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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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Luteinizing hormone releasing hormone human acetate salt (LHRH) is a neuropeptide hormone targeting anterior pituitary signaling pathways It is designed to stimulate the anterior pituitary gland thereby promoting secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) LHRH exerts its biological activity primarily by selectively activating matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) key enzymes involved in extracellular matrix remodeling In studies with human endometrial cancer cell lines and decidual stromal cells LHRH mediates induction of MMP-9 expression and activation Based on these pharmacological properties LHRH holds research potential in reproductive biology embryo implantation tumor cell invasiveness and metastasis studies
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iso-VQA-ACC acetate is a substrate for constitutive proteasome. This chemical has a molecular weight of 625.63 (free base) and a purity of 99.48% by HPLC.
Can be stored as a powder at -80°C for 2 years or -20°C for 1 year.
When in solvent, store at -80°C for 6 months or -20°C for 1 month.
Requires sealed storage away from moisture.
Soluble in DMSO at 100 mg/mL (requires ultrasonication).
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Glycyrrhetinic acid (CAS 1449-05-4) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase It is designed to modulate enzymatic activity thereby influencing corticosteroid metabolism and cortisol bioavailability Glycyrrhetinic acid exerts its biological activity primarily through inhibition of 11 -hydroxysteroid dehydrogenase Based on these pharmacological properties glycyrrhetinic acid holds research potential in anti-inflammatory antiviral and hepatoprotective applications
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(+)-Menthol is the dextrorotatory enantiomer of menthol used as a research reagent and antifungal agent. It is supplied as a white to off-white solid and is available as solid and ready-to-use DMSO solutions for in vitro and in vivo studies. Key properties include CAS 15356-60-2, molecular formula C10H20O, molecular weight 156.27 g/mol, and high analytical purity.
High purity (99.95%) suitable for research applications.
White to off-white solid, easy to handle and weigh.
Available as solid and 10 mM DMSO solution formats for convenience.
Soluble in DMSO; in vivo formulation protocols provided for clear solutions ≥2.5 mg/mL.
Defined storage stability for powder and solvent solutions to support long-term studies.
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A plant hormone with diverse roles in disease resistance, plant development, and response to stresses; regulates gene expression and may contribute to epigenetic changes at the chromatin level
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SCH900776 S-isomer is a small-molecule inhibitor targeting checkpoint kinase 1 (Chk1) It is designed to inhibit Chk1 kinase activity thereby interfering with DNA damage-induced checkpoint responses and disrupting S-phase cell-cycle arrest SCH900776 S-isomer exerts its biological activity primarily through selective inhibition of Chk1 kinase (IC50 3 nM) with substantially weaker inhibition toward Chk2 (IC50 1500 nM) and CDK2 (IC50 160 nM) In cellular assays treatment with SCH900776 S-isomer mimics the genetic depletion of CHK1 by RNA interference Based on these pharmacological properties SCH900776 S-isomer holds research potential in oncology particularly in combination with DNA-damaging chemotherapeutics to study enhanced cytotoxicity and altered cell-cycle progression in tumor and leukemia cell lines
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