Tetrahydrofuran
Medchemexpress LLC CCT369260 | 2647503-57-7 | 99.7% | 100 MG
CCT369260 is a chemical probe and an orally active B-cell lymphoma 6 (BCL6) inhibitor. It demonstrates anti-tumor activity and exhibits an IC50 of 520 nM.
- Orally active B-cell lymphoma 6 (BCL6) inhibitor
- Exhibits anti-tumor activity
- IC50 of 520 nM against BCL6
- Significantly inhibits BCL6 in OCI-Ly1 DLBCL xenograft model (in vivo study)
Medchemexpress LLC 9,19-Cyclolanostan-3-ol, 24-methylene-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenoate, (3β)- | 469-36-3 | 5 MG
24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. It promotes parvin-beta expression in human breast cancer cells and is a potential ATP-competitive Akt1 inhibitor.
- Purity of 98.53%
- White to off-white solid appearance
- Soluble in DMSO at ≥ 12.5 mg/mL
- Classified as a terpenoid and phenol
- Derived from plants
Medchemexpress LLC Ceftaroline 100mg | 189345-04-8 | 100MG
T-91825 (PPI-0903M) an N-phosphono-type cephalosporin is the active form of TAK-599 T-91825 is active against both gram-positive and gram-negative bacteria[1 [2
Medchemexpress LLC Bifenthrin | 82657-04-3 | 99.8% | 50 MG
Bifenthrin is a synthetic pyrethroid insecticide that prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, which disrupts neural function.
- Effective against *A. gambiae* and *C. quinquefasciatus*
- Demonstrates good lethality against susceptible and resistant mosquitoes
- Effectively inhibits blood sucking
- Suitable for development as a mosquito-removal netting material
Medchemexpress LLC Alendronic acid | 66376-36-1 | 98.0% | 100 MG
Alendronic acid is an orally active bisphosphonate that binds to bone surfaces and inhibits bone resorption by osteoclasts. It induces skeletal alterations in the chicken embryonic development model and can be used for osteoporosis research.
- Inhibits bone resorption by osteoclasts.
- Induces skeletal alterations in chicken embryonic development model.
- Useful for osteoporosis research.
- Orally active bisphosphonate.
Medchemexpress LLC Otaplimastat (SP-8203) | 1176758-04-5 | 98.1% | 534.61 | 100 MG
Otaplimastat (SP-8203) is a matrix metalloproteinase (MMP) inhibitor that competitively blocks N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity. It also exhibits anti-oxidant activity and can be used for the research of brain ischemic injury.
- Protects neuronal cells against NMDA-induced cell death.
- Inhibits Ca2+ influx following activation of NMDA receptors.
- Suppresses H2O2-induced cell death and reactive oxygen species production.
- Prevents ischemic neuronal death in an occlusion model of MCA.
- Attenuates impairment of stroke-induced motor function.
Medchemexpress LLC Pelcitoclax | 1619923-36-2 | 99.7% | 1281.85 | 1 ML
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects. In vitro, APG-1252 changes to the reactive metabolite named APG-1252-M1, which has remarkable antitumor effects in acute myeloid leukemia. Pelcitoclax treatment inhibits xenograft tumor growth more obviously than other groups. In an animal model using BALB/c athymic nude mice, intravenous injection of Pelcitoclax once a day for 10 days inhibited xenograft tumor growth.
Medchemexpress LLC Ambroxide | 6790-58-5 | 236.39 | 50 MG
Ambroxide is a naturally occurring terpenoid and a key constituent of ambergris. It is used in the manufacture of high-end perfumes to improve aroma quality and fragrance lasting time.
- Molecular weight: 236.39
- Formula: C16H28O
- CAS No.: 6790-58-5
- Appearance: Solid
- Color: White to off-white
- Structure classification: Terpenoids, other terpenoids
- Initial source: Plants (other families), animals (Physeter catodon L.)
- Purity: 98.0%
- Solubility in vitro: Soluble in DMSO (25 mg/mL)
Medchemexpress LLC Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
Medchemexpress LLC Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 50 MG
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 50 MG
![Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)ca | 1224964-36-6 | 98.25% | 548.92 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403415-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)ca | 1224964-36-6 | 98.25% | 548.92 | 100 MG
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP). It shows IC50 values of approximately 1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. XL-784 is a highly potent, low-molecular-weight (1,122 g/mol) MMP inhibitor with limited aqueous solubility (20 μg/mL). It potently inhibits MMP-2, MMP-13, and ADAM10 [TNF-α-converting enzyme (TACE)] activity in vitro, with IC50 values in the range of 1-2 nM. XL-784 also inhibits MMP-9 (IC50 ~20 nM) and ADAM17 (IC50 ~70 nM) activity, but exhibits low potency for MMP-1 inhibition (IC50 ~2,000 nM). In vivo studies show that XL-784 is effective in inhibiting aortic dilatation in mice.
- Selective matrix metalloproteinases (MMP) inhibitor
- Potently inhibits MMP-2, MMP-13, and ADAM10 in vitro
- Inhibits MMP-9 and ADAM17 in vitro
- Effective in inhibiting aortic dilatation in vivo
Medchemexpress LLC Nerigliatin | 1245603-92-2 | 99.9% | 432.43 g/mol | C22H20N6O4 | 50 MG
Nerigliatin is an orally active glucokinase activator supplied for research and analytical use. It has been studied for glucose-lowering effects in type 2 diabetes models and is associated with peripheral nerve degeneration in preclinical reports. The compound is provided as a high-purity solid for laboratory experiments.
- Orally active glucokinase activator.
- Intended for research and analytical applications.
- High purity (reported 99.94%).
- Molecular formula C22H20N6O4; molecular weight 432.43 g/mol.
- Available as a 50 mg solid package.
Medchemexpress LLC Tenuifoliside B | 139726-36-6 | 5 MG
Tenuifoliside B is a component isolated from Polygalae Radix. It inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. This compound demonstrates potential cognitive improvement and cerebral protective effects, and it has the potential to be an anti-AD lead compound.
- Demonstrates potential cognitive improvement
- Demonstrates cerebral protective effects
- Has the potential to be an anti-AD lead compound
eMolecules 1192-30-9 | TETRAHYDROFURFURYL BROMIDE | AstaTech | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 25g | 449775921
TETRAHYDROFURFURYL BROMIDE | AstaTech | 1192-30-9 | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 25g | 449775921
AccuStandard, Inc Tetrahydrofuran | 109-99-9 | MFCD00005356 | 5 x 1 mL
Tetrahydrofuran | 1000 µg/mL in Water | MW: 72.106 | 109-99-9 | MFCD00005356 | 5 x 1 mL
