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Filtered Search Results
Medchemexpress LLC Broflanilide | 1207727-04-5 | 99.0% | 663.28 | 100 MG
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Broflanilide is an insecticide that converts into Desmethyl-Broflanilide, a powerful antagonist at the insect RDL GABA Receptor. This mechanism inhibits *S. litura* RDL GABAR with an IC50 of 1.3 nM. Desmethyl-Broflanilide shows limited activity against human GABAA α1β2γ2 receptor, mammalian GABAA α1β3γ2 receptor, and human glycine receptor (GlyR) α1β with IC50s greater than 3 μM, and less potent inhibition of GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM).
- Acts as a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor.
- Inhibits *S. litura* RDL GABAR.
- Exhibits weak activity against human and mammalian GABAA receptors.
- Less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G.
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Sigma Aldrich Fine Chemicals Biosciences 2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | 96-47-9 | MFCD00005367 | 4X4L
2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | Purity: >=99.5% | Mol Wt: 86.13 | 96-47-9 | MFCD00005367 | 4X4L
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Medchemexpress LLC PD-1/PD-L1-in-23 | 2597056-04-5 | C32H30BrCl2N3O6 | 10MG
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PD-1/PD-L1-IN-23 is a small-molecule research compound that inhibits the PD-1/PD-L1 immune checkpoint pathway. Supplied as a solid powder in milligram-scale packaging, it is intended for in vitro and preclinical studies to probe PD-1/PD-L1 interactions in biochemical and cellular assays.
- High purity (>98%).
- Chemical formula C32H30BrCl2N3O6; molecular weight 703.41 g/mol.
- Supplied as a solid powder suitable for dissolution in common laboratory solvents.
- Intended for in vitro and preclinical research use; not for clinical or human use.
- Useful for studies of PD-1/PD-L1 interaction and checkpoint inhibition assays.
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Medchemexpress LLC 3-fluoro-N-[(E)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide | 352336-36-8 | 99.4% | C17H12FN3O2S | 10MG
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HY-133511 (MLS000544460) is a selective, reversible inhibitor of Eya2 phosphatase used in biochemical and cellular research. It is supplied as a white to off-white solid (C17H12FN3O2S) with high reported purity and characterized potency for use in mechanism and preclinical studies.
- selective, reversible inhibition of Eya2 phosphatase
- high reported purity (99.42%) suitable for research assays
- characterized potency: Kd 2.0 μM and IC50 4 μM
- high solubility in DMSO (125 mg/mL) and formulatable for animal dosing
- powder storage stability: -20°C for up to 3 years
- white to off-white solid with molecular weight 341.36 g/mol
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000259194 L-HOMOPROPARGYLGLYCI 10MG
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eMolecules 890092-04-3 | Ambeed | 4-(Dimethylamino)picolinic acid | 100mg | 569096432 | A543061 | MFCD04971955 | 166.18 | C8H10N2O2
Ambeed | 4-(Dimethylamino)picolinic acid | 100mg | 569096432 | A543061 | 890092-04-3 | MFCD04971955 | 166.180 | C8H10N2O2
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Medchemexpress LLC Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
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Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
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Medchemexpress LLC Metsulfuron-methyl (Standard) | 74223-64-6 | 50 MG
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Metsulfuron-methyl (Standard) is the analytical standard of Metsulfuron-methyl. This product is intended for research and analytical applications. Metsulfuron-methyl is a systemic sulfonylurea herbicide that has been widely used to control broadleaf weeds and annual grasses in rice, corn, wheat, and barley. Metsulfuron-methyl exhibits high herbicidal activity and low mammalian toxicity, with an LD50 for rats exceeding 5000 mg/kg.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
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Medchemexpress LLC SU5214 | 186611-04-1 | 251.28 | 100 MG
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SU5214 is a potent VEGFR2 inhibitor. It is extracted from patent US5834504A and is suitable for research use. It acts on Protein Tyrosine Kinase/RTK pathway.
- Potent VEGFR2 inhibitor
- Target for VEGFR
- Inhibits FLK-1 with an IC50 of 14.8 μM
- Inhibits EGFR with an IC50 of 36.7 μM
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Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | 99.9% | C18H20Cl2N4 | 10MG
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L-745870 hydrochloride is the hydrochloride salt of a selective dopamine D4 receptor antagonist used in pharmacology research. It is brain-penetrant, orally active, and is employed to investigate D4 receptor activity and related neuropharmacological effects.
- Potent and selective dopamine D4 receptor antagonist (Ki 0.43 nM).
- Brain-penetrant and orally active for in vivo studies.
- High chemical purity suitable for research use (99.9%).
- Available as a solid or as a DMSO solution for flexibility in assays.
- Offered in multiple small-scale package sizes for preclinical experiments.
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SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES TETRAHYDROFURAN 1L LICHROSOLV
NC2025278 TETRAHYDROFURAN 1L LICHROSOLV
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Medchemexpress LLC Ac9-25 | 284040-76-2 | 98.1% | 2183.33 | 1 MG
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Ac9-25 is a N-terminal peptide of Annexin I that functions as a formyl peptide receptor (FPR) agonist. It activates neutrophil NADPH oxidase through FPR.
- N-terminal peptide of Annexin I
- Functions as a formyl peptide receptor (FPR) agonist
- Activates neutrophil NADPH oxidase
- Formula: C99H143N23O33
- Sequence: Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys
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Medchemexpress LLC MPT0B392 | 1346169-92-3 | MFCD32174244 | 99.6% | 404.44 | C19H20N2O6S | 50 MG
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MPT0B392 is an orally active quinoline-derived microtubule-depolymerizing agent that inhibits tubulin polymerization, activates c-Jun N-terminal kinase (JNK), and induces apoptosis. It is used in cellular assays and preclinical models to study microtubule dynamics and apoptosis signaling pathways.
- Inhibits tubulin polymerization and induces mitotic arrest.
- Activates c-Jun N-terminal kinase (JNK) and promotes apoptosis.
- High purity (99.6%) for reliable experimental results.
- Soluble in DMSO (≈100 mg/mL) for convenient formulation.
- Solid, light yellow appearance for easy inspection.
- Stable as powder at -20°C for up to 3 years.
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Medchemexpress LLC Morphiceptin | 74135-04-9 | 99.07% | 521.61 | 5 MG
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Morphiceptin is a potent and specific agonist for morphine (μ) receptors. This synthetic peptide is the amide of a fragment of the milk protein β-casein. It exhibits morphinelike activities and is highly specific for morphine (μ) receptors.
- Potent and specific agonist for morphine (μ) receptors
- Synthetic peptide derived from β-casein
- Exhibits morphinelike activities
- Inhibits binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with an IC50 of approximately 20 nM
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Medchemexpress LLC Morphiceptin | 74135-04-9 | 99.1% | 521.61 | 1 MG
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Morphiceptin is a potent and specific agonist for morphine (μ) receptors. It is a synthetic peptide, derived from β-casein. It exhibits morphinelike activities and shows high specificity for morphine (μ) receptors, inhibiting the binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with an IC50 of about 20 nM.
- Potent and specific agonist for morphine (μ) receptors
- Synthetic peptide derived from β-casein
- White to off-white solid appearance
- Soluble in water and DMSO
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