Organic Acids
Apexbio Technology LLC ENMD-2076 934353-76-1 10mM (in 1mL DMSO)
ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies
Medchemexpress LLC Prednisolone disodium phosphate | 125-02-0 | MFCD00083682 | 99.50% | 25 MG
Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. It is rapidly and completely hydrolyzed into prednisolone in the plasma. This product is intended for research use only.
- Synthetic glucocorticoid
- Possesses anti-inflammatory properties
- Has immunomodulating properties
- Rapidly and completely hydrolyzed into prednisolone in plasma
- White to off-white solid appearance
- Molecular weight of 484.39
- Chemical formula C21H27Na2O8P
- Recommended storage at 4°C, sealed and away from moisture
- In solution, can be stored at -80°C for 6 months or -20°C for 1 month
Bachem D-Lactic acid
D-Lactic acid, 10326-41-7, C3H6O3, Mr 90.08, 250mg. (R)-2-Hydroxy-propionic acid, H-D-Lac-OH.
Ambeed Sodium Citrate, 98%, 25g
Sodium citrate is commonly used in various scientific and industrial applications. This product is a high-purity form of sodium citrate.
- Available with a purity of 98%.
- Packaged in a convenient 25g size for laboratory use.
Medchemexpress LLC 6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine | 934353-76-1 | MFCD16619371 | 100.0% | 375.47 | 10 MG
ENMD-2076 is a multi-targeted kinase inhibitor that selectively binds to and inhibits tyrosine and Aurora kinases. This action can lead to the inhibition of cell division and proliferation, and may induce apoptosis in tumor cells. It also exhibits antiangiogenic activity, making it suitable for various research applications.
- Inhibits multiple kinases including Aurora A, Flt3, KDR/VEGFR2, and FGFR1.
- Demonstrates antiproliferative activity against human cell lines.
- Induces G2-M-phase arrest and apoptosis.
- Inhibits Flt3 ligand (FL)-induced Flt3 autophosphorylation.
- Inhibits VEGFR2/KDR autophosphorylation.
- Shows dose-dependent inhibition of tumor growth in vivo.
Medchemexpress LLC D-(-)-tartaric acid diisopropyl ester | 62961-64-2 | MFCD00008876 | >98.0% | 234.25 g/mol | C10H18O6 | 500 G
D-(-)-Tartaric acid diisopropyl ester is a chiral organic reagent used in synthetic and analytical chemistry for enantioselective reactions, resolution of racemates, and as a chiral building block. It is supplied as a colorless to light yellow liquid with a listed density of 1.119 g/cm3 and is typically handled and stored under cold conditions for long-term stability.
- Chiral building block for enantioselective synthesis.
- Suitable for kinetic resolution and chiral auxiliary applications.
- Colorless to light yellow liquid with density 1.119 g/cm3.
- Typical storage recommendations include cold conditions for long-term stability.
- Available in multiple laboratory pack sizes up to 500 g.
- Purity commonly reported as >98.0% by GC (supplier-specific).
Medchemexpress LLC DL-Tartaric acid | 133-37-9 | 98.0% | 150.09 | C4H6O6 | 500g
DL-Tartaric acid is an orally active and non-racemic mixture of L- and D-tartaric acid with antioxidant activity 14C-labeled DL-Tartaric acid is nephrotoxic[1][2][3]
Apexbio Technology LLC ENMD-2076 934353-76-1 200mg
ENMD-2076 (CAS 934353-76-1) is a selective inhibitor of Aurora A kinase (IC50 14 nM) and FLT3 (IC50 1 86 nM) with additional inhibitory activity against multiple tyrosine kinases implicated in angiogenesis and cell proliferation including RET FLT4/VEGFR3 SRC CSF1R NTRK1 FGFR1/2 VEGFR2/KDR LCK and PDGFR (IC50 1 86 120 nM) ENMD-2076 disrupts cell cycle progression by arresting cells in the G2/M phase through inhibition of Aurora kinases suppresses the PI3K/AKT signaling pathway and demonstrates cytotoxic effects in hematologic malignancy and solid tumor cell lines (in vitro IC50 25 700 nM) In vivo it reduces tumor growth and angiogenesis in xenograft models supporting its use in cancer research and antiangiogenic studies
Medchemexpress LLC Prednisolone (disodium phosphate) | 125-02-0 | MFCD00083682 | 99.0% | 484.39 | C21H27Na2O8P | 10 MG
Prednisolone disodium phosphate (Standard) is an analytical reference standard of the corticosteroid prednisolone, supplied for research and analytical applications. It is provided as a solid and in ready-to-use solution formats for assay development and method validation.
- Analytical reference standard for prednisolone assays.
- Measured purity 98.98% (HPLC) with assay data provided.
- Molecular formula C21H27Na2O8P, molecular weight 484.39 g/mol.
- Available in small to bulk pack sizes, including 10 mg solid and 10 mM solution formats.
- Supplied with datasheet, certificate of analysis, and SDS for traceability.
- Intended for research use only; not for human or veterinary use.