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Filtered Search Results
Medchemexpress LLC Ganodermanontriol | 106518-63-2 | 472.70 | 1 MG
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Ganodermanontriol is a sterol isolated from *Ganoderma lucidum* that induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. It also exhibits hepatoprotective activity and antiproliferative activity against human MCF7 and MDA-MB-231 breast cancer cells.
- Induces anti-inflammatory activity.
- Exhibits hepatoprotective activity.
- Suppresses growth of colon cancer cells through β-catenin signaling.
- Exhibits anti-melanogenic effects through regulation of CREB and MAPK signaling pathways.
- Inhibits breast cancer cell lines MCF-7 and MDA-MB-231.
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Medchemexpress LLC ETZ (C3-CA-DTZ) | 2989379-61-3 | 99.8% | C34H28N6O6 | 50 MG
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ETZ (C3-CA-DTZ) is a promising luciferase prosubstrate that can be activated in vivo by nonspecific esterase to enhance the brain delivery of luciferin. It is intended for research use only and not sold to patients. This compound appears as a solid with a light yellow to orange color.
- Promising luciferase substrate (prosubstrate)
- Activatable in vivo by nonspecific esterase
- Enhances brain delivery of luciferin
- For research use only
- Solid appearance, light yellow to orange color
- Molecular weight: 616.62
- Shipped at room temperature in continental US
- Store at -20°C, sealed, away from moisture and light (solid)
- Store at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture and light (in solvent)
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Medchemexpress LLC PD-1/PD-L1-IN-23 | 2597056-04-5 | 100.0% | C32H30BrCl2N3O6 | 100 MG
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PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. It is an ester proagent of L7, a benzo[c]oxadiazole derivative, and has demonstrated significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice. This product is intended for research use only.
- Potent and orally active inhibitor of PD-1/PD-L1
- Ester proagent of L7, a benzo[c]oxadiazole derivative
- Evaluated as a PD-L1 inhibitor
- Demonstrates significant antitumor effects in tumor models
- Intended for research use only
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Medchemexpress LLC Choerospondin | 81202-36-0 | 5 MG
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Choerospondin is a flavanone isolated from the bark of Choerospondias axillaris. It is intended for research use only.
- Purity of 99.87%
- Molecular weight of 434.39
- Molecular formula C21H22O10
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL (230.21 mM)
- Classified as a flavonoid, flavanone, phenol, and polyphenol
- Isolated from plants such as Leguminosae - Glycyrrhiza uralensis Fisch. and Anacardiaceae - Choerospondias axillaris
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Medchemexpress LLC Isoformononetin | 486-63-5 | 10 MG
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Isoformononetin is an analog of Daidzein with immunoprotective effects, inhibiting the differentiation of Th17 and B-cells lymphopoiesis to promote osteogenesis in estrogen-deficient bone loss conditions.
- Molecular formula: C₁₆H₁₂O₄
- Molecular weight: 268.26
- Storage: 4°C, protected from light; in solvent: -80°C for 6 months, -20°C for 1 month (protected from light)
- Solubility (in vitro): DMSO at 250 mg/mL (931.93 mM), requires ultrasonic
- Usage caution: Product has not been fully validated for medical applications; for research use only
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BIRCH BIOTECH LLC PRISTINE Tetrahydrofuran, HPLC Grade, 4 Liter, 4/case
PRISTINE Tetrahydrofuran, HPLC Grade, 4 Liter, 4/caseHigh-Purity Solvent for High-Performance Liquid Chromatography (HPLC)PRISTINE HPLC Grade Tetrahydrofuran (THF) is a high-purity solvent designed for high-performance liquid chromatography and other sensitive analytical applications. With its low levels of impurities and low UV absorbance, this THF grade ensures minimal background interference, supporting high accuracy in both qualitative and quantitative analyses. Ideal for applications requiring precise separation and detection, it provides consistent results critical to advanced research and industrial applications.
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Medchemexpress LLC 5-amino-6-methoxy-2-(3',4',5'-trimethoxyphenylsulfonyl)quinoline | 1346169-92-3 | MFCD32174244 | 99.6% | 404.44 | C19H20N2O6S | 25 MG
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A quinoline-derived research compound that acts as a microtubule-depolymerizing agent. It inhibits tubulin polymerization, induces mitotic arrest and c-Jun N-terminal kinase-mediated apoptosis, and can sensitize resistant cancer cell lines to mTOR pathway inhibitors. Supplied as a solid for laboratory research use.
- Microtubule-depolymerizing activity observed in cell assays.
- Induces mitotic arrest and JNK-mediated apoptosis.
- High purity (~99.6%) for reproducible results.
- Molecular weight 404.44; formula C19H20N2O6S.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation recommended.
- Available in small sample sizes (5 mg-100 mg); powder storage at -20°C.
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Medchemexpress LLC DS08210767 | 2376334-75-5 | 99.4% | 513.67 g/mol | C31H39N5O2 | 100MG
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DS08210767 is a small-molecule antagonist of parathyroid hormone receptor 1 (PTHR1), described as highly potent and orally bioavailable with an IC50 of 90 nM. It is provided as a research-grade, well-characterized compound suitable for receptor pharmacology and oral in vivo studies.
- High potency (IC50 of 90 nM) for PTHR1 inhibition.
- Orally bioavailable, enabling oral dosing in pharmacology studies.
- High purity (99.4%) as verified by certificate of analysis.
- Molecular weight 513.67 g/mol; formula C31H39N5O2.
- Analytical data available: COA, HNMR, and LCMS.
- Supplied in multiple milligram pack sizes for experimental flexibility.
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eMolecules 1-Oxaspiro[2.5]octane | 185-70-6 | MFCD00022348 | 1g
Combi-Blocks | 1-Oxaspiro[2.5]octane | 1g | 117571348 | ST-4626 | 97.000 | 185-70-6 | MFCD00022348 | 112.172 | C7H12O
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Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.4 g/mol | C22H15F3N2O7S | 5 MG
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Linzagolix is a non-peptide, orally active gonadotropin-releasing hormone (GnRH) receptor antagonist used in laboratory research into estrogen-dependent conditions such as uterine fibroids, endometriosis, and adenomyosis. Supplied as a small, high-purity solid for research use only (not for human or veterinary use).
- Non-peptide, orally active GnRH antagonist
- Applicable to uterine fibroids, endometriosis, and adenomyosis research
- High chemical purity suitable for analytical and pharmacological studies
- Supplied in a small 5 mg pack for assay development and pilot studies
- Molecular weight 508.4 g/mol
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eMolecules Ambeed / 3-Iodotetrahydrofuran / 100mg / 571783746 / A531490 / / 121138-01-0 / MFCD09878873 / 198.003 / C4H7IO
Ambeed / 3-Iodotetrahydrofuran / 100mg / 571783746 / A531490 / / 121138-01-0 / MFCD09878873 / 198.003 / C4H7IO
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Medchemexpress LLC Metsulfuron-methyl | 74223-64-6 | 99.6% | 100 MG
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Metsulfuron-methyl is a systemic sulfonylurea herbicide widely utilized for controlling broadleaf weeds and annual grasses in crops such as rice, corn, wheat, and barley.
- Demonstrates high herbicidal activity
- Low mammalian toxicity, with an LD50 for rats exceeding 5000 mg/kg
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Medchemexpress LLC Tmx-4116 | 2766385-56-0 | 99.8% | C17H19N5O4S | 100 MG
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TMX-4116 is a casein kinase 1α (CK1α) degrader. It exhibits a degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells.
- Can be utilized for research related to multiple myeloma.
- Demonstrates a high degradation preference for CK1α in MOLT4 cells at 1 μM for 4 hours.
- Induces primary target degradation of CK1α without downregulating PDE6D, IKZF1, and IKZF3 in MOLT4 cells.
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Medchemexpress LLC GSK3182571 | 2135595-04-7 | 99.8% | 495.02 g/mol | C25H31ClN8O | 50MG
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GSK3182571 is a non-selective, broad-spectrum pan-kinase inhibitor provided as a solid powder for research use. It is intended for in vitro and cell-based studies to probe kinase networks and off-target effects; not for human use.
- High purity (99.75%).
- Molecular weight 495.02 g/mol.
- Molecular formula C25H31ClN8O.
- Soluble in DMSO at 100 mg/mL (202.01 mM) with ultrasonic aid and pH adjustment.
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- White to light yellow solid appearance.
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Medchemexpress LLC Rsm-932a | 850807-63-5 | 98.4% | 877.53 g/mol | C46H38Br2Cl2N4 | 10 MG
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RSM-932A is a small-molecule choline kinase α (ChoKα) inhibitor used in oncology research. It has demonstrated in vitro antiproliferative activity across multiple tumor-derived cell lines and shown antitumor effects in preclinical models. Supplied as a purified research compound for laboratory use only (not for human or veterinary use).
- Potent choline kinase α inhibitor with demonstrated antiproliferative activity.
- Effective in both in vitro and in vivo preclinical studies.
- High purity suitable for biochemical and cellular assays.
- Molecular weight 877.53 g/mol supports mass-based dosing and analysis.
- Available in small lab-scale quantities for experimental workflows.
- Intended for research use only; not for human or veterinary applications.
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