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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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LSD acetate is a peptide designed for targeted research in oncology. It specifically recognizes the lymphatics of C8161 melanoma, distinguishing them from normal tissues and tumor blood vessels. This peptide can reduce the number of tumor lymphatics when conjugated with a proapoptotic peptide, making it valuable for the development of targeted therapies and diagnostic tools for tumor lymphatics.
Specifically recognizes lymphatics of C8161 melanoma
Does not bind to lymphatics of normal tissues or tumor blood vessels
Reduces tumor lymphatics when conjugated with a proapoptotic peptide
Useful for targeted therapy and diagnosis of tumor lymphatics research
Molecular weight: 1009.20 (free base)
Appearance: Solid
Color: White to off-white
Sequence: Cys-Leu-Ser-Asp-Gly-Lys-Arg-Lys-Cys
Soluble in DMSO: 100 mg/mL (needs ultrasonic)
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Retinyl Vitamin A Palmitate is a stabilized ester derivative of retinol (Vitamin A) and palmitic acid It is designed to deliver bioavailable Vitamin A upon enzymatic hydrolysis releasing free retinol that functions as an active intermediate in visual function cellular differentiation gene expression regulation and immune responses via retinoid receptors Retinyl Vitamin A Palmitate exerts its biological activity primarily through enzymatic hydrolysis generating retinol that participates in retinoid-mediated signaling pathways Based on these pharmacological properties Retinyl Vitamin A Palmitate holds research potential in studies of retinoid signaling vitamin deficiency models dermatological processes and nutritional supplementation evaluations
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D-α-Tocopherol acetate (D-Vitamin E acetate) is a compound that can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine. It acts as an endogenous metabolite and is supplied as a colorless to light yellow liquid. This compound is intended for research use only.
Can be hydrolyzed to d-alpha-tocopherol and absorbed in the small intestine.
Inhibits LPS-induced production of NO, prostaglandin E2, and pro-inflammatory cytokines (TNF-α, IFN-γ, IL-1β, and IL-6) in mouse peritoneal macrophages.
Exhibits a slight suppression on the activation of NF-κB p50 and p65.
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rel-Bedaquiline is a drug impurity related to the anti-tuberculosis agent bedaquiline and is supplied as an analytical reference for research use only. It is intended for chromatographic and analytical method development, impurity profiling, and stability studies. Consult the Certificate of Analysis for batch-specific purity and storage conditions.
Intended for research use only; not for human or clinical use.
Impurity standard for analytical and chromatographic method development.
High purity reference: 97.56% by HPLC (batch dependent).
Suitable for impurity profiling and stability studies.
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Vitamin K1 is a naturally occurring vitamin essential for blood coagulation and bone and vascular metabolism. It is a prenylated naphthoquinone synthesized by plants, green algae, and some cyanobacteria, acting as an electron carrier in photosystem I.
Required for blood coagulation and bone and vascular metabolism in humans
Shows significant antiproliferative effects and induces apoptosis in Caco-2, HT-29, and SW480 cell lines
Increased dietary intake is associated with a reduced risk of incident diabetes
Supplementation reverses high-fat diet-induced bone deterioration
Topical application suppresses pigmentation and resolves bruising, promoting wound repair
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Vitamin K4 is a chemically synthesized Vitamin K that plays an important role in the normal blood coagulation system. It arrests cells in the S phase of the cell cycle and induces apoptosis, and can be used for research on cancer, including prostate cancer and osteosarcoma.
Inhibits cell proliferation and induces caspase-dependent apoptosis in PC-3 cells.
Induces S phase cell cycle arrest in PC-3 and U2OS cells.
Inhibits the growth of U2OS cells.
Increases ROS generation and disrupts mitochondrial membrane potential in U2OS cells.
Inhibits the migration of U2OS cells in vitro.
Modulates expression of Bcl-2, Bax, PARP, and cleaved-caspase-3.
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RVG-Cys acetate is a peptide derived from rabies virus glycoprotein (RVG29). It is designed with a Cys attachment to facilitate subsequent conjugation and enhances the specific targeted delivery of proteins in brain tissue and neurons. This product is for research use only.
Peptide derived from rabies virus glycoprotein (RVG29)
Cys attached for subsequent conjugation
Enhances specific targeted delivery of proteins
Targets brain tissue and neurons
For research use only
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Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi, with 22,23-dihydroergosterol as its precursor. This product is intended for research use only and is not sold for patient use.
Derived from fungi
Precursor is 22,23-dihydroergosterol
For research use only
Appears as an off-white to light yellow solid
Soluble in DMSO at 25 mg/mL
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Antioxidant agent-1 is a new chalcone derivative identified as a potential antioxidant agent. It is intended for research use only and is not sold to patients or validated for medical applications.
New chalcone derivative
Potential antioxidant agent
Suitable for research applications
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Vitamin C (CAS 50-81-7) is a water-soluble vitamin studied extensively in biomedical contexts for its potential anticancer and antiviral activities Mechanistically vitamin C exerts antiproliferative effects on tumor cells and promotes apoptosis as demonstrated in murine colon cancer (CT26) cells At concentrations of 100-200 g/ml vitamin C inhibited proliferation significantly higher levels (200-1000 g/ml) induced apoptosis dose-dependently In vivo studies showed vitamin C treatment reduced tumor volume markedly in CT26 and 4T1 tumor-bearing BALB/c mouse models These findings highlight vitamin C s utility in cancer research as a therapeutic adjunct and investigational agent
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