2] Dalpiciclib shows antitumor activity against breast cancer and esophageal squamous cell carcinoma[1][2][3][4]
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Medchemexpress LLC (E)-1-(4-methoxyphenyl)-3-(4-morpholin-4-yl-6-nitroquinolin-2-yl)prop-2-en-1-one | 2313528-04-8 | 97.0% | C23H21N3O5 | 10MG
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hnRNPK-IN-1 is a small-molecule ligand that binds heterogeneous nuclear ribonucleoprotein K (hnRNPK), disrupting hnRNPK interaction with the c-myc promoter to inhibit c-myc transcription and induce apoptosis in cell-based assays. Binding affinities were measured by SPR and MST, and the compound is supplied as a solid for research use.
- Binds hnRNPK and disrupts hnRNPK-c-myc promoter interaction.
- Inhibits c-myc transcription and induces apoptosis in HeLa cell assays.
- Measured binding affinities: SPR Kd 4.6 μM, MST Kd 2.6 μM.
- High purity (97.0%) solid, brown to orange in appearance.
- Soluble in DMSO (~5 mg/mL) with warming and sonication.
- Store powder at -20°C (long-term) and solvent solutions at -80°C when possible.
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Medchemexpress LLC Az12601011 | 2748337-86-0 | 99.8% | 50 MG
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AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor (also inhibits ALK4 and ALK7) used as a research reagent to study TGF-β signaling and tumor models. It inhibits SMAD2 phosphorylation with reported potency (IC50 18 nM; Kd 2.9 nM) and has shown antitumor activity in vivo. High-purity powder and DMSO stock solutions are available.
- Selective TGFBR1, ALK4, and ALK7 inhibition.
- Biochemical potency: IC50 18 nM; Kd 2.9 nM.
- High purity (99.78%).
- Available as powder and DMSO solution for in vitro studies.
- Recommended storage: powder -20°C for long term, and solutions -80°C.
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Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)ca | 1224964-36-6 | 98.25% | 548.92 | 100 MG
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XL-784 is a selective inhibitor of matrix metalloproteinases (MMP). It shows IC50 values of approximately 1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. XL-784 is a highly potent, low-molecular-weight (1,122 g/mol) MMP inhibitor with limited aqueous solubility (20 μg/mL). It potently inhibits MMP-2, MMP-13, and ADAM10 [TNF-α-converting enzyme (TACE)] activity in vitro, with IC50 values in the range of 1-2 nM. XL-784 also inhibits MMP-9 (IC50 ~20 nM) and ADAM17 (IC50 ~70 nM) activity, but exhibits low potency for MMP-1 inhibition (IC50 ~2,000 nM). In vivo studies show that XL-784 is effective in inhibiting aortic dilatation in mice.
- Selective matrix metalloproteinases (MMP) inhibitor
- Potently inhibits MMP-2, MMP-13, and ADAM10 in vitro
- Inhibits MMP-9 and ADAM17 in vitro
- Effective in inhibiting aortic dilatation in vivo
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eMolecules 6-OXASPIRO[2.5]OCTAN-1-AMINE HCL | 1779133-13-9 | MFCD26097093 | 1g
AstaTech | 6-OXASPIRO[2.5]OCTAN-1-AMINE HCL | 1g | 534090821 | AT12432 | 95.000 | 1779133-13-9 | MFCD26097093 | 163.650 | C7H14ClNO
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Medchemexpress LLC GSK3182571 | 2135595-04-7 | 99.8% | 495.02 g/mol | C25H31ClN8O | 100MG
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GSK3182571 is a small-molecule pan-kinase inhibitor for research use that modulates Akt signaling and the PI3K/Akt/mTOR pathway. It is provided as a 100 mg research sample intended for in vitro pharmacology and biochemical studies, including probing kinase networks and off-target effects in cellular models. The compound is typically stored at -20°C and is soluble in DMSO.
- Pan-kinase inhibitor active against Akt and related kinases.
- High purity suitable for research assays.
- Molecular formula C25H31ClN8O; molecular weight 495.02 g/mol.
- Soluble in DMSO for assay preparation.
- Intended for in vitro pharmacology and biochemical studies.
- Store at -20°C to maintain stability.
- Supplied as a 100 mg research sample.
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Medchemexpress LLC Gsk2983559 | 99.5% | 612.63 | 100 MG
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GSK2983559 is an orally active and potent receptor interacting protein 2 (RIP2) kinase inhibitor. It blocks many proinflammatory cytokine responses both in vivo and in human inflammatory bowel disease explant samples.
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Medchemexpress LLC GSK3182571 | 2135595-04-7 | 99.8% | 495.02 | C25H31ClN8O | 25MG
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GSK3182571 is a small-molecule pan-kinase inhibitor used for laboratory research to probe kinase signaling and assess off-target kinase effects in biochemical and cellular assays. The compound is supplied at high purity and is typically handled in DMSO; it is intended for research use only and not for human or clinical applications.
- Pan-kinase inhibitor for broad kinase profiling
- High purity suitable for biochemical and cellular assays
- Available in small research pack sizes
- Soluble in DMSO for assay preparation
- Intended for research use; not for clinical use
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Medchemexpress LLC Protogracillin | 54848-30-5 | 1 MG
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Protogracillin is a steroidal saponin isolated from the plant Dioscorea zingiberensis Wright. Steroidal saponins found in the rhizomes of this plant have the potential to reduce the risk of cardiovascular diseases through anti-thrombotic action. It is intended for research use only and not for sale to patients.
- It is a steroidal saponin.
- It is isolated from Dioscorea zingiberensis Wright.
- It has potential anti-thrombotic action.
- It has shown cytotoxicity against human CCRF-CEM cells with an IC50 of 1.77 μM.
- Its purity is 99.00%.
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eMolecules 2-METHYLTETRAHYDROFURAN 50G
5000161174 2-METHYLTETRAHYDROFURAN 50G
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eMolecules 3-IODOTETRAHYDROFURAN 5G
5000164560 3-IODOTETRAHYDROFURAN 5G
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