Tetrahydrofuran
Medchemexpress LLC N-(5-(((4-Me-1,2,5-thiadiazol-3-yl)thio)methyl)-1,3,4-thiadiazol-2-yl)-4-(4-(CF3)Ph)thiazol-2-amine | 2809469-05-2 | 99.0% | 501.56 g·mol⁻¹ | C21H18F3NO4S3 | 100 MG
NAZ2329 is a research-grade, cell-permeable small-molecule inhibitor that allosterically and preferentially targets the receptor-type protein tyrosine phosphatases PTPRZ and PTPRG. It has demonstrated inhibition of glioblastoma cell growth and suppression of stem cell-like properties in published studies. Supplied as a purified powder for laboratory research use.
- Allosteric inhibitor of PTPRZ and PTPRG.
- Demonstrated antiproliferative activity in glioblastoma models.
- High reported purity (99.02%).
- Soluble in DMSO (100 mg/mL); in vivo formulation protocols available.
- Recommended storage: powder at -20 °C for long-term stability.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran contains 2200L
Tetrahydrofuran (THf) is a widely used organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. The effect of THf on the biological systems has been studied.
Medchemexpress LLC L-Alanine, N-phosphono-, P→6-ester with 2-C-(4-aminopyrrolo[2,1-f]triazin-7-yl)... | 1911579-04-8 | 97.86% | 442.32 | 1 MG
GS-704277 is an alanine metabolite of Remdesivir. It is further hydrolyzed to GA-441524, a compound with antiviral activity. Remdesivir, a nucleoside analogue, is effective against SARS-CoV-2 (COVID-19) infection.
- Alanine metabolite of Remdesivir
- Further metabolized to GA-441524, which exhibits antiviral activity
- Related to Remdesivir, a nucleoside analogue effective against SARS-CoV-2 (COVID-19) infection
- Functions as a drug metabolite
- Involves the metabolic enzyme/protease pathway
Medchemexpress LLC N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | 98.0% | C93H177N3O3 | 50 MG
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3, an ionizable lipid-like material used for mRNA delivery. It presents as an oil, with a color ranging from off-white to light yellow.
- Analogue of TT3
- Ionizable lipid-like material
- Used for mRNA delivery
- Appears as an oil
- Off-white to light yellow color
![Medchemexpress LLC N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245949.png-250.jpg)
Medchemexpress LLC N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 50 MG
RSVA405 is a small-molecule research compound that potently activates AMP-activated protein kinase (AMPK) and is orally active in vivo. It facilitates CaMKKβ-dependent AMPK activation (EC50 = 1 μM), inhibits mTOR signaling, promotes autophagy and amyloid-β (Aβ) degradation, and shows anti-inflammatory activity via STAT3 inhibition.
- Potent AMPK activator (EC50 = 1 μM).
- Orally active small-molecule research compound.
- Promotes autophagy and increases Aβ degradation.
- Inhibits mTOR signaling and STAT3-mediated inflammation.
- High purity (≈99.7%) light yellow solid.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 50g | 480143992
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 50g | 480143992
Medchemexpress LLC Rhamnocitrin | 569-92-6 | MFCD00006839 | 300.26 | 1 MG
Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons, and is applicable for studying endothelial-related inflammatory diseases and neuroprotection.
- Scavenges DPPH (IC50=28.38 mM).
- Up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE).
- Blocks NFATc3 nuclear translocation and downstream inflammatory factor expression.
- Induces heme oxygenase HO-1 expression and regulates the ERK/p38 MAPK pathway.
- Inhibits antioxidant and pro-inflammatory cytokines (e.g., IL-6, IL-8) and adhesion molecules (e.g., ICAM-1, VCAM-1).
Medchemexpress LLC Decanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- | 31078-36-1 | 5 MG
N-Vanillyldecanamide is a capsaicinoid isolated from the fruits of Capsicum annuum. It significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner. It has a molecular weight of 307.43 and a chemical formula of C18H29NO3. Its appearance is a solid, white to off-white in color. It is for research use only.
- Capsaicinoid isolated from Capsicum annuum
- Significantly reduced radical length of Lactuca sativa seedling
- Molecular weight of 307.43
- Chemical formula of C18H29NO3
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC TMX-4100 | 2367619-63-2 | 98.2% | C11H10N4O2S | 100 MG
TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. It demonstrates a high degradation preference for PDE6D with DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. This compound can be utilized for research into multiple myeloma.
- Demonstrates a high degradation preference for PDE6D in MOLT4 cells.
- Exhibits better proteome-wide degradation selectivity in MOLT4 cells.
- Does not hinder the growth of KRAS-dependent cell lines.
Medchemexpress LLC N-vanillyldecanamide | 31078-36-1 | MFCD01233545 | 99.9% | 307.43 g·mol⁻¹ | C18H29NO3 | 10 MG
N-Vanillyldecanamide is a capsaicinoid research chemical (CAS 31078-36-1) isolated from the fruits of Capsicum annuum. It has been reported to reduce the radical length of Lactuca sativa seedlings in a dose-dependent manner. The compound is supplied for laboratory research use with supporting documentation for handling and analysis.
- High purity (99.86%) suitable for analytical and biological studies.
- Molecular formula C18H29NO3 and molecular weight 307.43 g·mol⁻¹.
- Supplied in small laboratory quantities, including a 10 mg pack size.
- Available as a solid and as 10 mM solutions in DMSO for convenience.
- Storage: keep at 4°C and protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Typical applications include capsaicinoid activity studies, plant physiology research, and structure-activity investigations.
- Product documentation includes datasheet, COA, and SDS for quality and safety reference.
Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.42 | 50 MG
Linzagolix is a potent, non-peptide, and orally active GnRH antagonist. It can be used for uterine fibroids, endometriosis, and adenomyosis research. For research use only.
- Potent, non-peptide, and orally active GnRH antagonist
- Used for uterine fibroids, endometriosis, and adenomyosis research
Medchemexpress LLC Acrylodan | 86636-92-2 | 95.1% | 225.29 g/mol | C15H15NO | 5 MG
Acrylodan is a thiol-reactive, environment-sensitive fluorescent dye that covalently labels cysteine residues and reports on local dipolarity and conformational dynamics within binding pockets such as Cys34.
- Reacts with thiols to form a covalent fluorescent adduct.
- Sensitive to local dipolarity and protein dynamics.
- Soluble in DMSO at approximately 50 mg/mL; ultrasonic agitation may be required.
- Purity approximately 95.1%; molecular weight 225.29 g/mol.
- Store protected from light; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 50 MG
CIL62 is a caspase-3/7-independent cell death inducer that operates via Necrostatin-1 dependent mechanisms. It exhibits antiproliferative activity against human COLO205, IMR32, and K562 cells.
- Caspase-3/7-independent cell death inducer
- Necrostatin-1 dependent mechanism of action
- Antiproliferative activity against COLO205, IMR32, and K562 cells
Medchemexpress LLC AZ12601011 | 2748337-86-0 | 99.8% | 100 MG
AZ12601011 is an orally active, selective TGFBR1 (ALK5) kinase inhibitor intended for laboratory research. It inhibits SMAD2 phosphorylation (IC50 = 18 nM; Kd = 2.9 nM), has demonstrated antitumor activity in preclinical models, and is provided with high analytical purity for biochemical assays.
- Selective TGFBR1 inhibition with low-nanomolar potency.
- Inhibits SMAD2 phosphorylation in signaling assays.
- High analytical purity suitable for biochemical studies.
- Supplied as a 100 mg solid for convenient dosing.
- For research use only; not for human or clinical use.